Role of Inflammation in Atrial Fibrillation Pathophysiology and Management

• Published in: Circulation Journal Vol. 79; no. 3; pp. 495 - 502
• Main Authors: Nattel, Stanley, Wagoner, David R. Van, Harada, Masahide
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Circulation Society 2015
• Subjects: Animals; Anti-inflammatory drugs; Apoptosis; Atrial fibrillation; Atrial Fibrillation - blood; Atrial Fibrillation - physiopathology; Atrial Fibrillation - therapy; Biomarkers; Blood Coagulation; Fibrosis; Humans; Inflammation - blood; Inflammation - pathology; Inflammation - physiopathology; Inflammation Mediators - blood; Inflammatory markers; Oxidative Stress; Thrombogenesis

Atrial fibrillation (AF) is the most common clinically relevant arrhythmia, but the methods available for treating AF and its complications (of which the most important is thrombogenesis), as well as for assessing AF risk and underlying pathophysiology, are largely limited. Emerging evidence suggest...