Hierarchical Organization of Gamma and Theta Oscillatory Dynamics in Schizophrenia

• Published in: Biological psychiatry (1969) Vol. 71; no. 10; pp. 873 - 880
• Main Authors: Kirihara, Kenji, Rissling, Anthony J., Swerdlow, Neal R., Braff, David L., Light, Gregory A.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.05.2012; Elsevier
• Subjects: Acoustic Stimulation; Adult; Adult and adolescent clinical studies; Auditory steady-state response; Biological and medical sciences; Brain Waves - physiology; Case-Control Studies; Cognition - physiology; cross-frequency coupling; Electroencephalography; Female; gamma oscillations; Humans; Male; Medical sciences; Middle Aged; neural oscillations; Neuropsychological Tests; Psychiatric/Mental Health; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Schizophrenia; Schizophrenia - physiopathology; theta oscillations; Theta Rhythm - physiology; Auditory steady-state response; schizophrenia; neural oscillations; theta oscillations; cross-frequency coupling; gamma oscillations; Psychosis; Hearing; Oscillation; Schizophrenia; Perception

Schizophrenia patients have deficits across a broad range of important cognitive and clinical domains. Synchronization of oscillations in the gamma frequency range (∼40 Hz) is associated with many normal cognitive functions and underlies at least some of the deficits observed in schizophrenia patien...