Risk stratification of atrial fibrillation and stroke using single nucleotide polymorphism and circulating biomarkers

• Published in: PloS one Vol. 18; no. 10; p. e0292118
• Main Authors: Sasano, Tetsuo, Ihara, Kensuke, Tanaka, Toshihiro, Furukawa, Tetsushi
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 12.10.2023; Public Library of Science (PLoS)
• Subjects: Analysis; Arrhythmia; Atrial fibrillation; Biological markers; Biology and Life Sciences; Biomarkers; Cardiac arrhythmia; Chromosomes; Congenital diseases; Diagnosis; Disease; Electrocardiography; Ethylenediaminetetraacetic acid; Evaluation; Fibrillation; Genetic analysis; Genetic aspects; Genetic diversity; Genotyping; Health risk assessment; Health risks; Heart failure; Medicine and Health Sciences; MicroRNA; MicroRNAs; miRNA; Nucleotides; Peripheral blood; Plasma; Polymorphism; Risk factors; Scientific equipment and supplies industry; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Statistical significance; Stroke; Stroke (Disease); Thoracic surgery; Japan; United States; Taiwan; United States > US

Background Atrial fibrillation (AF) is the most common sustained arrhythmia, and it causes a high rate of complications such as stroke. It is known that AF begins as paroxysmal form and gradually progresses to persistent form, and sometimes it is difficult to identify paroxysmal AF (PAF) before havi...