Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase

• Published in: The EMBO journal Vol. 26; no. 6; pp. 1713 - 1725
• Main Authors: Shinzawa-Itoh, Kyoko, Aoyama, Hiroshi, Muramoto, Kazumasa, Terada, Hirohito, Kurauchi, Tsuyoshi, Tadehara, Yoshiki, Yamasaki, Akiko, Sugimura, Takashi, Kurono, Sadamu, Tsujimoto, Kazuo, Mizushima, Tsunehiro, Yamashita, Eiki, Tsukihara, Tomitake, Yoshikawa, Shinya
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 21.03.2007; Blackwell Publishing Ltd; Nature Publishing Group
• Subjects: Absorptiometry, Photon; Anatomy & physiology; Animals; Binding sites; Binding Sites - genetics; Cattle; Chromatography, Gas; Cytochrome; cytochrome c oxidase; Electron Transport Complex IV - chemistry; Electron Transport Complex IV - metabolism; Electron Transport Complex IV - physiology; Evolution, Molecular; fatty acid structure; Fatty acids; Heart; Lipids; Lipids - analysis; Mass spectrometry; Membranes; Models, Molecular; Molecular biology; Molecular Structure; Myocardium - enzymology; Oleic Acids - analysis; Paracoccus denitrificans; Paracoccus denitrificans - chemistry; phospholipids; Proteins; Tandem Mass Spectrometry; X-ray structural analysis; X-rays

All 13 lipids, including two cardiolipins, one phosphatidylcholine, three phosphatidylethanolamines, four phosphatidylglycerols and three triglycerides, were identified in a crystalline bovine heart cytochrome c oxidase (CcO) preparation. The chain lengths and unsaturated bond positions of the fatty...