Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryos
Background Recent technological development allows nearly complete replacement of the cytoplasm of egg/embryo, eliminating the transmission of undesired defective mitochondria (mutated mitochondrial DNA: mtDNA) for patients with inherited mitochondrial diseases, which is called mitochondrial replace...
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Published in | Reproductive medicine and biology Vol. 17; no. 4; pp. 421 - 433 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Japan
John Wiley & Sons, Inc
01.10.2018
John Wiley and Sons Inc Wiley |
Subjects | |
Online Access | Get full text |
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