The Effects of Aging and Physical Activity on Doppler Measures of Diastolic Function
Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in...
Saved in:
| Published in | The American journal of cardiology Vol. 99; no. 12; pp. 1629 - 1636 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York, NY
Elsevier Inc
15.06.2007
Elsevier Elsevier Limited |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0002-9149 1879-1913 |
| DOI | 10.1016/j.amjcard.2007.01.050 |
Cover
Loading…
| Abstract | Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), −15 and −30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI E
mean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p <0.001), TDI E
mean (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI E
mean was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. |
|---|---|
| AbstractList | Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), −15 and −30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI Emean ), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p <0.001), TDI Emean (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI Emean was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), -15 and -30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI Emean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p <0.001), TDI Emean (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI Emean was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), −15 and −30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI E mean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p <0.001), TDI E mean (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI E mean was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), -15 and -30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (...), and propagation velocity of mitral inflow. Aging resulted in a decrease in EIA ratio (p <0.001), ... (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. ... was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. (ProQuest-CSA LLC: ... denotes formulae/symbols omitted.) Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70 ± 4 years) and 12 fit Masters athlete (68 ± 3 years) seniors were recruited. Twelve young healthy (32 ± 9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), –15 and –30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI E mean ), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p <0.001), TDI E mean (p <0.001), and propagation velocity of mitral inflow (p <0.001) and an increase in IVRT (p = 0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p = 0.212), IVRT (p = 0.546), or propagation velocity of mitral inflow (p = 1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI E mean was higher in fit versus sedentary seniors at baseline (p = 0.012) and during maximal lower body negative pressure (p = 0.036), but not during saline solution infusion (p = 0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70+/-4 years) and 12 fit Masters athlete (68+/-3 years) seniors were recruited. Twelve young healthy (32+/-9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), -15 and -30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI Emean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p<0.001), TDI Emean (p<0.001), and propagation velocity of mitral inflow (p<0.001) and an increase in IVRT (p=0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p=0.212), IVRT (p=0.546), or propagation velocity of mitral inflow (p=1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI Emean was higher in fit versus sedentary seniors at baseline (p=0.012) and during maximal lower body negative pressure (p=0.036), but not during saline solution infusion (p=0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning.Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70+/-4 years) and 12 fit Masters athlete (68+/-3 years) seniors were recruited. Twelve young healthy (32+/-9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), -15 and -30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI Emean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p<0.001), TDI Emean (p<0.001), and propagation velocity of mitral inflow (p<0.001) and an increase in IVRT (p=0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p=0.212), IVRT (p=0.546), or propagation velocity of mitral inflow (p=1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI Emean was higher in fit versus sedentary seniors at baseline (p=0.012) and during maximal lower body negative pressure (p=0.036), but not during saline solution infusion (p=0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging process or reflect a cardiac adaptation to a more sedentary lifestyle. It was hypothesized that healthy, but sedentary, aging would result in slowing of diastolic filling and myocardial relaxation, whereas lifelong endurance training would prevent such changes. Doppler data were measured in young subjects and sedentary and fit seniors across a broad range of loading conditions. Thirteen sedentary healthy (70+/-4 years) and 12 fit Masters athlete (68+/-3 years) seniors were recruited. Twelve young healthy (32+/-9 years) subjects were used for comparison. Pulmonary capillary wedge pressure and Doppler variables were measured at the 6 loading conditions of baseline (twice), -15 and -30 mm Hg lower body negative pressure, and 2 levels of saline solution infusion. Doppler variables consisted of early and late mitral inflow velocity (E/A) ratio, isovolumetric relaxation time (IVRT), tissue Doppler velocities (TDI Emean), and propagation velocity of mitral inflow. Aging resulted in a decrease in E/A ratio (p<0.001), TDI Emean (p<0.001), and propagation velocity of mitral inflow (p<0.001) and an increase in IVRT (p=0.001). Lifelong endurance training did not completely prevent the changes in E/A ratio (p=0.212), IVRT (p=0.546), or propagation velocity of mitral inflow (p=1.00). Fit seniors were able to achieve E/A ratios of 1.0 during baseline and saline solution infusion. TDI Emean was higher in fit versus sedentary seniors at baseline (p=0.012) and during maximal lower body negative pressure (p=0.036), but not during saline solution infusion (p=0.493). In conclusion, age-associated abnormalities in Doppler measures of myocardial filling and relaxation are only partially minimized by lifelong endurance training and therefore may be more specific to the aging process than secondary to years of deconditioning. |
| Author | Palmer, Dean Greenberg, Neil L. Fu, Qi Levine, Benjamin D. Prasad, Anand Popovic, Zoran B. Garcia, Mario J. Dijk, Erika Thomas, James D. Arbab-Zadeh, Armin |
| AuthorAffiliation | b Cleveland Clinic Foundation, Cleveland, Ohio a Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas c Johns Hopkins University, Baltimore, Maryland d Department of Integrative Physiology, University Medical Center, Nijmegen, The Netherlands |
| AuthorAffiliation_xml | – name: d Department of Integrative Physiology, University Medical Center, Nijmegen, The Netherlands – name: a Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas – name: b Cleveland Clinic Foundation, Cleveland, Ohio – name: c Johns Hopkins University, Baltimore, Maryland |
| Author_xml | – sequence: 1 givenname: Anand surname: Prasad fullname: Prasad, Anand organization: Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas – sequence: 2 givenname: Zoran B. surname: Popovic fullname: Popovic, Zoran B. organization: Cleveland Clinic Foundation, Cleveland, Ohio – sequence: 3 givenname: Armin surname: Arbab-Zadeh fullname: Arbab-Zadeh, Armin organization: Johns Hopkins University, Baltimore, Maryland – sequence: 4 givenname: Qi surname: Fu fullname: Fu, Qi organization: Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas – sequence: 5 givenname: Dean surname: Palmer fullname: Palmer, Dean organization: Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas – sequence: 6 givenname: Erika surname: Dijk fullname: Dijk, Erika organization: Department of Integrative Physiology, University Medical Center, Nijmegen, The Netherlands – sequence: 7 givenname: Neil L. surname: Greenberg fullname: Greenberg, Neil L. organization: Cleveland Clinic Foundation, Cleveland, Ohio – sequence: 8 givenname: Mario J. surname: Garcia fullname: Garcia, Mario J. organization: Cleveland Clinic Foundation, Cleveland, Ohio – sequence: 9 givenname: James D. surname: Thomas fullname: Thomas, James D. organization: Cleveland Clinic Foundation, Cleveland, Ohio – sequence: 10 givenname: Benjamin D. surname: Levine fullname: Levine, Benjamin D. email: benjaminlevine@texashealth.org organization: Institute for Exercise and Environmental Medicine, Presbyterian Hospital and University of Texas Southwestern Medical Center, Dallas, Texas |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20282407$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/17560865$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkm-r0zAYxYNc8e5e_QhKEfTd5pOmTRvEK-P-UeGKgvN1SNOnW2aXzKQd7Nubujl1IPNVKf2d04dzzgU5s84iIU8pTChQ_mo5UaulVr6epADFBOgEcnhARrQsxJgKys7ICADSsaCZOCcXISzjK6U5f0TOaZFzKHk-IrPZApPbpkHdhcQ1yXRu7DxRtk4-L7bBaNUmU92Zjem2ibPJjVuvW_TJR1Sh9_hTcmNU6FxrdHLX28g6-5g8bFQb8Mn-eUm-3t3Ort-P7z-9-3A9vR9rXtJuXKNuGK-grllBIU0zLLVQJa1UUwnNdMo5INdYaYEVy_Jc0JJVZYWioVphwS7J1c533VcrrDXazqtWrr1ZKb-VThn59xdrFnLuNjL-jzNeRoOXewPvvvcYOrkyQWPbKouuD7IATllWiJMgFUVMlvMIPj8Cl673NqYgUwaMi1hehJ79effh4F-1RODFHlAhVtB4ZbUJBy6FtEwzGALId5z2LgSPzW8rkMNM5FLuZyKHmUigMs4k6l4f6bTp1FBdjMm0J9Vvd2qM3W4Mehm0QauxNj7uSNbOnHS4OnLQrbHD2r7hFsMhMipDKkF-GYY87BgKgCwXQ8xv_m3wHwf8AM9NBW8 |
| CODEN | AJCDAG |
| CitedBy_id | crossref_primary_10_1007_s40279_019_01252_0 crossref_primary_10_1016_j_amjcard_2011_04_025 crossref_primary_10_1249_MSS_0b013e318172cf10 crossref_primary_10_2174_1874325001812010261 crossref_primary_10_1371_journal_pone_0210277 crossref_primary_10_1113_expphysiol_2012_067488 crossref_primary_10_1016_j_ahj_2016_12_006 crossref_primary_10_1111_echo_14975 crossref_primary_10_1016_j_jacc_2014_04_082 crossref_primary_10_1007_s11357_015_9816_7 crossref_primary_10_1152_japplphysiol_00089_2013 crossref_primary_10_1161_JAHA_121_023189 crossref_primary_10_1002_phy2_180 crossref_primary_10_1002_uog_23614 crossref_primary_10_1038_s41598_022_13802_0 crossref_primary_10_1161_CIRCIMAGING_111_968131 crossref_primary_10_1016_j_cardfail_2011_07_003 crossref_primary_10_1007_s10554_013_0246_2 crossref_primary_10_1139_H08_078 crossref_primary_10_1161_CIRCULATIONAHA_121_054117 crossref_primary_10_1016_j_exger_2017_05_016 crossref_primary_10_1111_j_1748_1716_2012_02430_x crossref_primary_10_1590_1517_869220172302158989 crossref_primary_10_1152_ajpregu_00028_2014 crossref_primary_10_1152_japplphysiol_00342_2013 crossref_primary_10_1007_s00392_017_1133_y crossref_primary_10_1093_eurheartj_ehp084 crossref_primary_10_1161_CIRCRESAHA_115_305250 crossref_primary_10_1161_CIRCIMAGING_108_813857 crossref_primary_10_1007_s12410_013_9223_3 crossref_primary_10_12659_MSM_883215 crossref_primary_10_1161_CIRCHEARTFAILURE_109_867044 crossref_primary_10_1371_journal_pone_0158302 crossref_primary_10_1080_17461390902763391 crossref_primary_10_1016_j_ijchv_2014_08_007 crossref_primary_10_1111_j_1755_5922_2010_00133_x crossref_primary_10_1161_CIRCULATIONAHA_118_037615 crossref_primary_10_14814_phy2_70144 crossref_primary_10_1016_j_echo_2019_10_009 crossref_primary_10_3390_jcm13247593 crossref_primary_10_14814_phy2_15129 crossref_primary_10_1007_s10554_015_0592_3 crossref_primary_10_3389_fcvm_2023_1285206 crossref_primary_10_1016_j_exger_2012_04_006 crossref_primary_10_3109_14017431_2012_660192 crossref_primary_10_1016_j_ultrasmedbio_2009_01_009 crossref_primary_10_1113_JP274172 crossref_primary_10_1249_JES_0000000000000247 crossref_primary_10_1016_S2213_8587_19_30119_6 crossref_primary_10_1152_japplphysiol_00798_2022 crossref_primary_10_1161_CIRCHEARTFAILURE_109_876649 crossref_primary_10_23736_S2724_5683_20_05442_0 crossref_primary_10_1111_j_1748_1716_2010_02081_x crossref_primary_10_1093_eurjhf_hfr088 crossref_primary_10_1161_CIRCEP_117_005598 crossref_primary_10_1113_jphysiol_2007_143651 crossref_primary_10_1016_j_echo_2014_07_007 crossref_primary_10_1007_s12350_019_01756_2 crossref_primary_10_1152_japplphysiol_00858_2006 crossref_primary_10_1161_CIRCIMAGING_110_960575 crossref_primary_10_1530_ERP_17_0082 crossref_primary_10_7556_jaoa_2015_089 crossref_primary_10_1152_japplphysiol_00420_2011 crossref_primary_10_1007_s00421_010_1534_3 crossref_primary_10_3389_fcvm_2018_00127 crossref_primary_10_1371_journal_pone_0266951 crossref_primary_10_1161_CIRCULATIONAHA_110_973784 crossref_primary_10_1016_j_jcct_2010_03_011 crossref_primary_10_1556_APhysiol_100_2013_1_1 crossref_primary_10_1016_j_arr_2018_04_007 crossref_primary_10_1113_expphysiol_2014_083014 crossref_primary_10_1139_apnm_2013_0414 crossref_primary_10_1371_journal_pone_0271628 crossref_primary_10_1007_s00421_009_1233_0 crossref_primary_10_1152_ajpheart_00142_2012 crossref_primary_10_1007_s00380_011_0122_8 crossref_primary_10_1016_j_jcmg_2023_09_003 crossref_primary_10_1113_jphysiol_2012_233858 crossref_primary_10_1111_echo_12759 crossref_primary_10_1111_sms_12153 crossref_primary_10_1007_s10554_019_01665_y crossref_primary_10_1249_MSS_0b013e318293b019 crossref_primary_10_1016_j_jacc_2014_03_062 crossref_primary_10_1136_bjsm_2007_039941 crossref_primary_10_1016_j_ihj_2017_02_006 crossref_primary_10_1016_j_jchf_2014_01_004 crossref_primary_10_1152_ajpregu_00151_2014 crossref_primary_10_1113_jphysiol_2009_170100 crossref_primary_10_1016_j_echo_2017_11_009 crossref_primary_10_1007_s00421_013_2773_x crossref_primary_10_1291_hypres_31_1573 crossref_primary_10_1038_sc_2017_30 crossref_primary_10_1002_ajim_20600 crossref_primary_10_1113_EP088834 crossref_primary_10_1016_j_eurger_2014_01_007 crossref_primary_10_1152_ajpregu_00099_2010 crossref_primary_10_1016_j_ahj_2014_10_017 crossref_primary_10_1016_j_amjcard_2009_05_066 crossref_primary_10_14814_phy2_13145 crossref_primary_10_1249_MSS_0b013e3181c81604 crossref_primary_10_3390_ani12010073 crossref_primary_10_1152_ajpheart_01069_2008 crossref_primary_10_1093_eurheartj_ehw121 crossref_primary_10_1016_j_pcad_2012_01_006 crossref_primary_10_1016_j_echo_2007_08_006 crossref_primary_10_1096_fj_10_172924 crossref_primary_10_1016_j_jsams_2014_07_005 crossref_primary_10_14814_phy2_12330 crossref_primary_10_1152_ajpheart_00911_2014 crossref_primary_10_2478_fzm_2022_0022 crossref_primary_10_1152_ajpheart_00511_2011 crossref_primary_10_1161_CIRCHEARTFAILURE_113_001420 crossref_primary_10_1016_j_echo_2012_05_018 crossref_primary_10_1002_clc_23369 crossref_primary_10_1152_ajpheart_00987_2009 crossref_primary_10_1038_nrcardio_2014_83 crossref_primary_10_1161_CIRCULATIONAHA_110_981571 |
| Cites_doi | 10.1016/0002-9149(87)91136-2 10.1016/0002-9149(91)90015-D 10.1016/0735-1097(95)00434-3 10.1016/S0735-1097(99)00503-3 10.1016/S0008-6363(00)00003-1 10.1249/00005768-199311000-00007 10.1161/01.CIR.0000142863.71285.74 10.1016/S0735-1097(97)88335-0 10.1161/01.HYP.0000168053.34306.d4 10.1042/CS20030204 10.1161/01.RES.67.4.871 10.1152/ajpheart.2000.279.6.H2994 10.1001/jama.288.17.2144 10.1016/S0733-8651(05)70159-4 10.1161/01.CIR.96.2.517 10.1016/S0047-6374(01)00296-2 10.1161/01.CIR.84.3.1016 10.1152/ajpheart.00902.2005 10.1016/0002-8703(92)90416-S 10.1016/S0735-1097(87)80273-5 10.1016/S0002-9149(02)03433-1 10.1016/S0008-6363(02)00341-3 10.1161/01.CIR.5.3.321 10.1001/jama.1995.03520410065028 10.1093/cvr/23.8.723 10.1161/01.CIR.0000048894.99865.02 10.1016/S0002-9149(99)00499-3 10.1007/s004210100447 |
| ContentType | Journal Article |
| Copyright | 2007 Elsevier Inc. Elsevier Inc. 2008 INIST-CNRS Copyright Elsevier Sequoia S.A. Jun 15, 2007 2007 Elsevier Inc. All rights reserved. 2007 |
| Copyright_xml | – notice: 2007 Elsevier Inc. – notice: Elsevier Inc. – notice: 2008 INIST-CNRS – notice: Copyright Elsevier Sequoia S.A. Jun 15, 2007 – notice: 2007 Elsevier Inc. All rights reserved. 2007 |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7TS 8FD FR3 K9. M7Z NAPCQ P64 7X8 5PM |
| DOI | 10.1016/j.amjcard.2007.01.050 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Physical Education Index Technology Research Database Engineering Research Database ProQuest Health & Medical Complete (Alumni) Biochemistry Abstracts 1 Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Technology Research Database Biochemistry Abstracts 1 ProQuest Health & Medical Complete (Alumni) Engineering Research Database Physical Education Index Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | Physical Education Index Nursing & Allied Health Premium MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1879-1913 |
| EndPage | 1636 |
| ExternalDocumentID | PMC3716368 1287537351 17560865 20282407 10_1016_j_amjcard_2007_01_050 S0002914907004596 1_s2_0_S0002914907004596 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NIA NIH HHS grantid: R01 AG017479 – fundername: NIA NIH HHS grantid: AG17479-02 – fundername: National Institute on Aging : NIA grantid: R01 AG017479 || AG |
| GroupedDBID | --- --K --M .1- .55 .FO .GJ .~1 0R~ 123 1B1 1CY 1P~ 1RT 1~. 1~5 23M 3O- 4.4 457 4G. 53G 5RE 5VS 6J9 7-5 71M 7RV 7X7 88E 8FI 8FJ 8G5 8P~ 9JM AABNK AAEDT AAEDW AAIKJ AAKOC AALRI AAQFI AAQQT AAQXK AATTM AAWTL AAXKI AAXUO AAYWO ABBQC ABFNM ABJNI ABLJU ABMAC ABMZM ABOCM ABPPZ ABUWG ABWVN ABXDB ACDAQ ACGFO ACGFS ACIEU ACIUM ACIWK ACPRK ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADFRT ADMUD ADNMO ADUKH AEBSH AEIPS AEKER AENEX AEUPX AEVXI AFFNX AFJKZ AFKRA AFPUW AFRAH AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGYEJ AHHHB AHMBA AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN AZQEC BENPR BKEYQ BKOJK BKOMP BLXMC BNPGV BPHCQ BVXVI CCPQU CS3 DWQXO EBS EFJIC EFKBS EJD EMOBN EO9 EP2 EP3 EX3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN FYUFA G-2 G-Q GBLVA GNUQQ GUQSH HEB HMCUK HMK HMO HVGLF HZ~ IH2 IHE J1W J5H K-O KOM L7B M1P M29 M2O M41 MO0 N9A NAPCQ O-L O9- OA. OAUVE OHT OL~ OVD OZT P-8 P-9 P2P PC. PHGZM PHGZT PJZUB PPXIY PQQKQ PROAC PSQYO PUEGO Q38 R2- ROL RPZ SAE SDF SDG SEL SES SJN SPCBC SSH SSZ SV3 T5K TEORI TWZ UKHRP UNMZH UV1 WH7 WOW WUQ X7M XPP YFH YOC YQJ YYP YZZ Z5R ZGI ZXP ~G- 3V. AACTN AAYOK AFCTW AFKWA AJOXV ALIPV AMFUW PKN RIG AAIAV ABLVK ABYKQ AHPSJ AJBFU EFLBG LCYCR ZA5 AAYXX AGRNS CITATION IQODW CGR CUY CVF ECM EIF NPM 7TS 8FD FR3 K9. M7Z P64 7X8 5PM |
| ID | FETCH-LOGICAL-c681t-decf36b0dd3710224e8c9a81bafb9c3c2660e6cebc9eb34559183b8be9f1cae73 |
| IEDL.DBID | .~1 |
| ISSN | 0002-9149 |
| IngestDate | Thu Aug 21 18:02:39 EDT 2025 Thu Sep 04 20:58:13 EDT 2025 Thu Sep 04 23:55:45 EDT 2025 Sat Jul 26 02:38:55 EDT 2025 Mon Jul 21 05:38:29 EDT 2025 Mon Jul 21 09:10:36 EDT 2025 Thu Apr 24 23:08:14 EDT 2025 Tue Jul 01 01:52:31 EDT 2025 Fri Feb 23 02:21:53 EST 2024 Sun Feb 23 10:18:59 EST 2025 Tue Aug 26 18:33:33 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | Sonography Doppler ultrasound study Physical exercise Cardiac performance Diastole Ageing Circulatory system Cardiology |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c681t-decf36b0dd3710224e8c9a81bafb9c3c2660e6cebc9eb34559183b8be9f1cae73 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| PMID | 17560865 |
| PQID | 230369101 |
| PQPubID | 41200 |
| PageCount | 8 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_3716368 proquest_miscellaneous_70613479 proquest_miscellaneous_19715666 proquest_journals_230369101 pubmed_primary_17560865 pascalfrancis_primary_20282407 crossref_primary_10_1016_j_amjcard_2007_01_050 crossref_citationtrail_10_1016_j_amjcard_2007_01_050 elsevier_sciencedirect_doi_10_1016_j_amjcard_2007_01_050 elsevier_clinicalkeyesjournals_1_s2_0_S0002914907004596 elsevier_clinicalkey_doi_10_1016_j_amjcard_2007_01_050 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2007-06-15 |
| PublicationDateYYYYMMDD | 2007-06-15 |
| PublicationDate_xml | – month: 06 year: 2007 text: 2007-06-15 day: 15 |
| PublicationDecade | 2000 |
| PublicationPlace | New York, NY |
| PublicationPlace_xml | – name: New York, NY – name: United States – name: New York |
| PublicationTitle | The American journal of cardiology |
| PublicationTitleAlternate | Am J Cardiol |
| PublicationYear | 2007 |
| Publisher | Elsevier Inc Elsevier Elsevier Limited |
| Publisher_xml | – name: Elsevier Inc – name: Elsevier – name: Elsevier Limited |
| References | Kass (bib17) 2005; 46 Levine, Zuckerman, Pawelczyk (bib19) 1997; 96 Arbab-Zadeh, Dijk, Prasad, Fu, Torres, Zhang, Thomas, Palmer, Levine (bib4) 2004; 110 Nikolic, Feneley, Pajaro, Rankin, Yellin (bib18) 1995; 268 Sohn, Chai, Lee, Kim, Kim, Oh, Lee, Park, Choi, Seo, Lee (bib7) 1997; 30 Garcia, Smedira, Greenberg, Main, Firstenberg, Odabashian, Thomas (bib14) 2000; 35 Tate, Taffet, Hudson, Blaylock, McBride, Michael (bib29) 1990; 258 Anversa, Palackal, Sonnenblick, Olivetti, Meggs, Capasso (bib22) 1990; 67 Jin, Yang, Li, Lu, Ryan, Ogasawara, Van Peborgh, Paoni (bib27) 2000; 279 Choong, Herrmann, Weyman, Fifer (bib2) 1987; 10 Tate, Hamra, Shin, Taffet, McBride, Entman (bib28) 1993; 25 Garcia, Rodriguez, Ares, Griffin, Thomas, Klein (bib12) 1996; 27 Thomas, Cotter, Li, McCormick, Gosselin (bib26) 2001; 85 Kitzman, Little, Brubaker, Anderson, Hundley, Marburger, Brosnihan, Morgan, Stewart (bib30) 2002; 288 Levine, Lane, Buckey, Friedman, Blomqvist (bib5) 1991; 84 Appleton, Firstenberg, Garcia, Thomas (bib9) 2000; 18 Yamamoto, Masuyama, Sakata, Nishikawa, Mano, Yoshida, Miwa, Sugawara, Yamaguchi, Ookawara, Suzuki, Hori (bib20) 2002; 55 Rivas-Gotz, Manolios, Thohan, Nagueh (bib8) 2003; 91 Nagueh, Rao, Soto, Middleton, Khoury (bib13) 2004; 106 Fleg, Shapiro, O’Connor, Taube, Goldberg, Lakatta (bib10) 1995; 273 Lakatta (bib23) 2003; 107 Eghbali, Eghbali, Robinson, Seifter, Blumenfeld (bib24) 1989; 23 Li, McTiernan, Feldman (bib21) 2000; 46 Thomas, Flachskampf, Chen, Guererro, Picard, Levine, Weyman (bib11) 1992; 124 Wiggers (bib6) 1952; 5 Burgess, McCrea, Hedrick (bib25) 2001; 122 Palka, Lange, Nihoyannopoulos (bib3) 1999; 84 Bryg, Williams, Labovitz (bib1) 1987; 59 Popovic, Prasad, Garcia, Arbab-Zadeh, Borowski, Dijk, Greenberg, Levine, Thomas (bib15) 2006; 290 Johannessen, Cerqueira, Veith, Stratton (bib16) 1991; 67 Rivas-Gotz (10.1016/j.amjcard.2007.01.050_bib8) 2003; 91 Wiggers (10.1016/j.amjcard.2007.01.050_bib6) 1952; 5 Thomas (10.1016/j.amjcard.2007.01.050_bib26) 2001; 85 Palka (10.1016/j.amjcard.2007.01.050_bib3) 1999; 84 Levine (10.1016/j.amjcard.2007.01.050_bib5) 1991; 84 Popovic (10.1016/j.amjcard.2007.01.050_bib15) 2006; 290 Arbab-Zadeh (10.1016/j.amjcard.2007.01.050_bib4) 2004; 110 Yamamoto (10.1016/j.amjcard.2007.01.050_bib20) 2002; 55 Fleg (10.1016/j.amjcard.2007.01.050_bib10) 1995; 273 Jin (10.1016/j.amjcard.2007.01.050_bib27) 2000; 279 Tate (10.1016/j.amjcard.2007.01.050_bib28) 1993; 25 Johannessen (10.1016/j.amjcard.2007.01.050_bib16) 1991; 67 Thomas (10.1016/j.amjcard.2007.01.050_bib11) 1992; 124 Nikolic (10.1016/j.amjcard.2007.01.050_bib18) 1995; 268 Eghbali (10.1016/j.amjcard.2007.01.050_bib24) 1989; 23 Tate (10.1016/j.amjcard.2007.01.050_bib29) 1990; 258 Burgess (10.1016/j.amjcard.2007.01.050_bib25) 2001; 122 Bryg (10.1016/j.amjcard.2007.01.050_bib1) 1987; 59 Choong (10.1016/j.amjcard.2007.01.050_bib2) 1987; 10 Kitzman (10.1016/j.amjcard.2007.01.050_bib30) 2002; 288 Sohn (10.1016/j.amjcard.2007.01.050_bib7) 1997; 30 Anversa (10.1016/j.amjcard.2007.01.050_bib22) 1990; 67 Kass (10.1016/j.amjcard.2007.01.050_bib17) 2005; 46 Nagueh (10.1016/j.amjcard.2007.01.050_bib13) 2004; 106 Li (10.1016/j.amjcard.2007.01.050_bib21) 2000; 46 Garcia (10.1016/j.amjcard.2007.01.050_bib12) 1996; 27 Appleton (10.1016/j.amjcard.2007.01.050_bib9) 2000; 18 Garcia (10.1016/j.amjcard.2007.01.050_bib14) 2000; 35 Lakatta (10.1016/j.amjcard.2007.01.050_bib23) 2003; 107 Levine (10.1016/j.amjcard.2007.01.050_bib19) 1997; 96 12633827 - Am J Cardiol. 2003 Mar 15;91(6):780-4 3565286 - Am J Cardiol. 1987 Apr 15;59(9):971-4 10569664 - Am J Cardiol. 1999 Nov 1;84(9):1061-7 12413374 - JAMA. 2002 Nov 6;288(17):2144-50 1442500 - Am Heart J. 1992 Nov;124(5):1305-13 11557277 - Mech Ageing Dev. 2001 Oct;122(15):1739-56 1884438 - Circulation. 1991 Sep;84(3):1016-23 9247521 - J Am Coll Cardiol. 1997 Aug;30(2):474-80 11513311 - Eur J Appl Physiol. 2001 Jul;85(1-2):164-9 2145091 - Circ Res. 1990 Oct;67(4):871-85 15364801 - Circulation. 2004 Sep 28;110(13):1799-805 7715063 - JAMA. 1995 May 3;273(17):1371-5 12968949 - Clin Sci (Lond). 2004 Feb;106(2):147-54 8289611 - Med Sci Sports Exerc. 1993 Nov;25(11):1246-57 9244220 - Circulation. 1997 Jul 15;96(2):517-25 2598224 - Cardiovasc Res. 1989 Aug;23(8):723-9 2958532 - J Am Coll Cardiol. 1987 Oct;10(4):800-8 15911741 - Hypertension. 2005 Jul;46(1):185-93 11087257 - Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2994-3002 12551876 - Circulation. 2003 Jan 28;107(3):490-7 10773225 - Cardiovasc Res. 2000 May;46(2):214-24 1998284 - Am J Cardiol. 1991 Mar 1;67(6):520-6 8522683 - J Am Coll Cardiol. 1996 Jan;27(1):108-14 7864179 - Am J Physiol. 1995 Feb;268(2 Pt 2):H550-7 14905571 - Circulation. 1952 Mar;5(3):321-48 2137986 - Am J Physiol. 1990 Feb;258(2 Pt 2):H431-5 12062710 - Cardiovasc Res. 2002 Jul;55(1):76-82 10636281 - J Am Coll Cardiol. 2000 Jan;35(1):201-8 16284230 - Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1454-9 10986587 - Cardiol Clin. 2000 Aug;18(3):513-46, ix |
| References_xml | – volume: 85 start-page: 164 year: 2001 end-page: 169 ident: bib26 article-title: Exercise training attenuates aging-associated increases in collagen and collagen crosslinking of the left but not the right ventricle in the rat publication-title: Eur J Appl Physiol – volume: 96 start-page: 517 year: 1997 end-page: 525 ident: bib19 article-title: Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance publication-title: Circulation – volume: 46 start-page: 185 year: 2005 end-page: 193 ident: bib17 article-title: Ventricular arterial stiffening: integrating the pathophysiology publication-title: Hypertension – volume: 290 start-page: H1454 year: 2006 end-page: H1459 ident: bib15 article-title: Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness publication-title: Am J Physiol Heart Circ Physiol – volume: 124 start-page: 1305 year: 1992 end-page: 1313 ident: bib11 article-title: Isovolumic relaxation time varies predictably with its time constant and aortic and left atrial pressures: implications for the noninvasive evaluation of ventricular relaxation publication-title: Am Heart J – volume: 30 start-page: 474 year: 1997 end-page: 480 ident: bib7 article-title: Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function publication-title: J Am Coll Cardiol – volume: 279 start-page: H2994 year: 2000 end-page: H3002 ident: bib27 article-title: Effects of exercise training on cardiac function, gene expression, and apoptosis in rats publication-title: Am J Physiol Heart Circ Physiol – volume: 25 start-page: 1246 year: 1993 end-page: 1257 ident: bib28 article-title: Canine cardiac sarcoplasmic reticulum is not altered with endurance exercise training publication-title: Med Sci Sports Exerc – volume: 106 start-page: 147 year: 2004 end-page: 154 ident: bib13 article-title: Haemodynamic insights into the effects of ischaemia and cycle length on tissue Doppler-derived mitral annulus diastolic velocities publication-title: Clin Sci (Lond) – volume: 27 start-page: 108 year: 1996 end-page: 114 ident: bib12 article-title: Differentiation of constrictive pericarditis from restrictive cardiomyopathy: assessment of left ventricular diastolic velocities in longitudinal axis by Doppler tissue imaging publication-title: J Am Coll Cardiol – volume: 55 start-page: 76 year: 2002 end-page: 82 ident: bib20 article-title: Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart publication-title: Cardiovasc Res – volume: 107 start-page: 490 year: 2003 end-page: 497 ident: bib23 article-title: Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging publication-title: Circulation – volume: 18 start-page: 513 year: 2000 end-page: 546 ident: bib9 article-title: The echo-Doppler evaluation of left ventricular diastolic function publication-title: Cardiol Clin – volume: 91 start-page: 780 year: 2003 end-page: 784 ident: bib8 article-title: Impact of left ventricular ejection fraction on estimation of left ventricular filling pressures using tissue Doppler and flow propagation velocity publication-title: Am J Cardiol – volume: 10 start-page: 800 year: 1987 end-page: 808 ident: bib2 article-title: Preload dependence of Doppler-derived indexes of left ventricular diastolic function in humans publication-title: J Am Coll Cardiol – volume: 288 start-page: 2144 year: 2002 end-page: 2150 ident: bib30 article-title: Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure publication-title: JAMA – volume: 258 start-page: H431 year: 1990 end-page: H435 ident: bib29 article-title: Enhanced calcium uptake of cardiac sarcoplasmic reticulum in exercise-trained old rats publication-title: Am J Physiol – volume: 110 start-page: 1799 year: 2004 end-page: 1805 ident: bib4 article-title: Effect of aging and physical activity on left ventricular compliance publication-title: Circulation – volume: 46 start-page: 214 year: 2000 end-page: 224 ident: bib21 article-title: Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling publication-title: Cardiovasc Res – volume: 5 start-page: 321 year: 1952 end-page: 348 ident: bib6 article-title: The Henry Jackson memorial lecture: dynamics of ventricular contraction under abnormal conditions publication-title: Circulation – volume: 59 start-page: 971 year: 1987 end-page: 974 ident: bib1 article-title: Effect of aging on left ventricular diastolic filling in normal subjects publication-title: Am J Cardiol – volume: 84 start-page: 1061 year: 1999 end-page: 1067 ident: bib3 article-title: The effect of long-term training on age-related left ventricular changes by Doppler myocardial velocity gradient publication-title: Am J Cardiol – volume: 273 start-page: 1371 year: 1995 end-page: 1375 ident: bib10 article-title: Left ventricular diastolic filling performance in older male athletes publication-title: JAMA – volume: 23 start-page: 723 year: 1989 end-page: 729 ident: bib24 article-title: Collagen accumulation in heart ventricles as a function of growth and aging publication-title: Cardiovasc Res – volume: 122 start-page: 1739 year: 2001 end-page: 1756 ident: bib25 article-title: Age-associated changes in cardiac matrix and integrins publication-title: Mech Ageing Dev – volume: 67 start-page: 871 year: 1990 end-page: 885 ident: bib22 article-title: Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart publication-title: Circ Res – volume: 67 start-page: 520 year: 1991 end-page: 526 ident: bib16 article-title: Influence of sympathetic stimulation and parasympathetic withdrawal on Doppler echocardiographic left ventricular diastolic filling velocities in young normal subjects publication-title: Am J Cardiol – volume: 35 start-page: 201 year: 2000 end-page: 208 ident: bib14 article-title: Color M-mode Doppler flow propagation velocity is a preload insensitive index of left ventricular relaxation: animal and human validation publication-title: J Am Coll Cardiol – volume: 84 start-page: 1016 year: 1991 end-page: 1023 ident: bib5 article-title: Left ventricular pressure-volume and Frank-Starling relations in endurance athletes publication-title: Circulation – volume: 268 start-page: H550 year: 1995 end-page: H557 ident: bib18 article-title: Origin of regional pressure gradients in the left ventricle during early diastole publication-title: Am J Physiol – volume: 59 start-page: 971 year: 1987 ident: 10.1016/j.amjcard.2007.01.050_bib1 article-title: Effect of aging on left ventricular diastolic filling in normal subjects publication-title: Am J Cardiol doi: 10.1016/0002-9149(87)91136-2 – volume: 67 start-page: 520 year: 1991 ident: 10.1016/j.amjcard.2007.01.050_bib16 article-title: Influence of sympathetic stimulation and parasympathetic withdrawal on Doppler echocardiographic left ventricular diastolic filling velocities in young normal subjects publication-title: Am J Cardiol doi: 10.1016/0002-9149(91)90015-D – volume: 27 start-page: 108 year: 1996 ident: 10.1016/j.amjcard.2007.01.050_bib12 article-title: Differentiation of constrictive pericarditis from restrictive cardiomyopathy: assessment of left ventricular diastolic velocities in longitudinal axis by Doppler tissue imaging publication-title: J Am Coll Cardiol doi: 10.1016/0735-1097(95)00434-3 – volume: 35 start-page: 201 year: 2000 ident: 10.1016/j.amjcard.2007.01.050_bib14 article-title: Color M-mode Doppler flow propagation velocity is a preload insensitive index of left ventricular relaxation: animal and human validation publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(99)00503-3 – volume: 46 start-page: 214 year: 2000 ident: 10.1016/j.amjcard.2007.01.050_bib21 article-title: Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling publication-title: Cardiovasc Res doi: 10.1016/S0008-6363(00)00003-1 – volume: 25 start-page: 1246 year: 1993 ident: 10.1016/j.amjcard.2007.01.050_bib28 article-title: Canine cardiac sarcoplasmic reticulum is not altered with endurance exercise training publication-title: Med Sci Sports Exerc doi: 10.1249/00005768-199311000-00007 – volume: 110 start-page: 1799 year: 2004 ident: 10.1016/j.amjcard.2007.01.050_bib4 article-title: Effect of aging and physical activity on left ventricular compliance publication-title: Circulation doi: 10.1161/01.CIR.0000142863.71285.74 – volume: 30 start-page: 474 year: 1997 ident: 10.1016/j.amjcard.2007.01.050_bib7 article-title: Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(97)88335-0 – volume: 46 start-page: 185 year: 2005 ident: 10.1016/j.amjcard.2007.01.050_bib17 article-title: Ventricular arterial stiffening: integrating the pathophysiology publication-title: Hypertension doi: 10.1161/01.HYP.0000168053.34306.d4 – volume: 106 start-page: 147 year: 2004 ident: 10.1016/j.amjcard.2007.01.050_bib13 article-title: Haemodynamic insights into the effects of ischaemia and cycle length on tissue Doppler-derived mitral annulus diastolic velocities publication-title: Clin Sci (Lond) doi: 10.1042/CS20030204 – volume: 67 start-page: 871 year: 1990 ident: 10.1016/j.amjcard.2007.01.050_bib22 article-title: Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart publication-title: Circ Res doi: 10.1161/01.RES.67.4.871 – volume: 279 start-page: H2994 year: 2000 ident: 10.1016/j.amjcard.2007.01.050_bib27 article-title: Effects of exercise training on cardiac function, gene expression, and apoptosis in rats publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.2000.279.6.H2994 – volume: 288 start-page: 2144 year: 2002 ident: 10.1016/j.amjcard.2007.01.050_bib30 article-title: Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure publication-title: JAMA doi: 10.1001/jama.288.17.2144 – volume: 18 start-page: 513 year: 2000 ident: 10.1016/j.amjcard.2007.01.050_bib9 article-title: The echo-Doppler evaluation of left ventricular diastolic function publication-title: Cardiol Clin doi: 10.1016/S0733-8651(05)70159-4 – volume: 96 start-page: 517 year: 1997 ident: 10.1016/j.amjcard.2007.01.050_bib19 article-title: Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance publication-title: Circulation doi: 10.1161/01.CIR.96.2.517 – volume: 122 start-page: 1739 year: 2001 ident: 10.1016/j.amjcard.2007.01.050_bib25 article-title: Age-associated changes in cardiac matrix and integrins publication-title: Mech Ageing Dev doi: 10.1016/S0047-6374(01)00296-2 – volume: 84 start-page: 1016 year: 1991 ident: 10.1016/j.amjcard.2007.01.050_bib5 article-title: Left ventricular pressure-volume and Frank-Starling relations in endurance athletes publication-title: Circulation doi: 10.1161/01.CIR.84.3.1016 – volume: 290 start-page: H1454 year: 2006 ident: 10.1016/j.amjcard.2007.01.050_bib15 article-title: Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00902.2005 – volume: 268 start-page: H550 year: 1995 ident: 10.1016/j.amjcard.2007.01.050_bib18 article-title: Origin of regional pressure gradients in the left ventricle during early diastole publication-title: Am J Physiol – volume: 124 start-page: 1305 year: 1992 ident: 10.1016/j.amjcard.2007.01.050_bib11 article-title: Isovolumic relaxation time varies predictably with its time constant and aortic and left atrial pressures: implications for the noninvasive evaluation of ventricular relaxation publication-title: Am Heart J doi: 10.1016/0002-8703(92)90416-S – volume: 10 start-page: 800 year: 1987 ident: 10.1016/j.amjcard.2007.01.050_bib2 article-title: Preload dependence of Doppler-derived indexes of left ventricular diastolic function in humans publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(87)80273-5 – volume: 91 start-page: 780 year: 2003 ident: 10.1016/j.amjcard.2007.01.050_bib8 article-title: Impact of left ventricular ejection fraction on estimation of left ventricular filling pressures using tissue Doppler and flow propagation velocity publication-title: Am J Cardiol doi: 10.1016/S0002-9149(02)03433-1 – volume: 55 start-page: 76 year: 2002 ident: 10.1016/j.amjcard.2007.01.050_bib20 article-title: Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart publication-title: Cardiovasc Res doi: 10.1016/S0008-6363(02)00341-3 – volume: 5 start-page: 321 year: 1952 ident: 10.1016/j.amjcard.2007.01.050_bib6 article-title: The Henry Jackson memorial lecture: dynamics of ventricular contraction under abnormal conditions publication-title: Circulation doi: 10.1161/01.CIR.5.3.321 – volume: 273 start-page: 1371 year: 1995 ident: 10.1016/j.amjcard.2007.01.050_bib10 article-title: Left ventricular diastolic filling performance in older male athletes publication-title: JAMA doi: 10.1001/jama.1995.03520410065028 – volume: 23 start-page: 723 year: 1989 ident: 10.1016/j.amjcard.2007.01.050_bib24 article-title: Collagen accumulation in heart ventricles as a function of growth and aging publication-title: Cardiovasc Res doi: 10.1093/cvr/23.8.723 – volume: 107 start-page: 490 year: 2003 ident: 10.1016/j.amjcard.2007.01.050_bib23 article-title: Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging publication-title: Circulation doi: 10.1161/01.CIR.0000048894.99865.02 – volume: 84 start-page: 1061 year: 1999 ident: 10.1016/j.amjcard.2007.01.050_bib3 article-title: The effect of long-term training on age-related left ventricular changes by Doppler myocardial velocity gradient publication-title: Am J Cardiol doi: 10.1016/S0002-9149(99)00499-3 – volume: 85 start-page: 164 year: 2001 ident: 10.1016/j.amjcard.2007.01.050_bib26 article-title: Exercise training attenuates aging-associated increases in collagen and collagen crosslinking of the left but not the right ventricle in the rat publication-title: Eur J Appl Physiol doi: 10.1007/s004210100447 – volume: 258 start-page: H431 year: 1990 ident: 10.1016/j.amjcard.2007.01.050_bib29 article-title: Enhanced calcium uptake of cardiac sarcoplasmic reticulum in exercise-trained old rats publication-title: Am J Physiol – reference: 9247521 - J Am Coll Cardiol. 1997 Aug;30(2):474-80 – reference: 11087257 - Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2994-3002 – reference: 1884438 - Circulation. 1991 Sep;84(3):1016-23 – reference: 12413374 - JAMA. 2002 Nov 6;288(17):2144-50 – reference: 15364801 - Circulation. 2004 Sep 28;110(13):1799-805 – reference: 1998284 - Am J Cardiol. 1991 Mar 1;67(6):520-6 – reference: 2598224 - Cardiovasc Res. 1989 Aug;23(8):723-9 – reference: 10636281 - J Am Coll Cardiol. 2000 Jan;35(1):201-8 – reference: 7864179 - Am J Physiol. 1995 Feb;268(2 Pt 2):H550-7 – reference: 2958532 - J Am Coll Cardiol. 1987 Oct;10(4):800-8 – reference: 8289611 - Med Sci Sports Exerc. 1993 Nov;25(11):1246-57 – reference: 10773225 - Cardiovasc Res. 2000 May;46(2):214-24 – reference: 11557277 - Mech Ageing Dev. 2001 Oct;122(15):1739-56 – reference: 14905571 - Circulation. 1952 Mar;5(3):321-48 – reference: 1442500 - Am Heart J. 1992 Nov;124(5):1305-13 – reference: 9244220 - Circulation. 1997 Jul 15;96(2):517-25 – reference: 7715063 - JAMA. 1995 May 3;273(17):1371-5 – reference: 16284230 - Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1454-9 – reference: 12633827 - Am J Cardiol. 2003 Mar 15;91(6):780-4 – reference: 12968949 - Clin Sci (Lond). 2004 Feb;106(2):147-54 – reference: 15911741 - Hypertension. 2005 Jul;46(1):185-93 – reference: 11513311 - Eur J Appl Physiol. 2001 Jul;85(1-2):164-9 – reference: 2137986 - Am J Physiol. 1990 Feb;258(2 Pt 2):H431-5 – reference: 2145091 - Circ Res. 1990 Oct;67(4):871-85 – reference: 12062710 - Cardiovasc Res. 2002 Jul;55(1):76-82 – reference: 12551876 - Circulation. 2003 Jan 28;107(3):490-7 – reference: 3565286 - Am J Cardiol. 1987 Apr 15;59(9):971-4 – reference: 8522683 - J Am Coll Cardiol. 1996 Jan;27(1):108-14 – reference: 10986587 - Cardiol Clin. 2000 Aug;18(3):513-46, ix – reference: 10569664 - Am J Cardiol. 1999 Nov 1;84(9):1061-7 |
| SSID | ssj0001156 |
| Score | 2.2781055 |
| Snippet | Healthy aging results in changes in Doppler measures of diastolic function. It is unclear whether these alterations are a specific manifestation of the aging... |
| SourceID | pubmedcentral proquest pubmed pascalfrancis crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1629 |
| SubjectTerms | Adult Aged Aging Aging - physiology Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular system Clinical outcomes Compliance Coronary vessels Cross-Sectional Studies Diastole - physiology Echocardiography, Doppler, Color Echocardiography, Doppler, Pulsed Exercise - physiology Female Geriatrics Heart Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mitral Valve - physiology Ultrasonic investigative techniques Ventricular Function - physiology |
| Title | The Effects of Aging and Physical Activity on Doppler Measures of Diastolic Function |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0002914907004596 https://www.clinicalkey.es/playcontent/1-s2.0-S0002914907004596 https://dx.doi.org/10.1016/j.amjcard.2007.01.050 https://www.ncbi.nlm.nih.gov/pubmed/17560865 https://www.proquest.com/docview/230369101 https://www.proquest.com/docview/19715666 https://www.proquest.com/docview/70613479 https://pubmed.ncbi.nlm.nih.gov/PMC3716368 |
| Volume | 99 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF5VRUJICPHGFMIeuDrxY72PY5QShUeqCrVSb6t9WTgqdlSnV347s_HaIRBUxClSvKPYM7Oz38Qz3yD0XpMis4SnsSisjgmnOhYAzGOnnCuUpVRz35y8PKOLS_Lpqrg6QrO-F8aXVYbY38X0bbQO30yCNifrqvI9vkkmAOAnnqG9EJ52mxDm-fPHP3ZlHoB4aA-B_epdF89kNVbfVwYMEZgM03Hi2-8Pn08P16oFrZXduItDePT3sspfzqn5Y_QoAEw87Z7hCTpy9VN0fxleoT9DF-AYuOMsbnFT4qmfUoRVbfF5MBmemm6kBG5qfNoATHU3eNn9l7gVOa0UQMbryuA5nIress_R5fzDxWwRh9EKsaE83cTWmTKnOrE2Z1tSOceNUABhVamFyQ0c24mjxmkjINsmkHbA1tdcO1GmRjmWv0DHdVO7VwgX1KgkJ6xIrSO8JEJz0LPVNFPMGi4iRHqFShN4x_34i2vZF5itZLCDn4nJZJJKsEOExoPYuiPeuEuA9taSfVcpxEEJR8NdguyQoGvDbm5lKttMJvIPj4sQHyT3nPZffnS051DDM2Y-CYYsO0InvYfJ4UYyDzgA4KURejdchXjgX_Ko2jW3cK-C-ZSc_n0F8xCOMDDMy85fd_plgH85LUAje548LPBc5PtX6urblpMc3IjmlL_-f42coAd9LWZavEHHm5tb9xYA30aPtjt6hO5NZ1-_nPvPj58XZz8BsF1Ycg |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF6VIgESQrwxhXYPXJ34sc9j1BIFaCoOqdTbane9Fo6KE9Xpld_OrL12CAQVcbV3ZHtmduYb7zwQ-mAIzQoi0ljSwsREMBNLAOax085RXTBmhC9Onl-w2SX5fEWvDtBpXwvj0yqD7e9semutw5Vx4OZ4XVW-xjfJJAD8xHdop5LdQ_cJzblX7dGPbZ4HQB7WY2C_fFvGM16O9PelBUmEVobpKPH19_sd1OO1boBtZTfvYh8g_T2v8hdHNX2KngSEiSfdRzxDB65-jh7Mwxn6C7QAzcBd0-IGr0o88WOKsK4L_DXIDE9sN1MCr2p8tgKc6m7wvPuZ2JKcVRow43Vl8RTcohftS3Q5_bg4ncVhtkJsmUg3ceFsmTOTFEXO265yTlipAcPq0kibW_DbiWPWGSsh3CYQd8DeN8I4WaZWO56_Qof1qnZvEKbM6iQnnKaFI6Ik0gjgc2FYpnlhhYwQ6RmqbGg87udfXKs-w2ypghz8UEyuklSBHCI0GsjWXeeNuwhYLy3Vl5WCIVTgG-4i5PsIXRO2c6NS1WQqUX-oXITEQLmjtf_y0OMdhRq-MfNRMITZETrqNUwNL5J5xAEIL43QyXAXDII_5dG1W93Cu0ruY3L29xXcYzjCQTCvO33d8pcDABaMAkd2NHlY4JuR796pq29tU3JQI5Yz8fb_OXKCHs4W83N1_uniyxF61CdmpvQdOtzc3Lr3gP425rjd3T8BarNYcw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+effects+of+aging+and+physical+activity+on+Doppler+measures+of+diastolic+function&rft.jtitle=The+American+journal+of+cardiology&rft.au=Prasad%2C+Anand&rft.au=Popovic%2C+Zoran+B&rft.au=Arbab-Zadeh%2C+Armin&rft.au=Fu%2C+Qi&rft.date=2007-06-15&rft.issn=0002-9149&rft.volume=99&rft.issue=12&rft.spage=1629&rft_id=info:doi/10.1016%2Fj.amjcard.2007.01.050&rft_id=info%3Apmid%2F17560865&rft.externalDocID=17560865 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F00029149%2FS0002914907X11172%2Fcov150h.gif |