Hippocampal–prefrontal input supports spatial encoding in working memory

Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the prefrontal cortex and hippocampus are known to contribute jointly to successful spatial working memory, the anatomical pathway and temporal wi...

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Published inNature (London) Vol. 522; no. 7556; pp. 309 - 314
Main Authors Spellman, Timothy, Rigotti, Mattia, Ahmari, Susanne E., Fusi, Stefano, Gogos, Joseph A., Gordon, Joshua A.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 18.06.2015
Nature Publishing Group
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Abstract Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the prefrontal cortex and hippocampus are known to contribute jointly to successful spatial working memory, the anatomical pathway and temporal window for the interaction of these structures critical to spatial working memory has not yet been established. Here we find that direct hippocampal–prefrontal afferents are critical for encoding, but not for maintenance or retrieval, of spatial cues in mice. These cues are represented by the activity of individual prefrontal units in a manner that is dependent on hippocampal input only during the cue-encoding phase of a spatial working memory task. Successful encoding of these cues appears to be mediated by gamma-frequency synchrony between the two structures. These findings indicate a critical role for the direct hippocampal–prefrontal afferent pathway in the continuous updating of task-related spatial information during spatial working memory. Spatial working memory is known to involve the prefrontal cortex and the hippocampus, but the specificities of the connection have been unclear; now, a direct path between these two areas is defined that is necessary for the encoding of spatial cues in mice, but is not required for the maintenance or retrieval of these cues. The nature of spatial memory Spatial working memory is maintained through a coordination of activity between prefrontal brain areas and the hippocampus, but it has been unclear what the precise anatomical connections between these areas are and on what time scales they operate. Here, Joshua Gordon and colleagues define a direct path between prefrontal cortex and hippocampus that is necessary for proper encoding of spatial cues, but is not required for maintenance and retrieval of these cues. Hippocampal information flows to neural units in the prefrontal cortex during the encoding phases of spatial working memory tasks, with successful encoding requiring synchrony between the two brain structures in the gamma-frequency band of network activity. These findings demonstrate the critical importance of hippocampal–prefrontal direct input in the continuous updating of spatial information.
AbstractList Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the prefrontal cortex and hippocampus are known to contribute jointly to successful spatial working memory, the anatomical pathway and temporal window for the interaction of these structures critical to spatial working memory has not yet been established. Here we find that direct hippocampal-prefrontal afferents are critical for encoding, but not for maintenance or retrieval, of spatial cues in mice. These cues are represented by the activity of individual prefrontal units in a manner that is dependent on hippocampal input only during the cue-encoding phase of a spatial working memory task. Successful encoding of these cues appears to be mediated by gamma-frequency synchrony between the two structures. These findings indicate a critical role for the direct hippocampal-prefrontal afferent pathway in the continuous updating of task-related spatial information during spatial working memory.
Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the prefrontal cortex and hippocampus are known to contribute jointly to successful spatial working memory, the anatomical pathway and temporal window for the interaction of these structures critical to spatial working memory has not yet been established. Here we find that direct hippocampal–prefrontal afferents are critical for encoding, but not for maintenance or retrieval, of spatial cues in mice. These cues are represented by the activity of individual prefrontal units in a manner that is dependent on hippocampal input only during the cue-encoding phase of a spatial working memory task. Successful encoding of these cues appears to be mediated by gamma-frequency synchrony between the two structures. These findings indicate a critical role for the direct hippocampal–prefrontal afferent pathway in the continuous updating of task-related spatial information during spatial working memory. Spatial working memory is known to involve the prefrontal cortex and the hippocampus, but the specificities of the connection have been unclear; now, a direct path between these two areas is defined that is necessary for the encoding of spatial cues in mice, but is not required for the maintenance or retrieval of these cues. The nature of spatial memory Spatial working memory is maintained through a coordination of activity between prefrontal brain areas and the hippocampus, but it has been unclear what the precise anatomical connections between these areas are and on what time scales they operate. Here, Joshua Gordon and colleagues define a direct path between prefrontal cortex and hippocampus that is necessary for proper encoding of spatial cues, but is not required for maintenance and retrieval of these cues. Hippocampal information flows to neural units in the prefrontal cortex during the encoding phases of spatial working memory tasks, with successful encoding requiring synchrony between the two brain structures in the gamma-frequency band of network activity. These findings demonstrate the critical importance of hippocampal–prefrontal direct input in the continuous updating of spatial information.
Spatial working memory, the caching of behaviorally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. While the prefrontal cortex and hippocampus are known to jointly contribute to successful spatial working memory, the anatomical pathway and temporal window for interaction of these structures critical to spatial working memory has not yet been established. Here, we find that direct hippocampal-prefrontal afferents are critical for encoding, but not for maintenance or retrieval, of spatial cues. These cues are represented by the activity of individual prefrontal units in a manner that is dependent on hippocampal input only during the cue-encoding phase of a spatial working memory task. Successful encoding of these cues appears to be mediated by gamma-frequency synchrony between the two structures. These findings indicate a critical role for the direct hippocampal-prefrontal afferent pathway in the continuous updating of task-related spatial information during spatial working memory.
Audience Academic
Author Fusi, Stefano
Gordon, Joshua A.
Spellman, Timothy
Ahmari, Susanne E.
Rigotti, Mattia
Gogos, Joseph A.
AuthorAffiliation 7 Center for Neuroscience, Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA
9 Division of Integrative Neuroscience, New York State Psychiatric Institute, New York, NY 10032 USA
1 Department of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032 USA
2 Department of Psychiatry, Columbia University
8 Kavli Institute for Brain Sciences, Columbia University
6 Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
5 Italian Academy for Advanced Studies in America, Columbia University
3 Department of Neuroscience, Columbia University
4 Physical Sciences Department, T. J. Watson Research Center, IBM 1101 Kitchawan Rd, Yorktown Heights, NY 10598, USA
AuthorAffiliation_xml – name: 3 Department of Neuroscience, Columbia University
– name: 8 Kavli Institute for Brain Sciences, Columbia University
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– name: 5 Italian Academy for Advanced Studies in America, Columbia University
– name: 6 Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
– name: 9 Division of Integrative Neuroscience, New York State Psychiatric Institute, New York, NY 10032 USA
– name: 4 Physical Sciences Department, T. J. Watson Research Center, IBM 1101 Kitchawan Rd, Yorktown Heights, NY 10598, USA
– name: 7 Center for Neuroscience, Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA
– name: 2 Department of Psychiatry, Columbia University
Author_xml – sequence: 1
  givenname: Timothy
  surname: Spellman
  fullname: Spellman, Timothy
  organization: Department of Physiology and Cellular Biophysics, Columbia University
– sequence: 2
  givenname: Mattia
  surname: Rigotti
  fullname: Rigotti, Mattia
  organization: Department of Neuroscience, Columbia University, IBM T. J. Watson Research Center, Italian Academy for Advanced Studies in America, Columbia University
– sequence: 3
  givenname: Susanne E.
  surname: Ahmari
  fullname: Ahmari, Susanne E.
  organization: Department of Psychiatry, Translational Neuroscience Program, University of Pittsburgh, Center for Neuroscience and Center for the Neural Basis of Cognition, University of Pittsburgh
– sequence: 4
  givenname: Stefano
  surname: Fusi
  fullname: Fusi, Stefano
  organization: Department of Neuroscience, Columbia University, Kavli Institute for Brain Sciences, Columbia University
– sequence: 5
  givenname: Joseph A.
  surname: Gogos
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  surname: Gordon
  fullname: Gordon, Joshua A.
  email: jg343@columbia.edu
  organization: Department of Psychiatry, Columbia University, Division of Integrative Neuroscience, New York State Psychiatric Institute
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26053122$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1162/NECO_a_00152
10.1152/jn.01192.2011
10.1016/j.cell.2010.02.037
10.1002/cne.903130404
10.1016/j.cell.2014.04.009
10.1017/CBO9781139174909
10.1038/nature08652
10.1162/089976699300016827
10.1037/0096-3445.133.3.355
10.1093/cercor/8.5.437
10.1016/j.neuron.2005.02.028
10.1038/nature13186
10.1016/j.neuroimage.2010.01.073
10.1016/j.neuron.2009.11.031
10.1038/nn.3224
10.1523/JNEUROSCI.23-04-01517.2003
10.1007/s00429-007-0150-4
10.1016/0896-6273(95)90304-6
10.1016/j.neuron.2012.07.015
10.1016/S0896-6273(03)00597-X
10.1152/jn.1989.61.2.331
10.1016/j.bbr.2006.03.030
10.1038/nature08010
10.1126/science.1157086
10.1126/science.252.5009.1177
10.1038/nrn1201
10.1523/JNEUROSCI.2378-13.2013
10.1016/j.bbr.2008.11.045
10.1111/j.1460-9568.2008.06284.x
10.1007/BF03033814
10.1016/j.bbr.2006.09.002
10.1016/j.neuron.2012.06.014
10.1101/lm.40301
10.1371/journal.pbio.0030402
10.1038/nature08855
10.3758/CABN.4.4.528
10.1016/0166-4328(93)90051-Q
10.1016/S0166-4328(05)80169-X
10.1523/JNEUROSCI.4681-09.2010
10.1523/JNEUROSCI.5458-12.2013
10.1209/0295-5075/10/7/014
10.1088/0305-4470/20/11/013
10.1152/jn.90248.2008
10.1038/nature12160
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References JungMWQinYMcNaughtonBABarnesCLFiring characteristics of deep layer neurons in prefrontal cortex in rats performing spatial working memory tasksCereb. Cortex199884374501:STN:280:DyaK1czoslGnsA%3D%3D972208710.1093/cercor/8.5.437
FanselowMADongHWAre the dorsal and ventral hippocampus functionally distinct structures?Neuron2010657191:CAS:528:DC%2BC3cXlt1Kms7k%3D20152109282272710.1016/j.neuron.2009.11.031
HooverWBVertesRPAnatomical analysis of afferent projections to the medial prefrontal cortex in the ratBrain Struct. Funct.20072121491791771769010.1007/s00429-007-0150-4
de ZubicarayGIMcMahonKWilsonSJMuthiahSBrain activity during the encoding, retention, and retrieval of stimulus representationsLearn. Mem.200182432511:STN:280:DC%2BD3Mrjs1Klsg%3D%3D1158407031138510.1101/lm.40301
RogersDCPhotothrombic lesions of the frontal cortex impair the performance of the delayed non-matching to position task by ratsBehav. Brain Res.1992492312351992lfa..book.....R1:STN:280:DyaK3s%2FgtVGrtw%3D%3D138881710.1016/S0166-4328(05)80169-X
GradinaruVMolecular and cellular approaches for diversifying and extending optogeneticsCell20101411541651:CAS:528:DC%2BC3cXlsVSgtbY%3D20303157416053210.1016/j.cell.2010.02.037
ShawCAggletonJThe effects of fornix and medial prefrontal lesions on delayed non-matching-to-sample by ratsBehav. Brain Res.199354911021:STN:280:DyaK3s3nslOitg%3D%3D850401510.1016/0166-4328(93)90051-Q
MeyersEMFreedmanDJKreimanGMillerEKPoggioTDynamic population coding of category information in inferior temporal and prefrontal cortexJ. Neurophysiol.20081001407141918562555254446610.1152/jn.90248.2008
BurtonBGHokVSaveEPoucetBLesion of the ventral and intermediate hippocampus abolishes anticipatory activity in the medial prefrontal cortex of the ratBehav. Brain Res.20091992222341910322710.1016/j.bbr.2008.11.045
SigurdssonTStarkKLKarayiorgouMGogosJAGordonJAImpaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophreniaNature20104647637672010Natur.464..763S1:CAS:528:DC%2BC3cXktVygtrY%3D20360742286458410.1038/nature08855
OhSWA mesoscale connectome of the mouse brainNature20145082072142014Natur.508..207O1:CAS:528:DC%2BC2cXmtlWjs70%3D24695228510206410.1038/nature13186
HorstNKLaubachMWorking with memory: evidence for a role for the medial prefrontal cortex in performance monitoring during spatial delayed alternationJ. Neurophysiol.20121083276328823019007354488310.1152/jn.01192.2011
RigottiMThe importance of mixed selectivity in complex cognitive tasksNature20134975855902013Natur.497..585R1:CAS:528:DC%2BC3sXotFSltbc%3D23685452441234710.1038/nature12160
HymanJMZilliEAPaleyAMHasselmoMEWorking memory performance correlates with prefrontal-hippocampal theta interactions but not with prefrontal neuron firing ratesFront. Integr Neurosci.201042204317262861479
MiyakeAShahPModels of Working Memory: Mechanisms of Active Maintenance and Executive Control199910.1017/CBO9781139174909
RoyerSSirotaAPatelJBuzsákiGDistinct representations and theta dynamics in dorsal and ventral hippocampusJ. Neurosci.201030177717871:CAS:528:DC%2BC3cXitV2jurk%3D20130187282515910.1523/JNEUROSCI.4681-09.2010
FunahashiSBruceCGoldman-RakicPMnemonic coding of visual space in the monkey’s dorsolateral prefrontal cortexJ. Neurophysiol.1989613313491:STN:280:DyaL1M7ktV2rtQ%3D%3D291835810.1152/jn.1989.61.2.331
LeeIKesnerRPTime-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memoryJ. Neurosci.200323151715231:CAS:528:DC%2BD3sXit1anurs%3D12598640674224810.1523/JNEUROSCI.23-04-01517.2003
ChowBYHigh-performance genetically targetable optical neural silencing by light-driven proton pumpsNature2010463981022010Natur.463...98C1:CAS:528:DC%2BC3cXhvFCqtg%3D%3D20054397293949210.1038/nature08652
BaddeleyAWorking memory: looking back and looking forwardNature Rev. Neurosci.200348298391:CAS:528:DC%2BD3sXnslSitr8%3D10.1038/nrn1201
VinckMvan WingerdenMWomelsdorfTFriesPPennartzCThe pairwise phase consistency: a bias-free measure of rhythmic neuronal synchronizationNeuroimage2010511121222011407610.1016/j.neuroimage.2010.01.073
LubenovEVSiapasAGHippocampal theta oscillations are travelling wavesNature20094595345392009Natur.459..534L1:CAS:528:DC%2BD1MXmtVOru7w%3D1948911710.1038/nature08010
RuedigerSSpirigDDonatoFCaroniPGoal-oriented searching mediated by ventral hippocampus early in trial-and-error learningNature Neurosci.201215156315711:CAS:528:DC%2BC38XhtlyltLjE2300106110.1038/nn.3224
CurtisCED’EspositoMThe effects of prefrontal lesions on working memory performance and theoryCogn. Affect. Behav. Neurosci.200445285391584989510.3758/CABN.4.4.528
IzakiYTakitaMAkemaTSpecific role of the posterior dorsal hippocampus-prefrontal cortex in short-term working memoryEur. J. Neurosci.200827302930341854087910.1111/j.1460-9568.2008.06284.x
DietterichTGGhulumBError-correcting output codes: a general method for improving multiclass inductive learning programsProc. AAAI199191572577
AndradeJWorking Memory in Perspective2001
AnlaufJKBiehlMThe AdaTron: an adaptive perceptron algorithmEurophys. Lett.1989106876921989EL.....10..687A10.1209/0295-5075/10/7/014
SeamansJKLapishCCDurstewitzDComparing the prefrontal cortex of rats and primates: insights from electrophysiologyNeurotox. Res.2008142492621907343010.1007/BF03033814
BaddeleyAHitchGBowerGARecent Advances in Learning and Motivation19744790
BarakORigottiMA simple derivation of a bound on the perceptron margin using singular value decompositionNeural Comput.20112319351943283990410.1162/NECO_a_00152
RosenblattFPrinciples of Neurodynamics: Perceptrons and the Theory of Brain Mechanisms19620143.43504
BaegEHDynamics of population code for working memory in the prefrontal cortexNeuron2003401771881:CAS:528:DC%2BD3sXnvVygtro%3D1452744210.1016/S0896-6273(03)00597-X
KlauerKCZhaoZDouble dissociations in visual and spatial short-term memoryJ. Exp. Psychol. Gen.20041333553811535514410.1037/0096-3445.133.3.355
YamamotoJSuhJTakeuchiDTonegawaSSuccessful execution of working memory linked to synchronized high-frequency gamma oscillationsCell20141578458571:CAS:528:DC%2BC2cXntFCqsLs%3D2476869210.1016/j.cell.2014.04.009
SloanHLGoodMDunnettSBDouble dissociation between hippocampal and prefrontal lesions on an operant delayed matching task and a water maze reference memory taskBehav. Brain Res.20061711161261667772310.1016/j.bbr.2006.03.030
JonesMWWilsonMATheta rhythms coordinate hippocampal-prefrontal interactions in a spatial working memory taskPLoS Biol.20053e40216279838128353610.1371/journal.pbio.00304021:CAS:528:DC%2BD2MXhtlWls7nP
PatelJFujisawaSBerényiARoyerSBuzsákiGTraveling theta waves along the entire septotemporal axis of the hippocampusNeuron2012754104171:CAS:528:DC%2BC38XhtFKmt77F22884325342738710.1016/j.neuron.2012.07.015
CarrMFKarlssonMPFrankLMTransient slow gamma synchrony underlies hippocampal memory replayNeuron2012757007131:CAS:528:DC%2BC38Xht1KjurjI22920260342859910.1016/j.neuron.2012.06.014
WangGWCaiJXDisconnection of the hippocampal–prefrontal cortical circuits impairs spatial working memory performance in ratsBehav. Brain Res.20061753293362006smcp.book.....W1704534810.1016/j.bbr.2006.09.002
KomorowskiRWVentral hippocampal neurons are shaped by experience to represent behaviorally relevant contextsJ. Neurosci.201333807980871:CAS:528:DC%2BC3sXhtl2jsrfO23637197366735110.1523/JNEUROSCI.5458-12.2013
AbbottLFDayanPThe effect of correlated variability on the accuracy of a population codeNeural Comput.199911911011:STN:280:DyaK1M7js1Smug%3D%3D995072410.1162/089976699300016827
JayTMWitterMPDistribution of hippocampal CA1 and subicular afferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris-leucoagglutinineJ. Comp. Neurol.19913135745861:STN:280:DyaK387ksl2jtA%3D%3D178368210.1002/cne.903130404
EngelAKKonigPKreiterAKSingerWInterhemispheric synchronization of oscillatory neuronal responses in cat visual cortexScience1991252117711791991Sci...252.1177E1:STN:280:DyaK3M3jtleksw%3D%3D203118810.1126/science.252.5009.1177
O’NeillPKGordonJASigurdssonTTheta oscillations in the medial prefrontal cortex are modulated by spatial working memory and synchronize with the hippocampus through its ventral subregionJ. Neurosci.201333142111422423986255375676310.1523/JNEUROSCI.2378-13.20131:CAS:528:DC%2BC3sXhsVehurbL
KrauthWMezardMLearning algorithms with optimal stability in neural networksJ. Phys. A Math. Gen.198720L745L7521987JPhA...20L.745K91403910.1088/0305-4470/20/11/013
Goldman-RakicPSCellular basis of working memoryNeuron1995144774851:CAS:528:DyaK2MXkvVegt7g%3D769589410.1016/0896-6273(95)90304-6
SiapasAGLubenovEVWilsonMAPrefrontal phase locking to hippocampal theta oscillationsNeuron2005461411511:CAS:528:DC%2BD2MXjslSgsb4%3D1582070010.1016/j.neuron.2005.02.028
KjelstrupKBFinite scale of spatial representation in the hippocampusScience20083211401432008Sci...321..140K1:CAS:528:DC%2BD1cXnvFektr0%3D1859979210.1126/science.1157086
11584070 - Learn Mem. 2001 Sep-Oct;8(5):243-51
16279838 - PLoS Biol. 2005 Dec;3(12):e402
16677723 - Behav Brain Res. 2006 Jul 15;171(1):116-26
22884325 - Neuron. 2012 Aug 9;75(3):410-7
20431726 - Front Integr Neurosci. 2010 Mar 10;4:2
8504015 - Behav Brain Res. 1993 Mar 31;54(1):91-102
23637197 - J Neurosci. 2013 May 1;33(18):8079-87
9722087 - Cereb Cortex. 1998 Jul-Aug;8(5):437-50
15355144 - J Exp Psychol Gen. 2004 Sep;133(3):355-81
24695228 - Nature. 2014 Apr 10;508(7495):207-14
7695894 - Neuron. 1995 Mar;14(3):477-85
1388817 - Behav Brain Res. 1992 Aug 10;49(2):231-5
20303157 - Cell. 2010 Apr 2;141(1):154-65
23001061 - Nat Neurosci. 2012 Nov;15(11):1563-71
19489117 - Nature. 2009 May 28;459(7246):534-9
14523382 - Nat Rev Neurosci. 2003 Oct;4(10):829-39
19103227 - Behav Brain Res. 2009 May 16;199(2):222-34
18562555 - J Neurophysiol. 2008 Sep;100(3):1407-19
20114076 - Neuroimage. 2010 May 15;51(1):112-22
12598640 - J Neurosci. 2003 Feb 15;23(4):1517-23
2031188 - Science. 1991 May 24;252(5009):1177-9
17717690 - Brain Struct Funct. 2007 Sep;212(2):149-79
23019007 - J Neurophysiol. 2012 Dec;108(12):3276-88
23685452 - Nature. 2013 May 30;497(7451):585-90
23986255 - J Neurosci. 2013 Aug 28;33(35):14211-24
17045348 - Behav Brain Res. 2006 Dec 15;175(2):329-36
15849895 - Cogn Affect Behav Neurosci. 2004 Dec;4(4):528-39
18599792 - Science. 2008 Jul 4;321(5885):140-3
1783682 - J Comp Neurol. 1991 Nov 22;313(4):574-86
18540879 - Eur J Neurosci. 2008 Jun;27(11):3029-34
15820700 - Neuron. 2005 Apr 7;46(1):141-51
9950724 - Neural Comput. 1999 Jan 1;11(1):91-101
20360742 - Nature. 2010 Apr 1;464(7289):763-7
20054397 - Nature. 2010 Jan 7;463(7277):98-102
14527442 - Neuron. 2003 Sep 25;40(1):177-88
20130187 - J Neurosci. 2010 Feb 3;30(5):1777-87
24768692 - Cell. 2014 May 8;157(4):845-57
19073430 - Neurotox Res. 2008 Oct;14(2-3):249-62
20152109 - Neuron. 2010 Jan 14;65(1):7-19
22920260 - Neuron. 2012 Aug 23;75(4):700-13
2918358 - J Neurophysiol. 1989 Feb;61(2):331-49
BY Chow (BFnature14445_CR20) 2010; 463
Y Izaki (BFnature14445_CR35) 2008; 27
KC Klauer (BFnature14445_CR2) 2004; 133
I Lee (BFnature14445_CR11) 2003; 23
JK Anlauf (BFnature14445_CR46) 1989; 10
A Miyake (BFnature14445_CR4) 1999
GI de Zubicaray (BFnature14445_CR6) 2001; 8
KB Kjelstrup (BFnature14445_CR18) 2008; 321
MA Fanselow (BFnature14445_CR41) 2010; 65
S Ruediger (BFnature14445_CR40) 2012; 15
BG Burton (BFnature14445_CR16) 2009; 199
JK Seamans (BFnature14445_CR31) 2008; 14
PK O’Neill (BFnature14445_CR39) 2013; 33
TM Jay (BFnature14445_CR14) 1991; 313
M Rigotti (BFnature14445_CR22) 2013; 497
F Rosenblatt (BFnature14445_CR47) 1962
NK Horst (BFnature14445_CR28) 2012; 108
MW Jung (BFnature14445_CR17) 1998; 8
A Baddeley (BFnature14445_CR1) 1974
TG Dietterich (BFnature14445_CR49) 1991; 91
S Royer (BFnature14445_CR19) 2010; 30
W Krauth (BFnature14445_CR48) 1987; 20
SW Oh (BFnature14445_CR15) 2014; 508
AK Engel (BFnature14445_CR23) 1991; 252
EH Baeg (BFnature14445_CR27) 2003; 40
GW Wang (BFnature14445_CR12) 2006; 175
C Shaw (BFnature14445_CR33) 1993; 54
EM Meyers (BFnature14445_CR43) 2008; 100
J Andrade (BFnature14445_CR3) 2001
JM Hyman (BFnature14445_CR8) 2010; 4
LF Abbott (BFnature14445_CR44) 1999; 11
PS Goldman-Rakic (BFnature14445_CR30) 1995; 14
T Sigurdsson (BFnature14445_CR10) 2010; 464
O Barak (BFnature14445_CR45) 2011; 23
MF Carr (BFnature14445_CR24) 2012; 75
J Patel (BFnature14445_CR38) 2012; 75
J Yamamoto (BFnature14445_CR25) 2014; 157
DC Rogers (BFnature14445_CR32) 1992; 49
CE Curtis (BFnature14445_CR7) 2004; 4
AG Siapas (BFnature14445_CR36) 2005; 46
S Funahashi (BFnature14445_CR29) 1989; 61
A Baddeley (BFnature14445_CR5) 2003; 4
RW Komorowski (BFnature14445_CR42) 2013; 33
M Vinck (BFnature14445_CR26) 2010; 51
HL Sloan (BFnature14445_CR34) 2006; 171
WB Hoover (BFnature14445_CR13) 2007; 212
EV Lubenov (BFnature14445_CR37) 2009; 459
MW Jones (BFnature14445_CR9) 2005; 3
V Gradinaru (BFnature14445_CR21) 2010; 141
References_xml – volume: 23
  start-page: 1935
  year: 2011
  ident: BFnature14445_CR45
  publication-title: Neural Comput.
  doi: 10.1162/NECO_a_00152
  contributor:
    fullname: O Barak
– volume: 108
  start-page: 3276
  year: 2012
  ident: BFnature14445_CR28
  publication-title: J. Neurophysiol.
  doi: 10.1152/jn.01192.2011
  contributor:
    fullname: NK Horst
– volume: 141
  start-page: 154
  year: 2010
  ident: BFnature14445_CR21
  publication-title: Cell
  doi: 10.1016/j.cell.2010.02.037
  contributor:
    fullname: V Gradinaru
– volume: 313
  start-page: 574
  year: 1991
  ident: BFnature14445_CR14
  publication-title: J. Comp. Neurol.
  doi: 10.1002/cne.903130404
  contributor:
    fullname: TM Jay
– start-page: 47
  volume-title: Recent Advances in Learning and Motivation
  year: 1974
  ident: BFnature14445_CR1
  contributor:
    fullname: A Baddeley
– volume: 157
  start-page: 845
  year: 2014
  ident: BFnature14445_CR25
  publication-title: Cell
  doi: 10.1016/j.cell.2014.04.009
  contributor:
    fullname: J Yamamoto
– volume-title: Models of Working Memory: Mechanisms of Active Maintenance and Executive Control
  year: 1999
  ident: BFnature14445_CR4
  doi: 10.1017/CBO9781139174909
  contributor:
    fullname: A Miyake
– volume: 463
  start-page: 98
  year: 2010
  ident: BFnature14445_CR20
  publication-title: Nature
  doi: 10.1038/nature08652
  contributor:
    fullname: BY Chow
– volume: 11
  start-page: 91
  year: 1999
  ident: BFnature14445_CR44
  publication-title: Neural Comput.
  doi: 10.1162/089976699300016827
  contributor:
    fullname: LF Abbott
– volume-title: Principles of Neurodynamics: Perceptrons and the Theory of Brain Mechanisms
  year: 1962
  ident: BFnature14445_CR47
  contributor:
    fullname: F Rosenblatt
– volume: 133
  start-page: 355
  year: 2004
  ident: BFnature14445_CR2
  publication-title: J. Exp. Psychol. Gen.
  doi: 10.1037/0096-3445.133.3.355
  contributor:
    fullname: KC Klauer
– volume: 8
  start-page: 437
  year: 1998
  ident: BFnature14445_CR17
  publication-title: Cereb. Cortex
  doi: 10.1093/cercor/8.5.437
  contributor:
    fullname: MW Jung
– volume: 46
  start-page: 141
  year: 2005
  ident: BFnature14445_CR36
  publication-title: Neuron
  doi: 10.1016/j.neuron.2005.02.028
  contributor:
    fullname: AG Siapas
– volume: 508
  start-page: 207
  year: 2014
  ident: BFnature14445_CR15
  publication-title: Nature
  doi: 10.1038/nature13186
  contributor:
    fullname: SW Oh
– volume: 4
  start-page: 2
  year: 2010
  ident: BFnature14445_CR8
  publication-title: Front. Integr Neurosci.
  contributor:
    fullname: JM Hyman
– volume: 51
  start-page: 112
  year: 2010
  ident: BFnature14445_CR26
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2010.01.073
  contributor:
    fullname: M Vinck
– volume: 91
  start-page: 572
  year: 1991
  ident: BFnature14445_CR49
  publication-title: Proc. AAAI
  contributor:
    fullname: TG Dietterich
– volume: 65
  start-page: 7
  year: 2010
  ident: BFnature14445_CR41
  publication-title: Neuron
  doi: 10.1016/j.neuron.2009.11.031
  contributor:
    fullname: MA Fanselow
– volume: 15
  start-page: 1563
  year: 2012
  ident: BFnature14445_CR40
  publication-title: Nature Neurosci.
  doi: 10.1038/nn.3224
  contributor:
    fullname: S Ruediger
– volume: 23
  start-page: 1517
  year: 2003
  ident: BFnature14445_CR11
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.23-04-01517.2003
  contributor:
    fullname: I Lee
– volume: 212
  start-page: 149
  year: 2007
  ident: BFnature14445_CR13
  publication-title: Brain Struct. Funct.
  doi: 10.1007/s00429-007-0150-4
  contributor:
    fullname: WB Hoover
– volume: 14
  start-page: 477
  year: 1995
  ident: BFnature14445_CR30
  publication-title: Neuron
  doi: 10.1016/0896-6273(95)90304-6
  contributor:
    fullname: PS Goldman-Rakic
– volume: 75
  start-page: 410
  year: 2012
  ident: BFnature14445_CR38
  publication-title: Neuron
  doi: 10.1016/j.neuron.2012.07.015
  contributor:
    fullname: J Patel
– volume: 40
  start-page: 177
  year: 2003
  ident: BFnature14445_CR27
  publication-title: Neuron
  doi: 10.1016/S0896-6273(03)00597-X
  contributor:
    fullname: EH Baeg
– volume-title: Working Memory in Perspective
  year: 2001
  ident: BFnature14445_CR3
  contributor:
    fullname: J Andrade
– volume: 61
  start-page: 331
  year: 1989
  ident: BFnature14445_CR29
  publication-title: J. Neurophysiol.
  doi: 10.1152/jn.1989.61.2.331
  contributor:
    fullname: S Funahashi
– volume: 171
  start-page: 116
  year: 2006
  ident: BFnature14445_CR34
  publication-title: Behav. Brain Res.
  doi: 10.1016/j.bbr.2006.03.030
  contributor:
    fullname: HL Sloan
– volume: 459
  start-page: 534
  year: 2009
  ident: BFnature14445_CR37
  publication-title: Nature
  doi: 10.1038/nature08010
  contributor:
    fullname: EV Lubenov
– volume: 321
  start-page: 140
  year: 2008
  ident: BFnature14445_CR18
  publication-title: Science
  doi: 10.1126/science.1157086
  contributor:
    fullname: KB Kjelstrup
– volume: 252
  start-page: 1177
  year: 1991
  ident: BFnature14445_CR23
  publication-title: Science
  doi: 10.1126/science.252.5009.1177
  contributor:
    fullname: AK Engel
– volume: 4
  start-page: 829
  year: 2003
  ident: BFnature14445_CR5
  publication-title: Nature Rev. Neurosci.
  doi: 10.1038/nrn1201
  contributor:
    fullname: A Baddeley
– volume: 33
  start-page: 14211
  year: 2013
  ident: BFnature14445_CR39
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.2378-13.2013
  contributor:
    fullname: PK O’Neill
– volume: 199
  start-page: 222
  year: 2009
  ident: BFnature14445_CR16
  publication-title: Behav. Brain Res.
  doi: 10.1016/j.bbr.2008.11.045
  contributor:
    fullname: BG Burton
– volume: 27
  start-page: 3029
  year: 2008
  ident: BFnature14445_CR35
  publication-title: Eur. J. Neurosci.
  doi: 10.1111/j.1460-9568.2008.06284.x
  contributor:
    fullname: Y Izaki
– volume: 14
  start-page: 249
  year: 2008
  ident: BFnature14445_CR31
  publication-title: Neurotox. Res.
  doi: 10.1007/BF03033814
  contributor:
    fullname: JK Seamans
– volume: 175
  start-page: 329
  year: 2006
  ident: BFnature14445_CR12
  publication-title: Behav. Brain Res.
  doi: 10.1016/j.bbr.2006.09.002
  contributor:
    fullname: GW Wang
– volume: 75
  start-page: 700
  year: 2012
  ident: BFnature14445_CR24
  publication-title: Neuron
  doi: 10.1016/j.neuron.2012.06.014
  contributor:
    fullname: MF Carr
– volume: 8
  start-page: 243
  year: 2001
  ident: BFnature14445_CR6
  publication-title: Learn. Mem.
  doi: 10.1101/lm.40301
  contributor:
    fullname: GI de Zubicaray
– volume: 3
  start-page: e402
  year: 2005
  ident: BFnature14445_CR9
  publication-title: PLoS Biol.
  doi: 10.1371/journal.pbio.0030402
  contributor:
    fullname: MW Jones
– volume: 464
  start-page: 763
  year: 2010
  ident: BFnature14445_CR10
  publication-title: Nature
  doi: 10.1038/nature08855
  contributor:
    fullname: T Sigurdsson
– volume: 4
  start-page: 528
  year: 2004
  ident: BFnature14445_CR7
  publication-title: Cogn. Affect. Behav. Neurosci.
  doi: 10.3758/CABN.4.4.528
  contributor:
    fullname: CE Curtis
– volume: 54
  start-page: 91
  year: 1993
  ident: BFnature14445_CR33
  publication-title: Behav. Brain Res.
  doi: 10.1016/0166-4328(93)90051-Q
  contributor:
    fullname: C Shaw
– volume: 49
  start-page: 231
  year: 1992
  ident: BFnature14445_CR32
  publication-title: Behav. Brain Res.
  doi: 10.1016/S0166-4328(05)80169-X
  contributor:
    fullname: DC Rogers
– volume: 30
  start-page: 1777
  year: 2010
  ident: BFnature14445_CR19
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.4681-09.2010
  contributor:
    fullname: S Royer
– volume: 33
  start-page: 8079
  year: 2013
  ident: BFnature14445_CR42
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.5458-12.2013
  contributor:
    fullname: RW Komorowski
– volume: 10
  start-page: 687
  year: 1989
  ident: BFnature14445_CR46
  publication-title: Europhys. Lett.
  doi: 10.1209/0295-5075/10/7/014
  contributor:
    fullname: JK Anlauf
– volume: 20
  start-page: L745
  year: 1987
  ident: BFnature14445_CR48
  publication-title: J. Phys. A Math. Gen.
  doi: 10.1088/0305-4470/20/11/013
  contributor:
    fullname: W Krauth
– volume: 100
  start-page: 1407
  year: 2008
  ident: BFnature14445_CR43
  publication-title: J. Neurophysiol.
  doi: 10.1152/jn.90248.2008
  contributor:
    fullname: EM Meyers
– volume: 497
  start-page: 585
  year: 2013
  ident: BFnature14445_CR22
  publication-title: Nature
  doi: 10.1038/nature12160
  contributor:
    fullname: M Rigotti
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Snippet Spatial working memory, the caching of behaviourally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. Although the...
Spatial working memory, the caching of behaviorally relevant spatial cues on a timescale of seconds, is a fundamental constituent of cognition. While the...
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StartPage 309
SubjectTerms 631/378/1595/1554
631/378/1595/1637
631/378/1595/2618
64/60
9/10
9/26
9/30
Action Potentials
Afferent Pathways - physiology
Animals
Brain
Cognition & reasoning
Cues
Hippocampus (Brain)
Hippocampus - cytology
Hippocampus - physiology
Humanities and Social Sciences
Male
Memory
Memory, Short-Term - physiology
Mice
Models, Neurological
multidisciplinary
Optogenetics
Physiological aspects
Prefrontal cortex
Prefrontal Cortex - cytology
Prefrontal Cortex - physiology
Science
Short-term memory
Space Perception - physiology
Spatial Memory - physiology
Title Hippocampal–prefrontal input supports spatial encoding in working memory
URI https://link.springer.com/article/10.1038/nature14445
https://www.ncbi.nlm.nih.gov/pubmed/26053122
https://www.proquest.com/docview/1690371760
https://search.proquest.com/docview/1690217543
https://pubmed.ncbi.nlm.nih.gov/PMC4505751
Volume 522
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