Dietary organic acids ameliorate high stocking density stress-induced intestinal inflammation through the restoration of intestinal microbiota in broilers

• Published in: Journal of animal science and biotechnology Vol. 13; no. 1; p. 124
• Main Authors: Dai, Dong, Qi, Guanghai, Wang, Jing, Zhang, Haijun, Qiu, Kai, Han, Yanming, Wu, Yuanyuan, Wu, Shugeng
• Format: Journal Article
• Language: English
• Published: London BioMed Central 14.11.2022; BMC
• Subjects: Abundance; Acid production; Animal production; Bacteroidetes; Bioengineering; Birds; blood serum; Broiler; Cholesterol; Corticosterone; Cytokines; Density; Diet; Digestive system; Enzymes; Fatty acids; Feed additives; Gastrointestinal tract; Gene expression; growth performance; High stocking density; IL-1β; Inflammation; Interleukin 10; Intestinal inflammation; Intestinal microbiota; Intestinal microflora; intestinal microorganisms; Intestine; intestines; Lipopolysaccharides; males; Microbial activity; Microbiota; Microorganisms; MyD88 protein; necrosis; neoplasms; NF-κB protein; Organic acid; Organic acids; Poultry; Proteins; short chain fatty acids; Short-chain fatty acid; Signal transduction; Signaling; Small intestine; Stocking; TLR4 protein; Toll-like receptors; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Zonula occludens-1 protein; United States > US; China; Japan

BackgroundHigh stocking density (HSD) stress has detrimental effects on growth performance, intestinal barrier function, and intestinal microbiota in intensive animal production. Organic acids (OA) are widely used as feed additives for their ability to improve growth performance and intestinal healt...