The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children - Porritt, Rebecca A.; Binek, Aleksandra; Paschold, Lisa; Rivas, Magali Noval; McArdle, Angela; Yonker, Lael M.; Alter, Galit; Chandnani, Harsha K.; Lopez, Merrick; Fasano, Alessio; Van Eyk, Jennifer E.; Binder, Mascha; et al. (The Journal of clinical investigation, 2021)
Keywords: Adaptive Immunity; Adolescent; Antigens; Autoantibodies; Autoimmunity; B-cell receptor; Biomarkers; Biomarkers - metabolism; Biomedical research; Case-Control Studies; Cell activation; Child; Child, Preschool; Children; Cohort Studies; Complement activation; Coronaviruses; COVID-19; COVID-19 - complications; COVID-19 - genetics; COVID-19 - immunology; COVID-19 - metabolism; Cytokine Release Syndrome - immunology; Cytokine storm; Disease; Female; Genetic aspects; Health aspects; Humans; Immune response; Immune response (humoral); Immunoglobulin G; Immunopathogenesis; Infant; Inflammation; Inflammation - immunology; Intensive care; Leukocytes (neutrophilic); Lymphocytes; Lymphocytes T; Male; Mucocutaneous Lymph Node Syndrome - genetics; Mucocutaneous Lymph Node Syndrome - immunology; Mucocutaneous Lymph Node Syndrome - metabolism; Multisystem inflammatory syndrome in children; Neutrophil Activation; Neutrophils; Pandemics; Pathogenesis; Patients; Pediatric research; Pediatrics; Peptides; Plasma; Proteins; Proteomics; Receptors, Antigen, B-Cell - genetics; RNA-Seq; Severe acute respiratory syndrome coronavirus 2; Severity of Illness Index; Systemic Inflammatory Response Syndrome - genetics; Systemic Inflammatory Response Syndrome - immunology; Systemic Inflammatory Response Syndrome - metabolism; T cell receptors; Variable region; United States; COVID-19; Inflammation; Cytokines; Autoimmune diseases; Cellular immune response