Cardiac-Specific Overexpression of Caveolin-3 Attenuates Cardiac Hypertrophy and Increases Natriuretic Peptide Expression and Signaling - Horikawa, Yousuke T.; Panneerselvam, Mathivadhani; Kawaraguchi, Yoshitaka; Tsutsumi, Yasuo M.; Ali, Sameh S.; Balijepalli, Ravi C.; Murray, Fiona; Head, Brian P.; Niesman, Ingrid R.; Rieg, Timo; Vallon, Volker; Insel, Paul A.; et al. (Journal of the American College of Cardiology, 2011)
Keywords: Animals; Atrial Natriuretic Factor - blood; Atrial Natriuretic Factor - metabolism; atrial natriuretic peptide (ANP); Biological and medical sciences; brain natriuretic peptide (BNP); Cardiology; Cardiology. Vascular system; Cardiomegaly - drug therapy; Cardiomegaly - metabolism; Cardiomegaly - physiopathology; Cardiomegaly - prevention & control; Cardiomyopathy; Cardiovascular; caveolae; Caveolae - metabolism; caveolin; Caveolin 3 - metabolism; Cyclic GMP - metabolism; Food; Heart failure; Heart Failure - drug therapy; Heart Failure - metabolism; hypertrophy; Immunoenzyme Techniques; In Vitro Techniques; Internal Medicine; Intubation; Kinases; Laboratory animals; Medical sciences; Mice; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac - metabolism; Natriuretic Peptide, Brain - blood; Natriuretic Peptide, Brain - metabolism; NFATC Transcription Factors - metabolism; Peptides; Potassium; Proteins; remodeling; RNA, Messenger - metabolism; Rodents; Signal transduction; Software; Urine; Cav-3 OE; remodeling; ANP; RNA; hypertrophy; BNP; NFATc3; cGMP; CM; LV; WGA; PI3K; MβCD; atrial natriuretic peptide (ANP); TAC; brain natriuretic peptide (BNP); Cav; cDNA; caveolae; caveolin; cyclic guanosine monophosphate; ribonucleic acid; brain natriuretic peptide; complementary deoxyribonucleic acid; nuclear factor of activated T-cell; left ventricle/ventricular; wheat germ agglutinin; atrial natriuretic peptide; phosphatidylinositol-3-kinase; overexpression of caveolin-3; cardiac myocyte; methyl-β-cyclodextrin; transverse aortic constriction; Heart; Peptides; Increase; Circulatory system; Cardiology; Gene expression; Hypertrophy