Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study - Reiman, Eric M; Quiroz, Yakeel T; Fleisher, Adam S; Chen, Kewei; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Fagan, Anne M; Shah, Aarti R; Alvarez, Sergio; Arbelaez, Andrés; Giraldo, Margarita; Acosta-Baena, Natalia; et al. (Lancet neurology, 2012)
Keywords: Adolescent; Adult; Alzheimer Disease - diagnosis; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - blood; Amyloid beta-Peptides - cerebrospinal fluid; Biomarkers; Biomarkers - blood; Biomarkers - cerebrospinal fluid; Brain - pathology; Case-Control Studies; Cross-Sectional Studies; Female; Genes, Dominant; Genetic Predisposition to Disease - genetics; Humans; Magnetic Resonance Imaging - methods; Male; Medical imaging; Mutation; Mutation - genetics; Neuroimaging; Neurology; Peptide Fragments - blood; Peptide Fragments - cerebrospinal fluid; Presenilin-1 - blood; Presenilin-1 - cerebrospinal fluid; Presenilin-1 - genetics; Risk Factors; Young Adult; Young adults