DNA commission of the International Society of Forensic Genetics: Recommendations on the interpretation of mixtures

• Published in: Forensic science international Vol. 160; no. 2; pp. 90 - 101
• Main Authors: Gill, P., Brenner, C.H., Buckleton, J.S., Carracedo, A., Krawczak, M., Mayr, W.R., Morling, N., Prinz, M., Schneider, P.M., Weir, B.S.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ireland Ltd 13.07.2006; Elsevier; The Lancet Publishing Group, a division of Elsevier Science Ltd; Elsevier Limited
• Subjects: Alleles; Allelomorphism; Analysis; Biological and medical sciences; Biostatistical analysis; DNA - analysis; DNA Fingerprinting - standards; DNA testing; Forensic medicine; Forensic sciences; General aspects; Genotype; Humans; Investigative techniques, diagnostic techniques (general aspects); ISFG DNA commission; Likelihood Functions; Likelihood ratio; Medical sciences; Mixtures; Models, Genetic; Probability of exclusion; Public health. Hygiene; Public health. Hygiene-occupational medicine; Societies, Medical; STR typing; Tandem Repeat Sequences; Likelihood ratio; Probability of exclusion; Biostatistical analysis; Mixtures; STR typing; ISFG DNA commission; Human; Typing; Forensic science; Legal medicine; Commission; Probability; Forensic aspect; Interpretation; Tandemly repeated sequence; Population genetics; Mixture; Recommendation; Analysis; Microsatellite DNA; Society; International
• ISSN: 0379-0738; 1872-6283
• DOI: 10.1016/j.forsciint.2006.04.009

The DNA commission of the International Society of Forensic Genetics (ISFG) was convened at the 21st congress of the International Society for Forensic Genetics held between 13 and 17 September in the Azores, Portugal. The purpose of the group was to agree on guidelines to encourage best practice that can be universally applied to assist with mixture interpretation. In addition the commission was tasked to provide guidance on low copy number (LCN) reporting. Our discussions have highlighted a significant need for continuing education and research into this area. We have attempted to present a consensus from experts but to be practical we do not claim to have conveyed a clear vision in every respect in this difficult subject. For this reason, we propose to allow a period of time for feedback and reflection by the scientific community. Then the DNA commission will meet again to consider further recommendations.