Transcriptome analysis of the aortic coarctation area

• Published in: Journal of Molecular and Cellular Cardiology Plus (Online) Vol. 10; p. 100094
• Main Authors: Ellegård, Rada, Malm, Torsten, Weismann, Constance G., Fernlund, Eva, Nordén Björnlert, Anneli, Klang Årstrand, Hanna, Ellnebo-Svedlund, Katarina, Gunnarsson, Cecilia
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2024; Elsevier
• Subjects: Cardiology and Cardiovascular Disease; Clinical Medicine; CoA, RNAseq; Coarctation of aorta; Ductus; Kardiologi och kardiovaskulära sjukdomar; Klinisk medicin; Medical and Health Sciences; Medicin och hälsovetenskap; Transcriptome; Ductus; Coarctation of aorta; CoA, RNAseq; Transcriptome; CoA; RNAseq
• ISSN: 2772-9761; 2772-9761
• DOI: 10.1016/j.jmccpl.2024.100094

Coarctation of the aorta (CoA) is a relatively common congenital heart defect. The underlying causes are not known, but a combination of genetic factors and abnormalities linked to embryonic development is suspected. There are only a few studies of the underlying molecular mechanisms in CoA. The aim...