Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients - Befroy, Douglas E.; Petersen, Kitt Falk; Dufour, Sylvie; Mason, Graeme F.; de Graaf, Robin A.; Rothman, Douglas L.; Shulman, Gerald I. (Diabetes (New York, N.Y.), 2007)
Keywords: Adult; Biological and medical sciences; Body Mass Index; Carbon Isotopes; Chemical properties; Citric Acid Cycle; Diabetes; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Fatty acids; Female; Glucose Tolerance Test; Health aspects; Humans; Hypotheses; Insulin resistance; Insulin Resistance - physiology; Kinases; Kinetics; Life Style; Lipids; Magnetic Resonance Spectroscopy; Male; Medical sciences; Metabolism; Metabolites; Mitochondria, Muscle - metabolism; Models, Biological; Musculoskeletal system; Nuclear Family; Oxidation; Oxidation-Reduction; Oxidation-reduction reaction; Oxidation-reduction reactions; Pathogenesis; Phosphorylation; Physiological aspects; Spectrum analysis; Type 2 diabetes; United States; Endocrinopathy; Type 2 diabetes; Human; Pancreatic hormone; Mitochondria; Metabolic diseases; Muscle; Oxidation; Insulin