Induced-fit expansion and contraction of a self-assembled nanocube finely responding to neutral and anionic guests

• Published in: Nature communications Vol. 9; no. 1; pp. 4530 - 6
• Main Authors: 中村 貴志, Zhan Yi-Yang, Kojima Tatsuo, Takahashi Toshihiro, Takahashi Satoshi, Haketa Yohei, Shoji Yoshiaki, Maeda Hiromitsu, Fukushima Takanori, Hiraoka Shuichi
• Format: Journal Article
• Language: English
• Published: London Nature 31.10.2018; Nature Publishing Group UK; Nature Publishing Group; Nature Portfolio
• Subjects: 140/131; 639/638/541/965; 639/638/541/966; Binding sites; Chemistry; Conformation; Contraction; Humanities and Social Sciences; Hydrophobicity; multidisciplinary; Receptors; Science; Science (multidisciplinary); Self-assembly

Induced-fit or conformational selection is of profound significance in biological regulation. Biological receptors alter their conformation to respond to the shape and electrostatic surfaces of guest molecules. Here we report a water-soluble artificial molecular host that can sensitively respond to...