Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis - Song, SungWon; Miranda, Carlos J; Braun, Lyndsey; Meyer, Kathrin; Frakes, Ashley E; Ferraiuolo, Laura; Likhite, Shibi; Bevan, Adam K; Foust, Kevin D; McConnell, Michael J; Walker, Christopher M; Kaspar, Brian K (Nature medicine, 2016)
Keywords: 13; 13/1; 13/100; 42; 42/44; 42/89; 631/378/371; 631/378/87; Aged; Aged, 80 and over; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Amyotrophic Lateral Sclerosis - pathology; Analysis; Animals; Astrocytes - metabolism; Astrocytes - pathology; Biomedicine; Cadaver; Cancer Research; Cell Death - genetics; Disease Models, Animal; Female; Gene Expression Regulation; Genetic aspects; Histocompatibility antigens; Histocompatibility Antigens Class I - biosynthesis; Histocompatibility Antigens Class I - genetics; HLA histocompatibility antigens; Humans; Immune system; Infectious Diseases; Major histocompatibility complex; Male; Metabolic Diseases; Mice; Mice, Transgenic; Middle Aged; Molecular Medicine; Mortality; Motor Neurons - pathology; Mutation; Neurons; Neurosciences; Pathogenesis; Receptors, KIR3DL2 - genetics; Superoxide Dismutase - genetics; Toxicity; Ohio