Unrelated cord blood transplantation in CML: Japan Cord Blood Bank Network analysis

• Published in: Bone marrow transplantation (Basingstoke) Vol. 42; no. 4; pp. 241 - 251
• Main Authors: Nagamura-Inoue, T, Kai, S, Azuma, H, Takanashi, M, Isoyama, K, Kato, K, Takahashi, S, Taniguchi, S, Miyamura, K, Aoki, K, Hidaka, M, Nagamura, F, Tojo, A, Fang, X M, Kato, S
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.08.2008; Nature Publishing Group
• Subjects: Adolescent; Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blast crisis; Blood; Blood banks; Bone marrow; Bone marrow, stem cells transplantation. Graft versus host reaction; Care and treatment; Cell Biology; Child; Child, Preschool; Chronic myeloid leukemia; Cord blood; Cord Blood Stem Cell Transplantation - mortality; Diagnosis; Disease-Free Survival; Dosage; Female; Fetal blood; Hematologic and hematopoietic diseases; Hematology; Humans; Infant; Internal Medicine; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Leukocytes (neutrophilic); Male; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Multivariate analysis; Network analysis; Neutrophils; original-article; Patients; Platelets; Public Health; Recovery; Recurrence; Risk Factors; Stem cell transplantation; Stem Cells; Survival; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Transplantation; Transplants & implants; Asia; Japan; CML; unrelated cord blood transplantation; cord blood cells; Hematology; Unrelated donor; Stem cell; Hematopoietic cell; Homograft; Chronic myelogenous leukemia; Malignant hemopathy; Blood; Myeloproliferative syndrome; Blood cell; Network; Graft; Blood bank; Umbilical cord; Cancer

We analysed 86 patients with CML who received unrelated cord blood transplantation (UCBT), identified through a registry of the Japan Cord Blood Bank Network. At transplantation, the median patient age was 39 years (range, 1–67 years); 38 patients were in chronic phase (CP), 13 in the accelerated ph...