Learning-related fine-scale specificity imaged in motor cortex circuits of behaving mice

• Published in: Nature (London) Vol. 464; no. 7292; pp. 1182 - 1186
• Main Authors: Komiyama, Takaki, Sato, Takashi R., O’Connor, Daniel H., Zhang, Ying-Xin, Huber, Daniel, Hooks, Bryan M., Gabitto, Mariano, Svoboda, Karel
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.04.2010; Nature Publishing Group
• Subjects: 631/378/1595; 631/378/2632/1663; 631/601/18; Animals; Axonal Transport; Behavior, Animal - physiology; Biological and medical sciences; Brain; Choice Behavior - physiology; Fundamental and applied biological sciences. Psychology; Humanities and Social Sciences; Learning - physiology; Learning in animals; letter; Male; Methods; Mice; Mice, Inbred C57BL; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration; Motor cortex; Motor Cortex - cytology; Motor Cortex - physiology; Motor Neurons - physiology; multidisciplinary; Neural Pathways - physiology; Neurons; Neurophysiology; Odorants - analysis; Physiological aspects; Properties; Pyramidal Cells - physiology; Reward; Science; Stimulation, Chemical; Time Factors; Tongue - cytology; Tongue - innervation; Tongue - physiology; Vertebrates: nervous system and sense organs; United States; Tongue; Motor pathway; Calcium; Rodentia; Central nervous system; Frontal cortex; Motor control; Photon; Encephalon; Learning; Vertebrata; Mammalia; Acquisition process; Neuron; Mouse; Animal; Motor cortex; Imaging; Plasticity; Behavior

Cortical circuits: learning to behave Although it is generally accepted that specific cortical circuits drive behavioural execution, the relationship between task performance and modulation within the circuit is unknown. Taking advantage of a technique that allows simultaneous activity monitoring of...