Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells - Jiang, Xiaofeng; Zhu, Shimei; Panetti, Tracee S; Bromberg, Michael E (Thrombosis and haemostasis, 2008)
Keywords: Breast Neoplasms - enzymology; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cell Line, Tumor; Cell Movement - drug effects; Chromones - pharmacology; Factor VIIa - metabolism; Factor Xa - metabolism; Female; Humans; Morpholines - pharmacology; Neoplasm Invasiveness; Peptides - pharmacology; Phosphorylation; Protein Kinase Inhibitors - pharmacology; Protein Kinases - drug effects; Protein Kinases - metabolism; Proto-Oncogene Proteins c-akt - antagonists & inhibitors; Proto-Oncogene Proteins c-akt - metabolism; Receptor, PAR-1 - metabolism; Receptor, PAR-2 - metabolism; Recombinant Proteins - metabolism; Ribosomal Protein S6 Kinases, 70-kDa - metabolism; Sirolimus - pharmacology; Thromboplastin - metabolism; TOR Serine-Threonine Kinases