Reptilian heart development and the molecular basis of cardiac chamber evolution

• Published in: Nature (London) Vol. 461; no. 7260; pp. 95 - 98
• Main Authors: Koshiba-Takeuchi, Kazuko, Mori, Alessandro D., Kaynak, Bogac L., Cebra-Thomas, Judith, Sukonnik, Tatyana, Georges, Romain O., Latham, Stephany, Beck, Laural, Henkelman, R. Mark, Black, Brian L., Olson, Eric N., Wade, Juli, Takeuchi, Jun K., Nemer, Mona, Gilbert, Scott F., Bruneau, Benoit G.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.09.2009; Nature Publishing Group
• Subjects: Animal development; Animals; Biological and medical sciences; Biological evolution; Chick Embryo; Evolution; Evolution, Molecular; Evolutionary biology; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Developmental; Genetics of eukaryotes. Biological and molecular evolution; Heart; Heart - anatomy & histology; Heart - embryology; Humanities and Social Sciences; letter; Lizards - anatomy & histology; Lizards - embryology; Lizards - genetics; Mice; Molecules; multidisciplinary; Organogenesis; Physiological aspects; Reptiles; Reptiles & amphibians; Rodents; Science; T-Box Domain Proteins - deficiency; T-Box Domain Proteins - genetics; T-Box Domain Proteins - metabolism; Turtles - anatomy & histology; Turtles - embryology; Turtles - genetics; United States; Heart; Embryonic development; Molecular evolution; Vertebrata; Biological evolution; Histology; Reptilia

Heart to heart Birds, mammals and crocodiles have hearts with two separate ventricles, servicing separate pulmonary and systemic circulations. Amphibians have just one ventricle, but in most reptiles, the situation is unclear. A new embryological study of a lizard (the green anole) and a turtle (the...