Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

• Published in: Nature reviews. Immunology Vol. 21; no. 10; pp. 626 - 636
• Main Authors: Tregoning, John S., Flight, Katie E., Higham, Sophie L., Wang, Ziyin, Pierce, Benjamin F.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.10.2021; Nature Publishing Group
• Subjects: 631/250/590; 631/326/596/4130; Adverse and side effects; Biomedical and Life Sciences; Biomedicine; Clinical Trials as Topic; Control; Coronaviruses; COVID-19; COVID-19 vaccines; COVID-19 Vaccines - administration & dosage; COVID-19 Vaccines - adverse effects; COVID-19 Vaccines - classification; COVID-19 Vaccines - immunology; Drugs; Epidemics; Health Services Accessibility; Humans; Immunology; Medical research; Medicine, Experimental; Pandemics; Progress; SARS-CoV-2 - classification; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Severe acute respiratory syndrome coronavirus 2; United Kingdom; Vaccine efficacy; Vaccines; Viruses; World Health Organization; United Kingdom

Where 2020 saw the development and testing of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has seen vaccine rollout in many countries. In this Progress article, we provide a snapshot of ongoing vaccine efficacy studies...