Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis - van Es, Michael A; Veldink, Jan H; Saris, Christiaan G J; Blauw, Hylke M; van Vught, Paul W J; Birve, Anna; Lemmens, Robin; Schelhaas, Helenius J; Groen, Ewout J N; Huisman, Mark H B; van der Kooi, Anneke J; de Visser, Marianne; et al. (Nature genetics, 2009)
Keywords: Agriculture; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Animal Genetics and Genomics; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Brain research; Cancer Research; Care and treatment; Cerebrospinal fluid. Meninges. Spinal cord; Charitable foundations; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 9; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dementia disorders; Disease Susceptibility; Fundamental and applied biological sciences. Psychology; Gene Function; Genetic aspects; Genetics; Genetics of eukaryotes. Biological and molecular evolution; Genome, Human; Genome-Wide Association Study; Health aspects; Human Genetics; Humans; Identification and classification; letter; Medical research; Medical sciences; Muscular dystrophy; Nervous system (semeiology, syndromes); Neurological disorders; Neurology; Polymorphism, Single Nucleotide; Quality control; Quantitative trait loci; Risk factors; Single nucleotide polymorphisms; Statistical analysis; Netherlands; Germany; Nervous system diseases; Sporadic; Central nervous system disease; Amyotrophic lateral sclerosis; Degenerative disease; Identification; Locus; Spinal cord disease