Novel Insights into the Pathogenesis of Hirschsprung's-associated Enterocolitis

• Published in: Chinese medical journal Vol. 129; no. 12; pp. 1491 - 1497
• Main Authors: Jiao, Chun-Lei, Chen, Xu-Yong, Feng, Jie-Xiong
• Format: Journal Article
• Language: English
• Published: China Wolters Kluwer - Medknow Publications 20.06.2016; Medknow Publications and Media Pvt. Ltd; Lippincott Williams & Wilkins Ovid Technologies; Department of Pediatric Surgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei 430000, China; Medknow Publications & Media Pvt Ltd; Wolters Kluwer
• Subjects: Analysis; Animals; Colon; Enterocolitis - etiology; Enterocolitis - pathology; Enterocolitis; Hirschsprung's-associated Enterocolitis; Hirschsprung's Disease; Pathogenesis; Health aspects; Hirschsprung Disease - complications; Hirschsprung Disease - pathology; Hirschsprung's disease; Humans; Immune system; Intestines - microbiology; Intestines - pathology; Microbiota (Symbiotic organisms); Review; Risk factors; Rodents; Small intestine; Studies; Hirschsprung's-associated Enterocolitis; Hirschsprung's Disease; Enterocolitis; Pathogenesis

Objective: To systematically summary the updated results about the pathogenesis of Hirschsprung's-associated enterocolitis (HAEC). Besides, we discussed the research key and direction based on these results. Data Sources: Our data cited in this review were obtained mainly from PubMed from 1975...