Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy - Swamy, Ravi S.; Reshamwala, Neha; Hunter, Tessa; Vissamsetti, Soujanya; Santos, Carah B.; Baroody, Fuad M.; Hwang, Peter H.; Hoyte, Elisabeth G.; Garcia, Marco A.; Nadeau, Kari C. (Journal of allergy and clinical immunology, 2012)
Keywords: Administration, Sublingual; Adult; adults; allergens; Allergens - immunology; Allergies; Allergy and Immunology; Animals; Asthma; Biological and medical sciences; Bronchi - cytology; Bronchi - immunology; Child; Child, Preschool; children; Cytokines - metabolism; Dermatophagoides; Desensitization, Immunologic - methods; DNA methylation; Double-Blind Method; drug therapy; Dust - immunology; dust mites; epigenetics; Epigenomics; Epithelial Cells - immunology; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene expression; Humans; hypersensitivity; immunoglobulin E; immunoglobulin G; Immunopathology; immunotherapy; Interleukin-1 - metabolism; loci; Lymphocytes; Male; Mast Cells - immunology; Medical sciences; Mites - immunology; nose; patients; Phleum - immunology; Phleum pratense; placebos; regulatory T cell; Respiratory allergies; Rhinitis, Allergic, Seasonal - immunology; Rhinitis, Allergic, Seasonal - therapy; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; sublingual immunotherapy; T-lymphocytes; T-Lymphocytes, Regulatory - immunology; T-Lymphocytes, Regulatory - metabolism; Th2 Cells - immunology; Treatment Outcome; Respiratory allergies; GITR; SLIT; Treg; DM; regulatory T cell; GPS; NDC; epigenetics; TG; Teff; CTLA-4; sublingual immunotherapy; Foxp3; PD-1; Glucocorticoid-induced TNF receptor; Programmed death 1; Forkhead box protein 3; Regulatory T; Timothy grass; Cytotoxic T-lymphocyte antigen 4; Grass pollen season; CD4 + effector T; Dust mite; Nasal disk challenge; Human; Allergy; Immunopathology; Modification; Desensitization; Sublingual administration; Respiratory system; Immunology; T-Lymphocyte; Epigenetics; Regulatory cell