Transcriptome analysis of controlled and therapy-resistant childhood asthma reveals distinct gene expression profiles - Persson, Helena; Kwon, Andrew T.; Ramilowski, Jordan A.; Silberberg, Gilad; Söderhäll, Cilla; Orsmark-Pietras, Christina; Nordlund, Björn; Konradsen, Jon R.; de Hoon, Michiel J.L.; Melén, Erik; Hayashizaki, Yoshihide; Hedlin, Gunilla; et al. (Journal of allergy and clinical immunology, 2015)
Keywords: Adolescent; Allergy and Immunology; Asthma; Asthma - drug therapy; Asthma - genetics; Asthma - pathology; Case-Control Studies; Child; Child, Preschool; childhood asthma; Drug Resistance - genetics; Female; Gene expression; Gene Expression Profiling; Genome-Wide Association Study; Glucocorticoids - therapeutic use; Humans; JNK Mitogen-Activated Protein Kinases - genetics; long noncoding RNA; Male; Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics; peripheral blood leukocytes; Receptors, Glucocorticoid - genetics; RNA polymerase; RNA, Messenger - genetics; Severity of Illness Index; Therapy-resistant asthma; Transcriptome; MARA; peripheral blood leukocytes; CAGE; Therapy-resistant asthma; transcriptome; GO; GLM; RORA; childhood asthma; MAPK; SA; TC; TF; CTRL; SNP; TSS; long noncoding RNA; LD; KEGG; lincRNA; NK; CA; Generalized linear model; Linkage disequilibrium; Long intergenic noncoding RNA; Tag cluster; Cap Analysis of Gene Expression; Transcription start site; Healthy control subject; Transcription factor; Gene Ontology; Motif Activity Response Analysis; Kyoto Encyclopedia of Genes and Genomes; Mitogen-activated protein kinase; RAR-related orphan receptor A; Natural killer; Controlled persistent asthma; Single nucleotide polymorphism