Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program - Frye, Maike; Taddei, Andrea; Dierkes, Cathrin; Martinez-Corral, Ines; Fielden, Matthew; Ortsäter, Henrik; Kazenwadel, Jan; Calado, Dinis P.; Ostergaard, Pia; Salminen, Marjo; He, Liqun; Harvey, Natasha L.; et al. (Nature communications, 2018)
Keywords: 13/1; 13/31; 13/51; 13/89; 14; 14/19; 14/3; 38; 38/1; 38/15; 38/39; 38/61; 45/88; 45/90; 631/136/2060/290; 631/80/79/2066; 631/80/84/750; 64/110; Animal models; Animals; Atomic force microscopy; Blood vessels; Cell adhesion & migration; Cell culture; Cell migration; Cell Movement - genetics; Embryos; Endothelial cells; Endothelial Cells - physiology; Extracellular matrix; Female; GATA2 Transcription Factor - genetics; GATA2 Transcription Factor - metabolism; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Gene regulation; Humanities and Social Sciences; Humans; In vivo methods and tests; Lymphangiogenesis - genetics; Lymphatic system; Lymphatic Vessels - cytology; Lymphatic Vessels - physiology; Male; Mice; Mice, Transgenic; Morphogenesis; multidisciplinary; Primary Cell Culture; RNA, Small Interfering - metabolism; Rodents; Science; Science (multidisciplinary); Stiffening; Stiffness; Substrates; Transcription; Vascular endothelial growth factor; Vascular Endothelial Growth Factor C - metabolism; Vascular Endothelial Growth Factor Receptor-3 - genetics; Vascular Endothelial Growth Factor Receptor-3 - metabolism; Vascular endothelial growth factor receptors