Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis

• Published in: Allergology International Vol. 58; no. 3; pp. 373 - 382
• Main Authors: Hirano, Toru, Kawai, Mari, Arimitsu, Junsuke, Ogawa, Masako, Kuwahara, Yusuke, Hagihara, Keisuke, Shima, Yoshihito, Narazaki, Masashi, Ogata, Atsushi, Koyanagi, Mihoko, Kai, Tomoko, Shimizu, Ryosuke, Moriwaki, Masamitsu, Suzuki, Yukio, Ogino, Satoshi, Kawase, Ichiro, Tanaka, Toshio
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 2009; JAPANESE SOCIETY OF ALLERGOLOGY; Elsevier
• Subjects: Adult; Allergens - adverse effects; Anti-Allergic Agents - chemistry; Anti-Allergic Agents - therapeutic use; Conjunctivitis, Allergic - etiology; Conjunctivitis, Allergic - prevention & control; Cryptomeria - adverse effects; Cryptomeria japonica; diet therapy; Double-Blind Method; Female; flavonoid; Flavonoids - chemistry; Flavonoids - therapeutic use; Humans; Japanese cedar pollen; Male; Pollen - adverse effects; pollinosis; Pruritus - etiology; Pruritus - prevention & control; quercetin; Quercetin - analogs & derivatives; Quercetin - chemistry; Quercetin - therapeutic use; Rhinitis, Allergic, Seasonal - drug therapy; Rhinitis, Allergic, Seasonal - etiology; Tears - drug effects; Japanese cedar pollen; quercetin; flavonoid; pollinosis; diet therapy

Flavonoids are nutrients that exert anti-allergic effects. We investigated the preventative effect of enzymatically modified isoquercitrin (EMIQ), a flavonoid, to relieve the symptoms of Japanese cedar pollinosis. In a parallel-group, double-blind placebo-controlled study design, 24 subjects with Ja...