Lung cancer: current therapies and new targeted treatments

• Published in: The Lancet (British edition) Vol. 389; no. 10066; pp. 299 - 311
• Main Authors: Hirsch, Fred R, Scagliotti, Giorgio V, Mulshine, James L, Kwon, Regina, Curran, Walter J, Wu, Yi-Long, Paz-Ares, Luis
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 21.01.2017; Elsevier Limited
• Subjects: Antineoplastic Agents - therapeutic use; Cancer therapies; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - genetics; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - therapy; Combined Modality Therapy; Early Detection of Cancer; Humans; Immunotherapy; Internal Medicine; Lung cancer; Lung Neoplasms - diagnosis; Lung Neoplasms - genetics; Lung Neoplasms - mortality; Lung Neoplasms - therapy; Medical screening; Mutation; Oncology; Prevention; Survival; Survival Rate

Lung cancer is the most frequent cause of cancer-related deaths worldwide. Every year, 1·8 million people are diagnosed with lung cancer, and 1·6 million people die as a result of the disease. 5-year survival rates vary from 4–17% depending on stage and regional differences. In this Seminar, we disc...