Does Internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials

• Published in: Psychological medicine Vol. 46; no. 13; pp. 2679 - 2693
• Main Authors: Ebert, D. D., Donkin, L., Andersson, G., Andrews, G., Berger, T., Carlbring, P., Rozenthal, A., Choi, I., Laferton, J. A. C., Johansson, R., Kleiboer, A., Lange, A., Lehr, D., Reins, J. A., Funk, B., Newby, J., Perini, S., Riper, H., Ruwaard, J., Sheeber, L., Snoek, F. J., Titov, N., Ünlü Ince, B., van Bastelaar, K., Vernmark, K., van Straten, A., Warmerdam, L., Salsman, N., Cuijpers, P.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.10.2016
• Subjects: Adverse events; Clinical trials; Confidence intervals; Data processing; Depression; Depressive Disorder, Major - therapy; Deterioration; deterioration effect; Education; Higher education; Humans; Internet; Internet-based guided self-help; Intervention; Mental depression; Meta-analysis; Moderators; negative effects; Outcome Assessment (Health Care); Patients; Psychology; psykologi; Randomized Controlled Trials as Topic; Self Care - adverse effects; Self Care - methods; Self help; Studies; Systematic review; Oregon; Sweden; Netherlands; Australia; United States > US; Germany; deterioration effect; depression; negative effects; Adverse events; Internet-based guided self-help

Almost nothing is known about the potential negative effects of Internet-based psychological treatments for depression. This study aims at investigating deterioration and its moderators within randomized trials on Internet-based guided self-help for adult depression, using an individual patient data...