Extracellular matrix production by adipose-derived stem cells: Implications for heart valve tissue engineering - Colazzo, Francesca; Sarathchandra, Padmini; Smolenski, Ryszard T.; Chester, Adrian H.; Tseng, Yuan-Tsan; Czernuszka, Jan T.; Yacoub, Magdi H.; Taylor, Patricia M. (Biomaterials, 2011)
Keywords: adipose tissue; Adipose Tissue - cytology; Adipose-derived stem cells; Adult; Advanced Basic Science; Amino Acids; Amino Acids - metabolism; aorta; bone marrow; cattle; Cell Shape; Cell Shape - drug effects; chemistry; Collagen; Collagen - metabolism; Collagens; Cross-Linking Reagents; Cross-Linking Reagents - pharmacology; Crosslinking; Crosslinks; cytology; Dentistry; Desmosine; Desmosine - metabolism; drug effects; Elastin; Elastin - metabolism; enzymes; Extracellular matrix; Extracellular Matrix - drug effects; Extracellular Matrix - metabolism; fluorescent antibody technique; gene expression regulation; Gene Expression Regulation - drug effects; genes; Heart valve; Heart Valve Prosthesis; Heart valves; Human; Humans; liquid chromatography; mass spectrometry; Mesenchymal Stem Cells; Mesenchymal Stromal Cells - cytology; Mesenchymal Stromal Cells - drug effects; Mesenchymal Stromal Cells - metabolism; Mesenchymal Stromal Cells - ultrastructure; metabolism; methods; Middle Aged; pharmacology; Phenotype; proline; Proline - metabolism; quantitative polymerase chain reaction; radiolabeling; Scaffolds; sowing; Stem cells; Stem Cells - cytology; Stem Cells - drug effects; Stem Cells - metabolism; Stem Cells - ultrastructure; Stress, Mechanical; Tissue engineering; Tissue Engineering - methods; tissue scaffolds; Tissue Scaffolds - chemistry; transmission electron microscopy; tritium; ultrastructure; Valves; Crosslinks; Extracellular matrix; Adipose-derived stem cells; Heart valve; Collagen; Elastin