Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model - Wang, Xiaoxin X.; Jiang, Tao; Shen, Yan; Caldas, Yupanqui; Miyazaki-Anzai, Shinobu; Santamaria, Hannah; Urbanek, Cydney; Solis, Nathaniel; Scherzer, Pnina; Lewis, Linda; Gonzalez, Frank J.; Adorini, Luciano; et al. (Diabetes (New York, N.Y.), 2010)
Keywords: Animals; Associated diseases and complications; Binding proteins; Biological and medical sciences; Care and treatment; Cholesterol; Complications; Complications and side effects; Crosses, Genetic; Development and progression; Diabetes; Diabetes Mellitus, Experimental - pathology; Diabetes Mellitus, Experimental - physiopathology; Diabetes Mellitus, Type 1 - pathology; Diabetes Mellitus, Type 1 - physiopathology; Diabetes. Impaired glucose tolerance; Diabetic nephropathies; Diabetic Nephropathies - pathology; Diabetic Nephropathies - physiopathology; Diabetic Nephropathies - prevention & control; Diabetic nephropathy; DNA Primers; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Foam Cells - pathology; Genetic aspects; Glucose; Growth factors; House mouse; Hyperglycemia; Kidney - pathology; Kidney - physiopathology; Kidney diseases; Kidney Glomerulus - pathology; Kidneys; Lipids; Macrophages - pathology; Male; Medical sciences; Metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microscopy; Nephrology. Urinary tract diseases; Oxidative stress; Pathogenesis; Physiological aspects; Polymerase Chain Reaction; Proteins; Receptors, Cytoplasmic and Nuclear - deficiency; Receptors, Cytoplasmic and Nuclear - genetics; Receptors, Cytoplasmic and Nuclear - physiology; Research design; Risk factors; Sterols; Type 1 diabetes; Urinary system involvement in other diseases. Miscellaneous; United States; St Louis Missouri; United States--US; Endocrinopathy; Kidney disease; Farnesoid X receptor; Immunopathology; Concomitant disease; Urinary system disease; Type 1 diabetes; Deficiency; Autoimmune disease; Diabetic nephropathy; Models