MR vascular fingerprinting: A new approach to compute cerebral blood volume, mean vessel radius, and oxygenation maps in the human brain

• Published in: NeuroImage (Orlando, Fla.) Vol. 89; pp. 262 - 270
• Main Authors: Christen, T., Pannetier, N.A., Ni, W.W., Qiu, D., Moseley, M.E., Schuff, N., Zaharchuk, G.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.04.2014; Elsevier; Elsevier Limited
• Subjects: Acquisitions & mergers; Adult; Biological and medical sciences; Blood oxygen saturation; Blood Volume Determination; Brain - blood supply; Cerebral blood volume; Dictionaries; Female; Fingerprint; Fundamental and applied biological sciences. Psychology; Health Insurance Portability & Accountability Act 1996-US; Humans; Magnetic Resonance Imaging; Male; Mathematical models; Medical research; Middle Aged; Models, Theoretical; Numerical simulation; Oxygen; Vertebrates: nervous system and sense organs; Vessel size imaging; Numerical simulation; Cerebral blood volume; Blood oxygen saturation; Fingerprint; Vessel size imaging; Magnetic resonance imaging; Human; Central nervous system; Nuclear magnetic resonance imaging; Encephalon; Blood volume; Imaging; Blood vessel; Circulatory system

In the present study, we describe a fingerprinting approach to analyze the time evolution of the MR signal and retrieve quantitative information about the microvascular network. We used a Gradient Echo Sampling of the Free Induction Decay and Spin Echo (GESFIDE) sequence and defined a fingerprint as...