Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures

A polydimethylsiloxane microchannel featuring sidewall sharp‐edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp‐edge structures and the thin glass slide gener...

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Bibliographic Details
Published inSmall (Weinheim an der Bergstrasse, Germany) Vol. 12; no. 37; pp. 5120 - 5125
Main Authors Ozcelik, Adem, Nama, Nitesh, Huang, Po-Hsun, Kaynak, Murat, McReynolds, Melanie R., Hanna-Rose, Wendy, Huang, Tony Jun
Format Journal Article
LanguageEnglish
Published Germany Blackwell Publishing Ltd 01.10.2016
Wiley Subscription Services, Inc
Subjects
Acoustic streaming
Acoustics - instrumentation
acoustofluidics
Animals
C. elegans
Caenorhabditis elegans - cytology
Channels
Glass
HeLa Cells
Humans
Microchannels
microfluidics
Nanotechnology
Neurons - cytology
Organisms
Oscillating
Rotation
rotational manipulations
Transducers
C. elegans
acoustofluidics
microfluidics
rotational manipulations
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Summary:A polydimethylsiloxane microchannel featuring sidewall sharp‐edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp‐edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in‐plane and out‐of‐plane.
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content type line 23
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201601760