Effects of SSRI treatment on GABA and glutamate levels in an associative relearning paradigm - Spurny, B.; Vanicek, T.; Seiger, R.; Reed, M.B.; Klöbl, M.; Ritter, V.; Unterholzner, J.; Godbersen, G.M.; Silberbauer, L.R.; Pacher, D.; Klug, S.; Konadu, M.E.; et al. (NeuroImage (Orlando, Fla.), 2021)
Keywords: Adult; Animal cognition; Antidepressants; Association Learning - drug effects; Association Learning - physiology; Brain; Brain - diagnostic imaging; Brain - drug effects; Brain - metabolism; Citalopram; Cognitive ability; Creatine; Double-Blind Method; Drug abuse; Female; GABA; gamma-Aminobutyric Acid - metabolism; Gene expression; Globus pallidus; Glutamate; Glutamatergic transmission; Glutamic Acid - metabolism; Glutamine; Hippocampus; Humans; Interneurons; Learning; Longitudinal Studies; Macromolecules; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Magnetic resonance spectroscopy; Magnetic Resonance Spectroscopy - methods; Male; Memory; Mental disorders; MRSI; Neuroimaging; Neurotransmission; Neurotransmitters; Photic Stimulation - methods; Placebos; Putamen; Recovery of function; Relearning; Selective Serotonin Reuptake Inhibitors - pharmacology; Serotonin; Serotonin transporter; Serotonin uptake inhibitors; Spectrum analysis; SSRI; Thalamus; Young Adult; γ-Aminobutyric acid; Learning; GABA; SSRI; Glutamate; Hippocampus; MRSI