Epigenetics in Human Obesity and Type 2 Diabetes

• Published in: Cell metabolism Vol. 29; no. 5; pp. 1028 - 1044
• Main Authors: Ling, Charlotte, Rönn, Tina
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 07.05.2019; Cell Press
• Subjects: aging; Basic Medicine; diet; DNA methylation; epigenetics; exercise; Health Sciences; histone modifications; Hälsovetenskap; Medical and Health Sciences; Medical Genetics; Medical Genetics and Genomics (including Gene Therapy); Medicin och hälsovetenskap; Medicinsk genetik; Medicinsk genetik och genomik (Här ingår: Genterapi); Medicinska och farmaceutiska grundvetenskaper; obesity; physical activity; prediction; type 2 diabetes; type 2 diabetes; DNA methylation; prediction; exercise; histone modifications; aging; diet; epigenetics; obesity; physical activity

Epigenetic mechanisms control gene activity and the development of an organism. The epigenome includes DNA methylation, histone modifications, and RNA-mediated processes, and disruption of this balance may cause several pathologies and contribute to obesity and type 2 diabetes (T2D). This Review sum...