Evaluation of the fusion partner cell line SPYMEG for obtaining human monoclonal antibodies against influenza B virus

• Published in: Journal of Veterinary Medical Science Vol. 80; no. 6; pp. 1020 - 1024
• Main Authors: SONI, Priyanka, YASUHARA, Atsuhiro, TAKENAGA, Toru, IWATSUKI-HORIMOTO, Kiyoko, URAKI, Ryuta, ITO, Mutsumi, SASAKI, Tadahiro, IKUTA, Kazuyoshi, YAMAYOSHI, Seiya, KAWAOKA, Yoshihiro
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2018; The Japanese Society of Veterinary Science
• Subjects: Animals; Antibodies, Monoclonal - immunology; Antibodies, Viral - immunology; Cell Line; Hemagglutinin Glycoproteins, Influenza Virus; human monoclonal antibody; Humans; hybridoma; Hybridomas - immunology; Influenza B virus; Leukocytes, Mononuclear; Mice; SPYMEG; Virology; SPYMEG; hybridoma; human monoclonal antibody; influenza B virus

Influenza B virus has been known to infect humans and other animals, including seals. Vaccination efficacy varies across seasons. Human monoclonal antibodies (mAbs) can be useful for developing novel vaccines, guided by epitope analysis, and can be used therapeutically. Hybridoma technology has been...