Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

• Published in: The Lancet (British edition) Vol. 378; no. 9807; pp. 1917 - 1930
• Main Authors: Nair, Harish, Brooks, W Abdullah, Katz, Mark, Roca, Anna, Berkley, James A, Madhi, Shabir A, Simmerman, James Mark, Gordon, Aubree, Sato, Masatoki, Howie, Stephen, Krishnan, Anand, Ope, Maurice, Lindblade, Kim A, Carosone-Link, Phyllis, Lucero, Marilla, Ochieng, Walter, Kamimoto, Laurie, Dueger, Erica, Bhat, Niranjan, Vong, Sirenda, Theodoratou, Evropi, Chittaganpitch, Malinee, Chimah, Osaretin, Balmaseda, Angel, Buchy, Philippe, Harris, Eva, Evans, Valerie, Katayose, Masahiko, Gaur, Bharti, O'Callaghan-Gordo, Cristina, Goswami, Doli, Arvelo, Wences, Venter, Marietjie, Briese, Thomas, Tokarz, Rafal, Widdowson, Marc-Alain, Mounts, Anthony W, Breiman, Robert F, Feikin, Daniel R, Klugman, Keith P, Olsen, Sonja J, Gessner, Bradford D, Wright, Peter F, Rudan, Igor, Broor, Shobha, Simões, Eric AF, Campbell, Harry
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 03.12.2011; Elsevier; Elsevier Limited
• Subjects: Age; Biological and medical sciences; burden of disease; Child, Preschool; childhood; Children; Children & youth; Data processing; Developing countries; Disease control; General aspects; Global Health; health services; Human viral diseases; Humans; Incidence; Infant; Infection; Infectious diseases; Influenza; Influenza virus; Influenza, Human - complications; Influenza, Human - epidemiology; Internal Medicine; LDCs; Medical research; Medical sciences; meta-analysis; Mortality; Orthomyxoviridae; Pathogens; Pediatrics; Population studies; Respiratory Tract Infections - complications; Respiratory Tract Infections - epidemiology; Reviews; Seasonal variations; Seasons; Streptococcus infections; Studies; Systematic review; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; World Health Organization; Human; Infection; Preschool age; Medicine; Respiratory disease; Seasonal variation; Viral disease; Influenza A; Systematic review; Respiratory system infection; Child; Metaanalysis

The global burden of disease attributable to seasonal influenza virus in children is unknown. We aimed to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than 5 years. We estimated the incidence of influenza episodes, inf...