Tissue factor–bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo - Park, Jin-Ah; Sharif, Asma S.; Tschumperlin, Daniel J.; Lau, Laurie; Limbrey, Rachel; Howarth, Peter; Drazen, Jeffrey M. (Journal of allergy and clinical immunology, 2012)
Keywords: Adult; Age; Aged; Airway management; Airway Remodeling; Allergy and Immunology; Angiogenesis; Asthma; Asthma - immunology; Asthma - pathology; Atmospheric pressure; Biological and medical sciences; Biopsy; blood coagulation; Bronchi - immunology; Bronchi - pathology; bronchial epithelium; Bronchoalveolar Lavage Fluid - immunology; bronchoconstriction; Bronchoconstriction - immunology; Cells, Cultured; Cellular Microenvironment - immunology; Chronic obstructive pulmonary disease, asthma; epithelial cells; Epithelial Cells - immunology; epithelium; exosomes; Exosomes - immunology; Fundamental and applied biological sciences. Psychology; Fundamental immunology; gene expression regulation; Humans; immunohistochemistry; Immunopathology; in vivo studies; Kinases; mechanotransduction; Mechanotransduction, Cellular; Medical sciences; messenger RNA; Microscopy; Middle Aged; patients; Pneumology; Proteins; Respiratory distress syndrome; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; secretion; Thromboplastin - genetics; Thromboplastin - metabolism; tissue factor; ultracentrifugation; water; Young Adult; NHBECs; tissue factor; mechanotransduction; BALF; PKC; CM; bronchoconstriction; Bis 1; EBBs; Asthma; TF; exosomes; bronchial epithelium; GAPDH; TEM; ALI; Protein kinase C; Bisindoylmaleimide 1; Normal human bronchial epithelial cells; Conditioned media; Air-liquid interface; Glyceraldehyde-3-phosphate; Transmission electron microscopy; Bronchoalveolar lavage fluid; Endobronchial biopsies; Human; Lung disease; Immunopathology; Respiratory disease; Secretion; Tissue factor; Bronchus; Epithelium; Respiratory system; In vitro; Respiratory tract; In vivo; Bronchoconstriction; Immunology; Exosome; Bronchus disease; Epithelial cell; Obstructive pulmonary disease