What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health?
Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtur...
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| Published in | Environmental health perspectives Vol. 124; no. 1; pp. A6 - A9 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
National Institute of Environmental Health Sciences
01.01.2016
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evolve in the field of environmental epidemiology, it is imperative that we understand the methodologic challenges of this research and the types of questions we can address using epidemiological data. In this article, we summarize some of the unique challenges in exposure assessment, statistical methods, and methodology that epidemiologists face in addressing chemical mixtures. We propose three broad questions that epidemiological studies can address: a) What are the potential health impacts of individual chemical agents? b) What is the interaction among agents? And c) what are the health effects of cumulative exposure to multiple agents? As the field of mixtures research grows, we can use these three questions as a basis for defining our research questions and for developing methods that will help us better understand the effect of chemical exposures on human disease and well-being. |
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| AbstractList | Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evolve in the field of environmental epidemiology, it is imperative that we understand the methodologic challenges of this research and the types of questions we can address using epidemiological data. In this article, we summarize some of the unique challenges in exposure assessment, statistical methods, and methodology that epidemiologists face in addressing chemical mixtures. We propose three broad questions that epidemiological studies can address: a) What are the potential health impacts of individual chemical agents? b) What is the interaction among agents? And c) what are the health effects of cumulative exposure to multiple agents? As the field of mixtures research grows, we can use these three questions as a basis for defining our research questions and for developing methods that will help us better understand the effect of chemical exposures on human disease and well-being. Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evolve in the field of environmental epidemiology, it is imperative that we understand the methodologic challenges of this research and the types of questions we can address using epidemiological data. In this article, we summarize some of the unique challenges in exposure assessment, statistical methods, and methodology that epidemiologists face in addressing chemical mixtures. We propose three broad questions that epidemiological studies can address: a) What are the potential health impacts of individual chemical agents? b) What is the interaction among agents? And c) what are the health effects of cumulative exposure to multiple agents? As the field of mixtures research grows, we can use these three questions as a basis for defining our research questions and for developing methods that will help us better understand the effect of chemical exposures on human disease and well-being.Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evolve in the field of environmental epidemiology, it is imperative that we understand the methodologic challenges of this research and the types of questions we can address using epidemiological data. In this article, we summarize some of the unique challenges in exposure assessment, statistical methods, and methodology that epidemiologists face in addressing chemical mixtures. We propose three broad questions that epidemiological studies can address: a) What are the potential health impacts of individual chemical agents? b) What is the interaction among agents? And c) what are the health effects of cumulative exposure to multiple agents? As the field of mixtures research grows, we can use these three questions as a basis for defining our research questions and for developing methods that will help us better understand the effect of chemical exposures on human disease and well-being. Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evolve in the field of environmental epidemiology, it is imperative that we understand the methodologic challenges of this research and the types of questions we can address using epidemiological data. In this article, we summarize some of the unique challenges in exposure assessment, statistical methods, and methodology that epidemiologists face in addressing chemical mixtures. We propose three broad questions that epidemiological studies can address: a ) What are the potential health impacts of individual chemical agents? b ) What is the interaction among agents? And c ) what are the health effects of cumulative exposure to multiple agents? As the field of mixtures research grows, we can use these three questions as a basis for defining our research questions and for developing methods that will help us better understand the effect of chemical exposures on human disease and well-being. |
| Audience | Academic |
| Author | Webster, Thomas F. Hauser, Russ Gennings, Chris Braun, Joseph M. |
| Author_xml | – sequence: 1 givenname: Joseph M. surname: Braun fullname: Braun, Joseph M. organization: Department of Epidemiology, Brown University, Providence, Rhode Island, USA – sequence: 2 givenname: Chris surname: Gennings fullname: Gennings, Chris organization: Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 3 givenname: Russ surname: Hauser fullname: Hauser, Russ organization: Departments of Environmental Health and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA – sequence: 4 givenname: Thomas F. surname: Webster fullname: Webster, Thomas F. organization: Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26720830$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1093/toxsci/kfv196 10.1016/j.annepidem.2011.11.004 10.1016/j.jclinepi.2014.03.012 10.1093/ije/dys003 10.1289/ehp.1408933 10.1289/ehp.1002727 10.1542/peds.2009-3556 10.1289/ehp.1205889 10.7326/0003-4819-105-3-445 10.1097/00001648-199001000-00010 10.1016/j.envres.2009.01.003 10.1080/00039890009603406 10.1016/j.envint.2012.10.004 10.1158/1055-9965.EPI-05-0456 10.1093/biostatistics/kxu058 10.1289/ehp.1003300 10.1016/0890-6238(93)90242-Y 10.1111/j.1742-7843.2007.00185.x 10.1289/ehp.1408750 10.1289/ehp.1509752 10.1289/ehp.1307261 10.1289/ehp.1408630 10.1093/aje/kwt314 10.1289/ehp.1206182 10.1186/1476-069X-12-85 10.1097/00001648-200105000-00005 10.1289/ehp.98106s41051 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2016 National Institute of Environmental Health Sciences Copyright National Institute of Environmental Health Sciences Jan 2016 |
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| References | e_1_3_3_18_1 e_1_3_3_17_1 e_1_3_3_19_1 e_1_3_3_14_1 e_1_3_3_13_1 e_1_3_3_16_1 e_1_3_3_15_1 e_1_3_3_10_1 e_1_3_3_12_1 e_1_3_3_11_1 e_1_3_3_7_1 e_1_3_3_6_1 e_1_3_3_9_1 e_1_3_3_8_1 e_1_3_3_29_1 e_1_3_3_28_1 e_1_3_3_25_1 e_1_3_3_24_1 e_1_3_3_27_1 e_1_3_3_26_1 e_1_3_3_3_1 e_1_3_3_21_1 e_1_3_3_2_1 e_1_3_3_20_1 e_1_3_3_5_1 e_1_3_3_23_1 e_1_3_3_4_1 e_1_3_3_22_1 22226033 - Ann Epidemiol. 2012 Feb;22(2):126-41 10908103 - Arch Environ Health. 2000 May-Jun;55(3):195-200 24401560 - Am J Epidemiol. 2014 Mar 1;179(5):545-7 2081237 - Epidemiology. 1990 Jan;1(1):43-6 22421054 - Int J Epidemiol. 2012 Jun;41(3):828-43 23262415 - Environ Int. 2013 Jan;51:174-81 9703492 - Environ Health Perspect. 1998 Aug;106 Suppl 4:1051-8 23409283 - Environ Health Perspect. 2013 Jan;121(1):A6-8 21187307 - Pediatrics. 2011 Jan;127(1):e59-68 8499671 - Reprod Toxicol. 1993;7(2):95-100 25748701 - Environ Health Perspect. 2015 Oct;123(10):965-70 26350170 - Toxicol Sci. 2015 Dec;148(2):488-502 3740684 - Ann Intern Med. 1986 Sep;105(3):445-7 11337599 - Epidemiology. 2001 May;12(3):291-4 19251256 - Environ Res. 2009 May;109(4):368-78 16103423 - Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1847-50 21885384 - Environ Health Perspect. 2012 Jan;120(1):126-31 26115335 - Environ Health Perspect. 2016 Mar;124(3):365-72 23014866 - Environ Health Perspect. 2013 Jan;121(1):1-6 25532525 - Biostatistics. 2015 Jul;16(3):493-508 18226062 - Basic Clin Pharmacol Toxicol. 2008 Feb;102(2):100-8 24093917 - Environ Health. 2013;12(1):85 24831050 - J Clin Epidemiol. 2014 Aug;67(8):850-7 24622245 - Environ Health Perspect. 2014 May;122(5):513-20 26069025 - Environ Health Perspect. 2016 Apr;124(4):514-20 21233055 - Environ Health Perspect. 2011 Jun;119(6):878-85 26372668 - Environ Health Perspect. 2016 Apr;124(4):498-506 |
| References_xml | – ident: e_1_3_3_14_1 doi: 10.1093/toxsci/kfv196 – ident: e_1_3_3_3_1 doi: 10.1016/j.annepidem.2011.11.004 – ident: e_1_3_3_12_1 doi: 10.1016/j.jclinepi.2014.03.012 – ident: e_1_3_3_19_1 doi: 10.1093/ije/dys003 – ident: e_1_3_3_8_1 – ident: e_1_3_3_15_1 doi: 10.1289/ehp.1408933 – ident: e_1_3_3_29_1 doi: 10.1289/ehp.1002727 – ident: e_1_3_3_6_1 doi: 10.1542/peds.2009-3556 – ident: e_1_3_3_13_1 doi: 10.1289/ehp.1205889 – ident: e_1_3_3_21_1 doi: 10.7326/0003-4819-105-3-445 – ident: e_1_3_3_22_1 doi: 10.1097/00001648-199001000-00010 – ident: e_1_3_3_2_1 doi: 10.1016/j.envres.2009.01.003 – ident: e_1_3_3_16_1 doi: 10.1080/00039890009603406 – ident: e_1_3_3_27_1 doi: 10.1016/j.envint.2012.10.004 – ident: e_1_3_3_28_1 doi: 10.1158/1055-9965.EPI-05-0456 – ident: e_1_3_3_4_1 doi: 10.1093/biostatistics/kxu058 – ident: e_1_3_3_9_1 doi: 10.1289/ehp.1003300 – ident: e_1_3_3_24_1 doi: 10.1016/0890-6238(93)90242-Y – ident: e_1_3_3_18_1 doi: 10.1111/j.1742-7843.2007.00185.x – ident: e_1_3_3_17_1 doi: 10.1289/ehp.1408750 – ident: e_1_3_3_10_1 doi: 10.1289/ehp.1509752 – ident: e_1_3_3_5_1 doi: 10.1289/ehp.1307261 – ident: e_1_3_3_11_1 doi: 10.1289/ehp.1408630 – ident: e_1_3_3_25_1 doi: 10.1093/aje/kwt314 – ident: e_1_3_3_7_1 doi: 10.1289/ehp.1206182 – ident: e_1_3_3_26_1 doi: 10.1186/1476-069X-12-85 – ident: e_1_3_3_20_1 doi: 10.1097/00001648-200105000-00005 – ident: e_1_3_3_23_1 doi: 10.1289/ehp.98106s41051 – reference: 26350170 - Toxicol Sci. 2015 Dec;148(2):488-502 – reference: 21233055 - Environ Health Perspect. 2011 Jun;119(6):878-85 – reference: 25532525 - Biostatistics. 2015 Jul;16(3):493-508 – reference: 23409283 - Environ Health Perspect. 2013 Jan;121(1):A6-8 – reference: 26115335 - Environ Health Perspect. 2016 Mar;124(3):365-72 – reference: 24401560 - Am J Epidemiol. 2014 Mar 1;179(5):545-7 – reference: 23262415 - Environ Int. 2013 Jan;51:174-81 – reference: 26069025 - Environ Health Perspect. 2016 Apr;124(4):514-20 – reference: 9703492 - Environ Health Perspect. 1998 Aug;106 Suppl 4:1051-8 – reference: 10908103 - Arch Environ Health. 2000 May-Jun;55(3):195-200 – reference: 8499671 - Reprod Toxicol. 1993;7(2):95-100 – reference: 3740684 - Ann Intern Med. 1986 Sep;105(3):445-7 – reference: 19251256 - Environ Res. 2009 May;109(4):368-78 – reference: 21187307 - Pediatrics. 2011 Jan;127(1):e59-68 – reference: 25748701 - Environ Health Perspect. 2015 Oct;123(10):965-70 – reference: 2081237 - Epidemiology. 1990 Jan;1(1):43-6 – reference: 22226033 - Ann Epidemiol. 2012 Feb;22(2):126-41 – reference: 11337599 - Epidemiology. 2001 May;12(3):291-4 – reference: 24831050 - J Clin Epidemiol. 2014 Aug;67(8):850-7 – reference: 26372668 - Environ Health Perspect. 2016 Apr;124(4):498-506 – reference: 18226062 - Basic Clin Pharmacol Toxicol. 2008 Feb;102(2):100-8 – reference: 21885384 - Environ Health Perspect. 2012 Jan;120(1):126-31 – reference: 24622245 - Environ Health Perspect. 2014 May;122(5):513-20 – reference: 24093917 - Environ Health. 2013;12(1):85 – reference: 22421054 - Int J Epidemiol. 2012 Jun;41(3):828-43 – reference: 23014866 - Environ Health Perspect. 2013 Jan;121(1):1-6 – reference: 16103423 - Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1847-50 |
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| Title | What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health? |
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