Molecular cloning, characterization, and immunolocalization of two lactate dehydrogenase homologous genes from Taenia solium

• Published in: Parasitology research (1987) Vol. 109; no. 3; pp. 567 - 574
• Main Authors: Du, Wuying, Hu, Fengyu, Yang, Yabo, Hu, Dong, Hu, Xuchu, Yu, Xinbing, Xu, Jin, Dai, Jialin, Liao, Xinjiang, Huang, Jiang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.09.2011; Springer; Springer Nature B.V
• Subjects: Amino acid sequence; Amino acids; Analysis; Animals; Antibodies, Helminth - blood; Antigenic determinants; Antigens; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Blotting, Western; Cestode diseases; Cloning; Cloning, Molecular; Conserved sequence; Cross Reactions; Danio rerio; Dehydrogenases; Epitopes; Epitopes - immunology; Escherichia coli; Escherichia coli - genetics; Fundamental and applied biological sciences. Psychology; General aspects; General aspects and techniques. Study of several systematic groups. Models; Genes; Genetic research; Humans; Immunodiagnosis; Immunology; Invertebrates; L-Lactate dehydrogenase; L-Lactate Dehydrogenase - analysis; L-Lactate Dehydrogenase - genetics; L-Lactate Dehydrogenase - immunology; Lactic acid; Localization; Lymphocytes B; Medical Microbiology; Microbiology; Nucleotide sequence; Original Paper; Physicochemical properties; Praziquantel; Rats; Rats, Sprague-Dawley; Schistosoma japonicum; Sequence Homology, Amino Acid; Sus scrofa; Swine; Taenia solium; Taenia solium - enzymology; Taenia solium - genetics; Tegument; Xenopus laevis; China; Artemether; Schistosoma Japonicum; Cysticercosis; Praziquantel; Gossypol; Gene; Helmintha; Plathelmintha; Parasite; Cestoda; Invertebrata; Molecular cloning; Taenia solium

Two novel genes encoding lactate dehydrogenase A (LDHA) and B (LDHB) homologues, respectively, were identified from the cDNA libraries of adult Taenia solium ( T. solium ). The two deduced amino acid sequences both show more than 50% identity to the homologues for Danio rerio , Xenopus laevis , Schi...