Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C - Matsuda, Mami; Hirai-Yuki, Asuka; Kotani, Osamu; Kataoka, Michiyo; Zheng, Xin; Yamane, Daisuke; Yokoyama, Masaru; Ishii, Koji; Muramatsu, Masamichi; Suzuki, Ryosuke (PLoS pathogens, 2024)
Keywords: Analysis; Animals; Antiviral agents; Antiviral drugs; Biological response modifiers; Biology and life sciences; Care and treatment; Cytotoxicity; Dengue fever; Diagnosis; Dopamine; Dopamine D2 receptors; Dosage and administration; Drug development; Drugs; Food contamination & poisoning; Genomes; Genotype & phenotype; Health aspects; Hepatitis; Hepatitis A; Hepatitis A virus; Hepatitis A virus - genetics; Hepatitis A virus - metabolism; Hepatitis C; Infection; Internal ribosome entry site; Loxapine; Medical research; Medicine and health sciences; Medicine, Experimental; Methicillin; Mice; Molecular dynamics; Mutation; Phenothiazine; Physical Sciences; Protein 2C; Protein Biosynthesis; Proteins; Receptors; Replication; Research and Analysis Methods; Ribonucleic acid; RNA; RNA - metabolism; RNA polymerase; RNA, Viral - genetics; RNA, Viral - metabolism; Schizophrenia; Staphylococcus infections; Viral proteins; Viral Proteins - metabolism; Virus Replication - genetics; Viruses; Japan; United States--US