Proteomic analysis of fatty liver induced by starvation of medaka fish larvae

• Published in: Cell Structure and Function Vol. 48; no. 2; pp. 123 - 133
• Main Authors: Ikeda, Tomoyo, Ishikawa, Tokiro, Ninagawa, Satoshi, Okada, Tetsuya, Ono, Masaya, Mori, Kazutoshi
• Format: Journal Article
• Language: English
• Published: Japan Japan Society for Cell Biology 01.01.2023; Japan Science and Technology Agency
• Subjects: Acids; amino acid catabolism; Amino Acids; Animals; Autophagy; Cholesterol; Chromatography; Cirrhosis; Endoplasmic reticulum; Enzymes; export; Fatty acids; Fatty Acids - metabolism; Fatty liver; Fatty Liver - veterinary; Full; Genes; Glucose; Glycolysis; Larva - metabolism; Larvae; Liver; Mass spectrometry; Oryzias - metabolism; Peptides; Proteins; Proteomics; Scientific imaging; triacylglycerol; Tricarboxylic acid cycle; Triglycerides - metabolism; β-oxidation; β-oxidation; cholesterol; triacylglycerol; amino acid catabolism; export

When medaka fish (Oryzias latipes) larvae are grown in the absence of exogenous nutrition, the liver becomes dark and positive to Oil Red O staining from 7 days post-hatch (dph). We determined the mechanism of this starvation-induced development of fatty liver by proteomic analysis using livers obta...