The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder

•ADHD occurs in 5.9 % of youth and 2.5 % of adults.•Most cases of ADHD are caused by the combined effects of many genetic and environmental risks.•There are small differences in the brain between people with and without ADHD.•Untreated ADHD can lead to many adverse outcomes.•ADHD costs society hundr...

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Published inNeuroscience and biobehavioral reviews Vol. 128; pp. 789 - 818
Main Authors Faraone, Stephen V., Banaschewski, Tobias, Coghill, David, Zheng, Yi, Biederman, Joseph, Bellgrove, Mark A., Newcorn, Jeffrey H., Gignac, Martin, Al Saud, Nouf M., Manor, Iris, Rohde, Luis Augusto, Yang, Li, Cortese, Samuele, Almagor, Doron, Stein, Mark A., Albatti, Turki H., Aljoudi, Haya F., Alqahtani, Mohammed M.J., Asherson, Philip, Atwoli, Lukoye, Bölte, Sven, Buitelaar, Jan K., Crunelle, Cleo L., Daley, David, Dalsgaard, Søren, Döpfner, Manfred, Espinet (on behalf of CADDRA), Stacey, Fitzgerald, Michael, Franke, Barbara, Gerlach, Manfred, Haavik, Jan, Hartman, Catharina A., Hartung, Cynthia M., Hinshaw, Stephen P., Hoekstra, Pieter J., Hollis, Chris, Kollins, Scott H., Sandra Kooij, J.J., Kuntsi, Jonna, Larsson, Henrik, Li, Tingyu, Liu, Jing, Merzon, Eugene, Mattingly, Gregory, Mattos, Paulo, McCarthy, Suzanne, Mikami, Amori Yee, Molina, Brooke S.G., Nigg, Joel T., Purper-Ouakil, Diane, Omigbodun, Olayinka O., Polanczyk, Guilherme V., Pollak, Yehuda, Poulton, Alison S., Rajkumar, Ravi Philip, Reding, Andrew, Reif, Andreas, Rubia, Katya, Rucklidge, Julia, Romanos, Marcel, Ramos-Quiroga, J. Antoni, Schellekens, Arnt, Scheres, Anouk, Schoeman, Renata, Schweitzer, Julie B., Shah, Henal, Solanto, Mary V., Sonuga-Barke, Edmund, Soutullo, César, Steinhausen, Hans-Christoph, Swanson, James M., Thapar, Anita, Tripp, Gail, van de Glind, Geurt, van den Brink, Wim, Van der Oord, Saskia, Venter, Andre, Vitiello, Benedetto, Walitza, Susanne, Wang, Yufeng
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.09.2021
Elsevier
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Abstract •ADHD occurs in 5.9 % of youth and 2.5 % of adults.•Most cases of ADHD are caused by the combined effects of many genetic and environmental risks.•There are small differences in the brain between people with and without ADHD.•Untreated ADHD can lead to many adverse outcomes.•ADHD costs society hundreds of billions of dollars each year, worldwide. Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
AbstractList •ADHD occurs in 5.9 % of youth and 2.5 % of adults.•Most cases of ADHD are caused by the combined effects of many genetic and environmental risks.•There are small differences in the brain between people with and without ADHD.•Untreated ADHD can lead to many adverse outcomes.•ADHD costs society hundreds of billions of dollars each year, worldwide. Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base.Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder.Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents.Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. METHODS: We reviewed studies with more than 2,000 participants or meta-analyses from five or more studies or 2,000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. RESULTS: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 79 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 362 people who have read this document and agree with its contents. CONCLUSIONS: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base.BACKGROUNDMisconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base.We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder.METHODSWe reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder.We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents.RESULTSWe generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents.Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.CONCLUSIONSMany findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.
Author Cortese, Samuele
Walitza, Susanne
Yang, Li
Haavik, Jan
Hollis, Chris
Solanto, Mary V.
Hartung, Cynthia M.
Banaschewski, Tobias
Coghill, David
Romanos, Marcel
Wang, Yufeng
Mikami, Amori Yee
Tripp, Gail
Li, Tingyu
Schoeman, Renata
van den Brink, Wim
Döpfner, Manfred
Thapar, Anita
Merzon, Eugene
Asherson, Philip
Liu, Jing
Mattingly, Gregory
Al Saud, Nouf M.
Poulton, Alison S.
Pollak, Yehuda
Zheng, Yi
Sonuga-Barke, Edmund
Polanczyk, Guilherme V.
Manor, Iris
Van der Oord, Saskia
van de Glind, Geurt
Gerlach, Manfred
Vitiello, Benedetto
Rajkumar, Ravi Philip
Espinet (on behalf of CADDRA), Stacey
Scheres, Anouk
Shah, Henal
Bellgrove, Mark A.
Crunelle, Cleo L.
Aljoudi, Haya F.
Rucklidge, Julia
McCarthy, Suzanne
Daley, David
Schweitzer, Julie B.
Bölte, Sven
Mattos, Paulo
Swanson, James M.
Reif, Andreas
Rubia, Katya
Venter, Andre
Franke, Barbara
Hoekstra, Pieter J.
Larsson, Henrik
Rohde, Luis Augusto
Fitzgerald, Michael
Faraone, Stephen V.
Sandra Kooij, J.J.
Steinhausen, Hans-Christoph
Biederman, Joseph
Nigg, Joel T.
Almagor, Doron
Kollins, Scott H.
Albatti
AuthorAffiliation 118 Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
35 Canadian ADHD Research Alliance (CADDRA), Canada
156 Department of Pediatrics, University of California Irvine, Irvine, CA, USA
159 Hogeschool van Utrecht/ University of Applied Sciences, Utrecht, The Netherlands
110 INSERM U 1018 CESP-Developmental Psychiatry, France
32 Hassenfeld Children’s Hospital at NYU Langone, New York University Child Study Center, NewYork City, NY, USA
83 Duke Clinical Research Institute, Durham, NC, USA
129 Biomedical Network Research Centre on Mental Health (CIBERSAM), Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain
120 Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
104 Brazilian Attention Deficit Association (ABDA), Brazil
53 International Collaboration on ADHD and Substance Abuse (ICASA), Nijmegen, The Netherlands
65 Department of Biomedicine, University of Bergen, Bergen, Norway
14
AuthorAffiliation_xml – name: 88 Neurodevelopmental Disorders Across Lifespan Section of European Psychiatric Association, France
– name: 83 Duke Clinical Research Institute, Durham, NC, USA
– name: 156 Department of Pediatrics, University of California Irvine, Irvine, CA, USA
– name: 19 Department of Child and Adolescent Psychiatry, Montreal Children’s Hospital, MUHC, Montreal, Canada
– name: 67 University of Groningen, Groningen, The Netherlands
– name: 75 Association for Psychological Science, USA
– name: 111 Centre for Child & Adolescent Mental Health, College of Medicine, University of Ibadan, Ibadan, Nigeria
– name: 112 Department of Child & Adolescent Psychiatry, University College Hospital, Ibadan, Nigeria
– name: 125 Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
– name: 145 The Zucker School of Medicine at Hofstra-Northwell, Northwell Health, Hemstead, NY, USA
– name: 51 Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands
– name: 40 Consultant Clinical Neuropsychologist, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
– name: 21 Chair, Canadian ADHD Research Alliance (CADDRA), Canada
– name: 165 Johns Hopkins University School of Public Health, Baltimore, MD, USA
– name: 120 Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
– name: 127 Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Catalonia, Spain
– name: 22 Chairman, Board of Directors, Saudi ADHD Society, Saudi Arabia
– name: 81 NIHR Nottingham Biomedical Research Centre, Nottingham, UK
– name: 37 University of Washington, Seattle, WA, USA
– name: 14 Clinical & Research Programs in Pediatric Psychopharmacology & Adult ADHD, Massachusetts General Hospital, Boston, MA, USA
– name: 53 International Collaboration on ADHD and Substance Abuse (ICASA), Nijmegen, The Netherlands
– name: 146 Professional Advisory Board, Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), USA
– name: 2 World Federation of ADHD, Switzerland
– name: 15 Department of Psychiatry, Harvard Medical School, Boston, MA, USA
– name: 131 Chair of Neurodevelopmental Disorders Across Lifespan Section of European Psychiatric Association, France
– name: 107 Departments of Psychiatry, Psychology, Pediatrics, Clinical & Translational Science, University of Pittsburgh, Pittsburgh, PA, USA
– name: 151 Louis A. Faillace MD, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA
– name: 135 International Collaboration on ADHD and Substance Abuse (ICASA), Nijmegen, The Netherlands
– name: 31 Solent NHS Trust, Southampton, UK
– name: 136 Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands
– name: 12 Asian Federation of ADHD, China
– name: 60 Canadian ADHD Resource Alliance (CADDRA), Canada
– name: 4 Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
– name: 18 Departments of Psychiatry and Pediatrics, Division of ADHD and Learning Disorders, Icahn School of Medicine at Mount Sinai, New York, NY, USA
– name: 17 President, Australian ADHD Professionals Association (AADPA), Australia
– name: 153 University of Basel, CH, Switzerland
– name: 141 American Psychiatric Association, USA
– name: 143 Department of Psychiatry and Behavioral Sciences and the MIND Institute, University of California, Davis, Sacramento, CA, USA
– name: 159 Hogeschool van Utrecht/ University of Applied Sciences, Utrecht, The Netherlands
– name: 103 D’Or Institute for Research and Education, Rio de Janeiro, Brazil
– name: 166 Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland
– name: 54 Division of Psychiatry and Applied Psychology, School of Medicine University of Nottingham, Nottingham, UK
– name: 9 The National Clinical Research Center for Mental Disorders, Beijing, China
– name: 93 National Research Center for Clinical Medicine of Child Health and Disease, Chongqing, China
– name: 82 Duke University School of Medicine, Durham, NC, USA
– name: 90 School of Medical Sciences, Örebro University, Örebro, Sweden
– name: 55 NIHR MindTech Mental Health MedTech Cooperative & Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan (CANDAL), Institute of Mental Health, University of Nottingham, Nottingham, UK
– name: 148 Professional Advisory Board, National Center for Children with Learning Disabilities (NCLD), USA
– name: 73 University of California, San Fancisco, CA, USA
– name: 95 The Chinese Society of Child and Adolescent Psychiatry, China
– name: 11 Beijing Institute for Brain Disorders, Beijing, China
– name: 122 Department of Child & Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neurosciences, King’s College London, London, UK
– name: 132 Board Member, International Collaboration on ADHD and Substance Abuse (ICASA), The Netherlands
– name: 164 University of Torino, Torino, Italy
– name: 140 World Federation of Biological Psychiatry, Germany
– name: 110 INSERM U 1018 CESP-Developmental Psychiatry, France
– name: 108 Center for ADHD Research, Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA
– name: 163 University of the Free State, Bloemfontein, South Africa
– name: 5 Child and Adolescent Psychiatrist’s Representative, Zentrales-ADHS-Netz, Germany
– name: 23 Associate professor and head of the ADHD clinic, Geha MHC, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
– name: 34 University of Toronto, Department of Psychiatry and SickKids Centre for Community Mental Health, Toronto, Canada
– name: 157 Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Wales, UK
– name: 147 Professional Advisory Board, American Professional Society of ADHD and Related Disorders (APSARD), USA
– name: 26 Department of Psychiatry, Federal University of Rio Grande do Sul, Brazil
– name: 1 Departments of Psychiatry and Neuroscience and Physiology, Psychiatry Research Division, SUNY Upstate Medical University, Syracuse, NY, USA
– name: 70 ADHD across the Lifespan Network from European College of Neuropsychopharmacology​(ECNP), The Netherlands
– name: 144 Topiwala National Medical College & BYL Nair Ch. Hospital, Mumbai, India
– name: 106 University of British Columbia, Vancouver, BC, Canada
– name: 149 Department of Child and Adolescent Psychaitry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
– name: 76 Society for Research in Child Development, USA
– name: 84 Associate Professor of Psychiatry, Amsterdam University Medical Center (VUMc), Amsterdam, The Netherlands
– name: 59 Psychologist’s Representative, Zentrales-ADHS-Netz, Germany
– name: 105 School of Pharmacy, University College Cork, Cork, Ireland
– name: 16 Turner Institute for Brain and Mental Health and School of Psychological Sciences, Monash University, Clayton VIC, Australia
– name: 161 Psychology and Educational Sciences, KU Leuven, Leuven, Belgium
– name: 96 The Asian Society for Child and Adolescent Psychiatry and Allied Professions, China
– name: 6 The German Association of Child and Adolescent Psychiatry and Psychotherapy, Germany
– name: 25 Co-chair, Neurodevelopmental section in the European Psychiatric Association (EPA), France
– name: 126 Zentrales-ADHS-Netz, Germany
– name: 58 Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, School of Child and Adolescent Cognitive Behavior Therapy (AKiP), Faculty of Medicine and University Hospital Cologne, University Cologne, Cologne, Germany
– name: 61 Former Professor or Child Psychiatry, Trinity College, Dublin, Ireland
– name: 86 European Network Adult ADHD, The Netherlands
– name: 29 Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
– name: 152 University of Zurich, CH, Switzerland
– name: 78 University of Nottingham, Nottingham, UK
– name: 102 Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
– name: 130 Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain
– name: 56 National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
– name: 100 Chair of ADHD Section, Israeli National Diabetes Council, Israel
– name: 160 Amsterdam University Medical Centers, Academic Medical Center, Amsterdam, The Netherlands
– name: 117 Australian ADHD Professionals Association (AADPA), Australia
– name: 42 Clinical Psychology, King Khalid University, Abha, Saudi Arabia
– name: 50 Curtin Autism Research Group, School of Occupational Therapy, Social Work and Speech Pathology, Curtin University, Perth, Western Australia
– name: 116 Brain Mind Centre Nepean, University of Sydney, Sydney, Australia
– name: 36 The Possibilities Clinic, Toronto, On, Canada
– name: 80 NIHR MindTech MedTech Co-operative, Nottingham, UK
– name: 91 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden
– name: 3 American Professional Society of ADHD and Related Disorders (APSARD), USA
– name: 20 Child and Adolescent Psychiatry Division, McGill University, Montreal, Canada
– name: 66 Division of Psychiatry, Haukeland University Hospital, Bergen, Norway
Author_xml – sequence: 1
  givenname: Stephen V.
  orcidid: 0000-0002-9217-3982
  surname: Faraone
  fullname: Faraone, Stephen V.
  email: sfaraone@childpsychresearch.org
  organization: Departments of Psychiatry and Neuroscience and Physiology, Psychiatry Research Division, SUNY Upstate Medical University, Syracuse, NY, USA
– sequence: 2
  givenname: Tobias
  orcidid: 0000-0003-4595-1144
  surname: Banaschewski
  fullname: Banaschewski, Tobias
  organization: Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
– sequence: 3
  givenname: David
  surname: Coghill
  fullname: Coghill, David
  organization: Departments of Paediatrics and Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia
– sequence: 4
  givenname: Yi
  surname: Zheng
  fullname: Zheng, Yi
  organization: Beijing Anding Hospital, Capital Medical University, Beijing, China
– sequence: 5
  givenname: Joseph
  surname: Biederman
  fullname: Biederman, Joseph
  organization: Clinical & Research Programs in Pediatric Psychopharmacology & Adult ADHD, Massachusetts General Hospital, Boston, MA, USA
– sequence: 6
  givenname: Mark A.
  surname: Bellgrove
  fullname: Bellgrove, Mark A.
  organization: Turner Institute for Brain and Mental Health and School of Psychological Sciences, Monash University, Clayton, VIC, Australia
– sequence: 7
  givenname: Jeffrey H.
  surname: Newcorn
  fullname: Newcorn, Jeffrey H.
  organization: American Professional Society of ADHD and Related Disorders (APSARD), USA
– sequence: 8
  givenname: Martin
  surname: Gignac
  fullname: Gignac, Martin
  organization: Department of Child and Adolescent Psychiatry, Montreal Children’s Hospital, MUHC, Montreal, Canada
– sequence: 9
  givenname: Nouf M.
  surname: Al Saud
  fullname: Al Saud, Nouf M.
  organization: Saudi ADHD Society, Saudi Arabia
– sequence: 10
  givenname: Iris
  surname: Manor
  fullname: Manor, Iris
  organization: Chair, Israeli Society of ADHD (ISA), Israel
– sequence: 11
  givenname: Luis Augusto
  surname: Rohde
  fullname: Rohde, Luis Augusto
  organization: Department of Psychiatry, Federal University of Rio Grande do Sul, Brazil
– sequence: 12
  givenname: Li
  surname: Yang
  fullname: Yang, Li
  organization: Asian Federation of ADHD, China
– sequence: 13
  givenname: Samuele
  surname: Cortese
  fullname: Cortese, Samuele
  organization: Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton,UK
– sequence: 14
  givenname: Doron
  orcidid: 0000-0003-2347-237X
  surname: Almagor
  fullname: Almagor, Doron
  organization: University of Toronto, SickKids Centre for Community Mental Health, Toronto, Canada
– sequence: 15
  givenname: Mark A.
  surname: Stein
  fullname: Stein, Mark A.
  organization: University of Washington, Seattle, WA, USA
– sequence: 16
  givenname: Turki H.
  surname: Albatti
  fullname: Albatti, Turki H.
  organization: Saudi ADHD Society Medical and Psychological Committee, Saudi Arabia
– sequence: 17
  givenname: Haya F.
  surname: Aljoudi
  fullname: Aljoudi, Haya F.
  organization: King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
– sequence: 18
  givenname: Mohammed M.J.
  surname: Alqahtani
  fullname: Alqahtani, Mohammed M.J.
  organization: Clinical Psychology, King Khalid University, Abha, Saudi Arabia
– sequence: 19
  givenname: Philip
  surname: Asherson
  fullname: Asherson, Philip
  organization: Social Genetic & Developmental Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, UK
– sequence: 20
  givenname: Lukoye
  orcidid: 0000-0001-7710-9723
  surname: Atwoli
  fullname: Atwoli, Lukoye
  organization: Department of Mental Health and Behavioural Science, Moi University School of Medicine, Eldoret, Kenya
– sequence: 21
  givenname: Sven
  surname: Bölte
  fullname: Bölte, Sven
  organization: Center of Neurodevelopmental Disorders (KIND), Centre for Psychiatry Research; Department of Women’s and Children’s Health, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Sweden
– sequence: 22
  givenname: Jan K.
  surname: Buitelaar
  fullname: Buitelaar, Jan K.
  organization: Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, the Netherlands
– sequence: 23
  givenname: Cleo L.
  orcidid: 0000-0002-8798-0448
  surname: Crunelle
  fullname: Crunelle, Cleo L.
  organization: Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Dept. of Psychiatry, Brussel, Belgium
– sequence: 24
  givenname: David
  surname: Daley
  fullname: Daley, David
  organization: Division of Psychiatry and Applied Psychology, School of Medicine University of Nottingham, Nottingham, UK
– sequence: 25
  givenname: Søren
  orcidid: 0000-0003-4659-0969
  surname: Dalsgaard
  fullname: Dalsgaard, Søren
  organization: National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
– sequence: 26
  givenname: Manfred
  surname: Döpfner
  fullname: Döpfner, Manfred
  organization: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, School of Child and Adolescent Cognitive Behavior Therapy (AKiP), Faculty of Medicine and University Hospital Cologne, University Cologne, Cologne, Germany
– sequence: 27
  givenname: Stacey
  orcidid: 0000-0002-3427-1736
  surname: Espinet (on behalf of CADDRA)
  fullname: Espinet (on behalf of CADDRA), Stacey
  organization: Canadian ADHD Resource Alliance (CADDRA), Canada
– sequence: 28
  givenname: Michael
  surname: Fitzgerald
  fullname: Fitzgerald, Michael
  organization: Trinity College, Dublin, Ireland
– sequence: 29
  givenname: Barbara
  surname: Franke
  fullname: Franke, Barbara
  organization: Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands
– sequence: 30
  givenname: Manfred
  surname: Gerlach
  fullname: Gerlach, Manfred
  email: manfred.gerlach@uni-wuerzburg.de
  organization: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Wuerzburg, Germany
– sequence: 31
  givenname: Jan
  orcidid: 0000-0001-7865-2808
  surname: Haavik
  fullname: Haavik, Jan
  organization: Department of Biomedicine, University of Bergen, Bergen, Norway
– sequence: 32
  givenname: Catharina A.
  surname: Hartman
  fullname: Hartman, Catharina A.
  organization: University of Groningen, Groningen, the Netherlands
– sequence: 33
  givenname: Cynthia M.
  orcidid: 0000-0003-2210-8373
  surname: Hartung
  fullname: Hartung, Cynthia M.
  organization: Department of Psychology, University of Wyoming, Laramie, WY, USA
– sequence: 34
  givenname: Stephen P.
  orcidid: 0000-0001-6497-1082
  surname: Hinshaw
  fullname: Hinshaw, Stephen P.
  organization: University of California, Berkeley, CA, USA
– sequence: 35
  givenname: Pieter J.
  surname: Hoekstra
  fullname: Hoekstra, Pieter J.
  organization: University of Groningen, University Medical Center Groningen, Department of Child and Adolescent Psychiatry, Groningen, the Netherlands
– sequence: 36
  givenname: Chris
  surname: Hollis
  fullname: Hollis, Chris
  organization: Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, New York, USA; Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK
– sequence: 37
  givenname: Scott H.
  surname: Kollins
  fullname: Kollins, Scott H.
  organization: Duke University School of Medicine, Durham, NC, USA
– sequence: 38
  givenname: J.J.
  surname: Sandra Kooij
  fullname: Sandra Kooij, J.J.
  organization: Amsterdam University Medical Center (VUMc), Amsterdam, the Netherlands
– sequence: 39
  givenname: Jonna
  orcidid: 0000-0002-0113-8162
  surname: Kuntsi
  fullname: Kuntsi, Jonna
  organization: Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
– sequence: 40
  givenname: Henrik
  surname: Larsson
  fullname: Larsson, Henrik
  organization: School of Medical Sciences, Örebro University, Örebro, Sweden
– sequence: 41
  givenname: Tingyu
  surname: Li
  fullname: Li, Tingyu
  organization: Growth, Development and Mental Health Center for Children and Adolescents, Children's Hospital of Chongqing Medical University, Chongqing, China
– sequence: 42
  givenname: Jing
  surname: Liu
  fullname: Liu, Jing
  organization: Asian Federation of ADHD, China
– sequence: 43
  givenname: Eugene
  orcidid: 0000-0001-5469-0236
  surname: Merzon
  fullname: Merzon, Eugene
  organization: Department of Family Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
– sequence: 44
  givenname: Gregory
  surname: Mattingly
  fullname: Mattingly, Gregory
  organization: Washington University, St. Louis, MO, USA
– sequence: 45
  givenname: Paulo
  surname: Mattos
  fullname: Mattos, Paulo
  organization: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
– sequence: 46
  givenname: Suzanne
  surname: McCarthy
  fullname: McCarthy, Suzanne
  organization: School of Pharmacy, University College Cork, Cork, Ireland
– sequence: 47
  givenname: Amori Yee
  orcidid: 0000-0001-5821-0674
  surname: Mikami
  fullname: Mikami, Amori Yee
  organization: University of British Columbia, Vancouver, BC, Canada
– sequence: 48
  givenname: Brooke S.G.
  surname: Molina
  fullname: Molina, Brooke S.G.
  organization: Departments of Psychiatry, Psychology, Pediatrics, Clinical & Translational Science, University of Pittsburgh, Pittsburgh, PA, USA
– sequence: 49
  givenname: Joel T.
  surname: Nigg
  fullname: Nigg, Joel T.
  organization: Center for ADHD Research, Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA
– sequence: 50
  givenname: Diane
  orcidid: 0000-0003-0454-1579
  surname: Purper-Ouakil
  fullname: Purper-Ouakil, Diane
  organization: University of Montpellier, CHU Montpellier Saint Eloi, MPEA, Medical and Psychological Unit for Children and Adolescents (MPEA), Montpellier, France
– sequence: 51
  givenname: Olayinka O.
  orcidid: 0000-0003-3808-8530
  surname: Omigbodun
  fullname: Omigbodun, Olayinka O.
  organization: Centre for Child & Adolescent Mental Health, College of Medicine, University of Ibadan, Ibadan, Nigeria
– sequence: 52
  givenname: Guilherme V.
  surname: Polanczyk
  fullname: Polanczyk, Guilherme V.
  organization: Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
– sequence: 53
  givenname: Yehuda
  surname: Pollak
  fullname: Pollak, Yehuda
  organization: Seymour Fox School of Education, The Hebrew University of Jerusalem, Israel
– sequence: 54
  givenname: Alison S.
  orcidid: 0000-0002-5867-2403
  surname: Poulton
  fullname: Poulton, Alison S.
  organization: Brain Mind Centre Nepean, University of Sydney, Sydney, Australia
– sequence: 55
  givenname: Ravi Philip
  orcidid: 0000-0003-2699-7438
  surname: Rajkumar
  fullname: Rajkumar, Ravi Philip
  organization: Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
– sequence: 56
  givenname: Andrew
  orcidid: 0000-0001-6000-1425
  surname: Reding
  fullname: Reding, Andrew
  organization: USA
– sequence: 57
  givenname: Andreas
  orcidid: 0000-0002-0992-634X
  surname: Reif
  fullname: Reif, Andreas
  organization: Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
– sequence: 58
  givenname: Katya
  surname: Rubia
  fullname: Rubia, Katya
  organization: World Federation of ADHD, Switzerland
– sequence: 59
  givenname: Julia
  surname: Rucklidge
  fullname: Rucklidge, Julia
  organization: School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand
– sequence: 60
  givenname: Marcel
  surname: Romanos
  fullname: Romanos, Marcel
  organization: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
– sequence: 61
  givenname: J. Antoni
  orcidid: 0000-0003-1622-0350
  surname: Ramos-Quiroga
  fullname: Ramos-Quiroga, J. Antoni
  organization: Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Catalonia, Spain
– sequence: 62
  givenname: Arnt
  orcidid: 0000-0002-7715-5209
  surname: Schellekens
  fullname: Schellekens, Arnt
  organization: Radboud University Medical Centre, Donders Institute for Brain, Cognition, and Behavior, Department of Psychiatry, Nijmegen, the Netherlands
– sequence: 63
  givenname: Anouk
  surname: Scheres
  fullname: Scheres, Anouk
  organization: Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands
– sequence: 64
  givenname: Renata
  surname: Schoeman
  fullname: Schoeman, Renata
  organization: University of Stellenbosch Business School, Cape Town, South Africa
– sequence: 65
  givenname: Julie B.
  orcidid: 0000-0003-0257-1651
  surname: Schweitzer
  fullname: Schweitzer, Julie B.
  organization: Department of Psychiatry and Behavioral Sciences and the MIND Institute, University of California, Davis, Sacramento, CA, USA
– sequence: 66
  givenname: Henal
  surname: Shah
  fullname: Shah, Henal
  organization: Topiwala National Medical College & BYL Nair Ch. Hospital, Mumbai, India
– sequence: 67
  givenname: Mary V.
  orcidid: 0000-0002-3153-9610
  surname: Solanto
  fullname: Solanto, Mary V.
  organization: The Zucker School of Medicine at Hofstra-Northwell, Northwell Health, Hemstead, NY, USA
– sequence: 68
  givenname: Edmund
  surname: Sonuga-Barke
  fullname: Sonuga-Barke, Edmund
  organization: Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK
– sequence: 69
  givenname: César
  surname: Soutullo
  fullname: Soutullo, César
  organization: American Professional Society of ADHD and Related Disorders (APSARD), USA
– sequence: 70
  givenname: Hans-Christoph
  surname: Steinhausen
  fullname: Steinhausen, Hans-Christoph
  organization: University of Zurich, CH, Switzerland
– sequence: 71
  givenname: James M.
  surname: Swanson
  fullname: Swanson, James M.
  organization: Department of Pediatrics, University of California Irvine, Irvine, CA, USA
– sequence: 72
  givenname: Anita
  surname: Thapar
  fullname: Thapar, Anita
  organization: Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Wales, UK
– sequence: 73
  givenname: Gail
  surname: Tripp
  fullname: Tripp, Gail
  organization: Human Developmental Neurobiology Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan
– sequence: 74
  givenname: Geurt
  surname: van de Glind
  fullname: van de Glind, Geurt
  organization: Hogeschool van Utrecht/University of Applied Sciences, Utrecht, the Netherlands
– sequence: 75
  givenname: Wim
  surname: van den Brink
  fullname: van den Brink, Wim
  organization: Amsterdam University Medical Centers, Academic Medical Center, Amsterdam, the Netherlands
– sequence: 76
  givenname: Saskia
  orcidid: 0000-0003-2771-0187
  surname: Van der Oord
  fullname: Van der Oord, Saskia
  organization: Psychology and Educational Sciences, KU Leuven, Leuven, Belgium
– sequence: 77
  givenname: Andre
  surname: Venter
  fullname: Venter, Andre
  organization: University of the Free State, Bloemfontein, South Africa
– sequence: 78
  givenname: Benedetto
  surname: Vitiello
  fullname: Vitiello, Benedetto
  organization: University of Torino, Torino, Italy
– sequence: 79
  givenname: Susanne
  surname: Walitza
  fullname: Walitza, Susanne
  organization: Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland
– sequence: 80
  givenname: Yufeng
  surname: Wang
  fullname: Wang, Yufeng
  organization: Asian Federation of ADHD, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33549739$$D View this record in MEDLINE/PubMed
https://hal.science/hal-03662608$$DView record in HAL
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-89420$$DView record from Swedish Publication Index
http://kipublications.ki.se/Default.aspx?queryparsed=id:147277196$$DView record from Swedish Publication Index
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Keywords ADHD
Brain
Treatment
Outcome
Genetics
Diagnosis
Course
Language English
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Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.
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  start-page: 1657
  year: 2018
  ident: 10.1016/j.neubiorev.2021.01.022_bib0090
  article-title: Overuse of methylphenidate: an analysis of Swedish pharmacy dispensing data
  publication-title: Clin. Epidemiol.
  doi: 10.2147/CLEP.S178638
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Snippet •ADHD occurs in 5.9 % of youth and 2.5 % of adults.•Most cases of ADHD are caused by the combined effects of many genetic and environmental risks.•There are...
Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated...
Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we...
BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we...
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SubjectTerms ADHD
Attention Deficit Disorder with Hyperactivity
Attention Deficit Disorder with Hyperactivity - therapy
Brain
Course
Diagnosis
Genetics
Humans
Life Sciences
Meta-Analysis as Topic
Network Meta-Analysis
Outcome
Publication Bias
Treatment
Title The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder
URI https://dx.doi.org/10.1016/j.neubiorev.2021.01.022
https://www.ncbi.nlm.nih.gov/pubmed/33549739
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https://pubmed.ncbi.nlm.nih.gov/PMC8328933
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-89420
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Volume 128
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