TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue - Baskaran, P; Krishnan, V; Fettel, K; Gao, P; Zhu, Z; Ren, J; Thyagarajan, B (International Journal of Obesity, 2017)
Keywords: 13; 13/106; 13/95; 631/80/458; 631/80/458/1275; 631/80/86; 64/60; 692/699/2743/393; 82; 82/80; Acetylation; Acetylation - drug effects; Adipose tissue; Adipose tissue (brown); Adipose Tissue, Brown - drug effects; Adipose Tissue, Brown - metabolism; Animals; Anti-Obesity Agents - pharmacology; Body fat; Body weight loss; Calcium (intracellular); Calcium ions; Calcium permeability; Capsaicin; Capsaicin - pharmacology; Capsaicin receptors; Capsazepine; Care and treatment; Chelation; Deacetylation; Diet; Diet, High-Fat - adverse effects; Dietary supplements; Disease Models, Animal; DNA-Binding Proteins - metabolism; Energy; Energy expenditure; Energy intake; Energy Intake - physiology; Energy metabolism; Energy Metabolism - physiology; Epidemiology; Experiments; Genetic aspects; Glucagon; Glucagon-like peptide 1; Glucose tolerance; Health Promotion and Disease Prevention; High fat diet; Hypercholesterolemia; Hypertension; Immunoblotting; Internal Medicine; Intolerance; Lipolysis; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolism; Mice; Mice, Knockout; Nutritional aspects; Obesity; Obesity - drug therapy; Obesity - metabolism; Obesity - prevention & control; original-article; Peroxisome proliferator-activated receptors; Pharmacy; Phosphorylation; Proteins; Public Health; Quotients; Receptors; Sirtuin 1 - metabolism; Thermogenesis; Thermogenesis - drug effects; Transcription Factors - metabolism; TRPV Cation Channels - agonists; TRPV Cation Channels - metabolism; Up-Regulation; Weight control; Weight loss; Zinc finger proteins; United States--US