Osteopontin at the Crossroads of Inflammation and Tumor Progression

Complex interactions between tumor and host cells regulate systemic tumor dissemination, a process that begins early at the primary tumor site and goes on until tumor cells detach themselves from the tumor mass and start migrating into the blood or lymphatic vessels. Metastatic cells colonize the ta...

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Published inMediators of inflammation Vol. 2017; no. 2017; pp. 1 - 22
Main Authors Cantaluppi, Vincenzo, Dianzani, Umberto, Aspesi, Anna, Chiocchetti, Annalisa, Gentilli, Sergio, Garzaro, Massimiliano, Quaglia, Marco, Vaschetto, Rosanna, Clemente, Nausicaa, Salmi, Livia, Raineri, Davide, Castello, Luigi Mario, Navalesi, Paolo
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2017
Hindawi
Hindawi Limited
Wiley
Subjects
Angiogenesis
Animals
Apoptosis
Cancer therapies
Cell adhesion & migration
Colleges & universities
Cytokines
Development and progression
Disease Progression
Extracellular matrix
Fibroblasts
Health aspects
Health sciences
Humans
Inflammation
Inflammation - genetics
Inflammation - metabolism
Kinases
Neoplasm Metastasis
Osteopontin - genetics
Osteopontin - metabolism
Phosphorylation
Physiology
Proteins
Review
Transcription factors
Tumors
Wound healing
Online AccessGet full text

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Abstract Complex interactions between tumor and host cells regulate systemic tumor dissemination, a process that begins early at the primary tumor site and goes on until tumor cells detach themselves from the tumor mass and start migrating into the blood or lymphatic vessels. Metastatic cells colonize the target organs and are capable of surviving and growing at distant sites. In this context, osteopontin (OPN) appears to be a key determinant of the crosstalk between cancer cells and the host microenvironment, which in turn modulates immune evasion. OPN is overexpressed in several human carcinomas and has been implicated in inflammation, tumor progression, and metastasis. Thus, it represents one of the most attracting targets for cancer therapy. Within the tumor mass, OPN is secreted in various forms either by the tumor itself or by stroma cells, and it can exert either pro- or antitumorigenic effects according to the cell type and tumor microenvironment. Thus, targeting OPN for therapeutic purposes needs to take into account the heterogeneous functions of the multiple OPN forms with regard to cancer formation and progression. In this review, we will describe the role of systemic, tumor-derived, and stroma-derived OPN, highlighting its pivotal role at the crossroads of inflammation and tumor progression.
AbstractList Complex interactions between tumor and host cells regulate systemic tumor dissemination, a process that begins early at the primary tumor site and goes on until tumor cells detach themselves from the tumor mass and start migrating into the blood or lymphatic vessels. Metastatic cells colonize the target organs and are capable of surviving and growing at distant sites. In this context, osteopontin (OPN) appears to be a key determinant of the crosstalk between cancer cells and the host microenvironment, which in turn modulates immune evasion. OPN is overexpressed in several human carcinomas and has been implicated in inflammation, tumor progression, and metastasis. Thus, it represents one of the most attracting targets for cancer therapy. Within the tumor mass, OPN is secreted in various forms either by the tumor itself or by stroma cells, and it can exert either pro- or antitumorigenic effects according to the cell type and tumor microenvironment. Thus, targeting OPN for therapeutic purposes needs to take into account the heterogeneous functions of the multiple OPN forms with regard to cancer formation and progression. In this review, we will describe the role of systemic, tumor-derived, and stroma-derived OPN, highlighting its pivotal role at the crossroads of inflammation and tumor progression.
Audience Academic
Author Clemente, Nausicaa
Quaglia, Marco
Cantaluppi, Vincenzo
Navalesi, Paolo
Salmi, Livia
Aspesi, Anna
Chiocchetti, Annalisa
Garzaro, Massimiliano
Raineri, Davide
Vaschetto, Rosanna
Dianzani, Umberto
Gentilli, Sergio
Castello, Luigi Mario
AuthorAffiliation 2 Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy
4 Department of Translational Medicine, Nephrology and Kidney Transplant Unit, University of Eastern Piedmont, Novara, Italy
1 Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
6 Department of Surgery, University of Eastern Piedmont, Novara, Italy
3 SCDU Anestesia e Rianimazione, Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara, Italy
7 Anestesia e Rianimazione, Università “Magna Graecia” di Catanzaro, Catanzaro, Italy
5 Department of Health Sciences, University of Eastern Piedmont, Novara, Italy
AuthorAffiliation_xml – name: 1 Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
– name: 5 Department of Health Sciences, University of Eastern Piedmont, Novara, Italy
– name: 7 Anestesia e Rianimazione, Università “Magna Graecia” di Catanzaro, Catanzaro, Italy
– name: 4 Department of Translational Medicine, Nephrology and Kidney Transplant Unit, University of Eastern Piedmont, Novara, Italy
– name: 3 SCDU Anestesia e Rianimazione, Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara, Italy
– name: 2 Department of Health Sciences and Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Eastern Piedmont, Novara, Italy
– name: 6 Department of Surgery, University of Eastern Piedmont, Novara, Italy
Author_xml – sequence: 1
  fullname: Cantaluppi, Vincenzo
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  fullname: Dianzani, Umberto
– sequence: 3
  fullname: Aspesi, Anna
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  fullname: Quaglia, Marco
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  fullname: Navalesi, Paolo
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28769537$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1159/000366331
10.1007/s00134-008-1268-4
10.1111/j.1582-4934.2010.01115.x
10.1159/000369685
10.1182/blood-2013-07-518167
10.1016/j.cellimm.2008.06.012
10.1016/j.critrevonc.2013.08.013
10.1016/j.cca.2014.02.024
10.1074/jbc.M109028200
10.1182/blood-2009-01-197988
10.1016/j.ccr.2012.02.022
10.1016/j.bcp.2010.06.029
10.1016/j.coph.2013.05.017
10.1146/annurev.immunol.021908.132532
10.1016/j.imbio.2013.06.003
10.3389/fimmu.2017.00321
10.1038/16717
10.1073/pnas.1423011112
10.1080/15216540500159424
10.1002/jcb.240560109
10.1186/1476-4598-9-101
10.3892/or.2014.3367
10.1016/j.matbio.2014.03.001
10.18632/oncotarget.8537
10.1007/s13277-014-2314-1
10.1038/nature14228
10.1158/0008-5472.CAN-09-1868
10.1016/S0304-3835(01)00607-3
10.1007/s00005-014-0294-x
10.1158/1078-0432.CCR-09-1631
10.1242/jcs.089466
10.1517/14728222.2014.925447
10.1016/j.surg.2011.05.015
10.2217/bmm-2016-0308
10.1016/j.humimm.2013.09.014
10.1155/2016/9345495
10.1016/j.canlet.2008.04.030
10.1016/S0092-8674(00)80108-7
10.1038/onc.2009.189
10.1159/000350133
10.1002/jcb.21558
10.1007/s12079-011-0130-6
10.1016/j.ccell.2015.02.015
10.1074/jbc.M507582200
10.1038/sj.onc.1208209
10.1634/stemcells.2008-0370
10.1007/s10555-010-9221-8
10.1074/jbc.M109.051490
10.1002/art.20808
10.1016/j.bbcan.2012.06.005
10.1038/nrc2618
10.1158/0008-5472.CAN-13-3334
10.1074/jbc.M110.189258
10.1016/S0014-5793(01)02690-4
10.1186/s13054-015-0782-3
10.1046/j.1440-1827.2002.01316.x
10.1016/j.tig.2008.10.012
10.1002/jcb.20379
10.1016/j.cell.2008.04.045
10.1182/blood-2003-05-1748
10.1126/science.287.5454.860
10.1186/bcr3600
10.1002/(SICI)1097-0215(19981023)79:5<502::AID-IJC10>3.0.CO;2-3
10.1038/nrc822
10.3390/cancers3043740
10.1177/039463201002300124
10.18632/oncotarget.10468
10.1016/j.matbio.2005.05.005
10.1016/j.canlet.2004.05.021
10.1074/jbc.M114.616888
10.1002/ijc.26359
10.1172/JCI18141
10.4049/jimmunol.0903245
10.1016/j.leukres.2007.03.034
10.1016/j.cell.2009.11.007
10.1016/j.cell.2010.01.025
10.1016/j.bbamcr.2015.09.018
10.1038/ni.3050
10.3892/mco.2014.480
10.1084/jem.194.9.1219
10.1093/neuonc/noq006
10.1074/jbc.M111.250035
10.1007/s00432-008-0415-1
10.1002/pros.10204
10.4049/jimmunol.171.2.1085
10.1128/MCB.22.12.4073-4085.2002
10.7150/jca.2.538
10.1007/BF00118184
10.3892/or.2013.2632
10.1007/s11060-016-2162-5
10.1111/j.1365-2567.2010.03335.x
10.1016/j.surg.2006.02.005
10.1038/sj.bjc.6605834
10.18632/oncotarget.13529
10.1038/onc.2013.549
10.1002/eji.201646391
10.1016/j.yexmp.2011.09.014
10.1016/j.prp.2010.11.004
10.1038/sj.onc.1210463
10.1074/jbc.M111.277996
10.1002/hep.26103
10.1097/BCR.0b013e318240541e
10.1073/pnas.0806089105
10.1158/0008-5472.CAN-08-2970
10.1016/j.febslet.2007.05.018
10.1111/j.0022-202X.2005.23680.x
10.1182/blood-2007-10-119099
10.1158/0008-5472.CAN-14-1990
10.1002/jcb.21159
10.1042/BJ20050341
10.1016/S1357-2725(02)00053-5
10.1007/s10585-004-2873-4
10.1016/j.cell.2010.03.014
10.1111/j.1582-4934.2008.00263.x
10.1093/carcin/bgi352
10.1002/1521-4141(2000012)30:12<3463::AID-IMMU3463>3.0.CO;2-5
10.1152/ajpcell.00477.2006
10.1016/j.oraloncology.2010.01.018
10.1038/sj.onc.1206209
10.1038/onc.2013.184
10.1016/j.autrev.2011.08.011
10.1038/nrd.2016.199
10.1158/0008-5472.CAN-07-2126
10.1158/0008-5472.CAN-06-3700
10.1038/aps.2012.47
10.1038/nm843
10.1164/ajrccm.160.4.9807094
10.1007/s12079-009-0068-0
10.1007/s00109-014-1183-9
10.1002/ijc.23204
10.1073/pnas.89.24.12160
10.1016/j.lfs.2016.04.003
10.1016/S0002-9440(10)64363-5
10.3892/or.2013.2666
10.1042/bj3040013
10.2174/156720507779939869
10.1007/s00432-010-0968-7
10.1017/S1462399408000641
10.1007/s13277-015-3495-y
10.1016/j.tcb.2005.12.005
10.1038/35078107
10.1016/j.bbcan.2017.02.005
10.1042/BJ20071021
10.1074/jbc.M207876200
10.1159/000444624
10.1038/35888
10.1016/j.it.2007.05.008
10.1016/j.ccr.2009.12.041
10.1155/2012/212893
10.1016/j.cardiores.2007.06.031
10.1038/mt.2008.235
10.1002/jcp.10394
10.1038/nri2356
10.1126/science.1175202
10.1016/j.biomaterials.2016.05.007
10.1073/pnas.0605752103
10.1016/j.devcel.2010.05.012
10.1155/2011/858425
10.1182/blood-2006-02-001412
10.1038/nrg2968
10.1016/0169-5002(95)00595-1
10.1158/0008-5472.CAN-14-0615
10.1074/jbc.M109.075010
10.4049/jimmunol.177.1.268
10.1038/bjc.2014.664
10.1002/mc.20452
10.1016/j.bbrc.2009.03.042
10.1038/nature00848
10.1016/j.cellimm.2004.01.001
10.1182/blood-2004-08-3228
10.1158/1541-7786.MCR-10-0463
10.1038/modpathol.3800768
10.1016/j.molmet.2014.03.004
10.1038/nm.2328
10.1172/JCI80007
10.1002/(SICI)1097-4652(199701)170:1<88::AID-JCP10>3.0.CO;2-K
10.1158/1078-0432.CCR-1405-2
10.1007/s10585-006-9007-0
10.1152/physiolgenomics.00138.2004
10.1007/s00795-009-0459-6
10.1080/10428194.2016.1243682
10.1002/(SICI)1097-4652(200007)184:1<118::AID-JCP13>3.0.CO;2-Y
10.1016/j.clindermatol.2009.06.012
10.1002/eji.1830261134
10.1016/j.humimm.2011.06.009
10.1111/j.1572-0241.2006.00679.x
10.1038/onc.2014.410
10.1073/pnas.211053698
10.2478/s11658-007-0031-0
10.4049/jimmunol.0802325
10.1002/ijc.10261
10.1046/j.0022-202x.2001.01467.x
10.1073/pnas.0802301105
10.1002/ijc.29454
10.3324/haematol.2010.023085
10.1158/0008-5472.CAN-05-3781
10.1182/blood-2012-12-475483
10.1111/j.1365-2567.2007.02682.x
10.1002/hep.24703
10.1016/S0024-3205(03)00196-6
10.1016/j.jneuroim.2005.02.020
10.1158/0008-5472.CAN-06-1002
10.1093/jnci/94.7.513
10.1038/ni1327
10.1007/s12026-010-8179-5
10.1016/j.cell.2011.02.013
10.4161/cc.5.15.3112
10.1128/CDLI.12.1.206-212.2005
10.1158/1078-0432.CCR-12-2788
10.1016/0006-291X(89)90837-1
10.1007/s00277-011-1161-z
10.1016/j.yjmcc.2009.06.015
10.1002/mc.20105
10.4143/crt.2009.41.1.29
10.1073/pnas.1113744109
10.1007/s10549-007-9865-4
10.1002/jcb.24462
10.1016/j.oraloncology.2008.12.006
ContentType Journal Article
Copyright Copyright © 2017 Luigi Mario Castello et al.
COPYRIGHT 2017 Hindawi Limited
Copyright © 2017 Luigi Mario Castello et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © 2017 Luigi Mario Castello et al. 2017
Copyright_xml – notice: Copyright © 2017 Luigi Mario Castello et al.
– notice: COPYRIGHT 2017 Hindawi Limited
– notice: Copyright © 2017 Luigi Mario Castello et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
– notice: Copyright © 2017 Luigi Mario Castello et al. 2017
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References 19887478 - Clin Cancer Res. 2009 Nov 15;15(22):6939-46
16785522 - J Immunol. 2006 Jul 1;177(1):268-79
16904962 - Surgery. 2006 Aug;140(2):132-40
20138012 - Cancer Cell. 2010 Feb 17;17(2):135-47
21763380 - Hum Immunol. 2011 Oct;72(10):930-4
15864800 - Mol Carcinog. 2005 Aug;43(4):225-36
17060621 - Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16472-7
18551128 - Nat Rev Immunol. 2008 Jul;8(7):533-44
28276434 - Sci Rep. 2017 Mar 09;7:43718
24120738 - Hum Immunol. 2014 Jan;75(1):76-80
19542428 - J Immunol. 2009 Jul 1;183(1):172-80
16474180 - Carcinogenesis. 2006 Jun;27(6):1134-45
18949382 - Int J Mol Med. 2008 Nov;22(5):619-32
28032860 - Cell Death Dis. 2016 Dec 29;7(12 ):e2564
19784742 - Med Mol Morphol. 2009 Sep;42(3):155-61
26325032 - J Clin Invest. 2015 Sep;125(9):3347-55
22728710 - Acta Pharmacol Sin. 2012 Aug;33(8):1004-12
25436971 - Nat Immunol. 2015 Jan;16(1):96-106
20219412 - Oral Oncol. 2010 Apr;46(4):302-6
20371344 - Cell. 2010 Apr 2;141(1):39-51
25620078 - Int J Cancer. 2015 Sep 1;137(5):1047-57
20360004 - J Biol Chem. 2010 Jun 4;285(23):18060-71
11520606 - Cancer Lett. 2001 Oct 10;171(2):215-22
24071501 - Crit Rev Oncol Hematol. 2014 Feb;89(2):330-41
22084644 - J Cancer. 2011;2:538-43
8080043 - Am J Pathol. 1994 Sep;145(3):610-23
23008732 - Clin Dev Immunol. 2012;2012:212893
18836077 - Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15884-9
25550515 - Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):494-9
24213109 - Cancers (Basel). 2011 Sep 28;3(4):3740-61
9823334 - Cancer Res. 1998 Nov 15;58(22):5206-15
22504460 - Autoimmun Rev. 2012 Dec;12(2):150-6
28326824 - Biomark Med. 2017 Apr;11(4):389-402
27807347 - Nat Rev Drug Discov. 2017 Mar;16(3):181-202
22302986 - J Cell Sci. 2012 Jan 15;125(Pt 2):376-86
25600648 - Cancer Res. 2015 Mar 15;75(6):963-73
17308118 - Cancer Res. 2007 Feb 15;67(4):1757-68
12531897 - J Biol Chem. 2003 May 23;278(21):18833-41
16691370 - Clin Exp Metastasis. 2005;22(8):663-73
11093165 - Eur J Immunol. 2000 Dec;30(12):3463-7
23867349 - Cell Physiol Biochem. 2013;32(1):171-9
21273622 - Anticancer Res. 2011 Jan;31(1):345-9
20386958 - Cancer Metastasis Rev. 2010 Jun;29(2):295-307
16012053 - IUBMB Life. 2005 Jun;57(6):441-7
19054589 - Trends Genet. 2009 Jan;25(1):30-8
12640447 - Nat Med. 2003 Apr;9(4):416-23
19285954 - Biochem Biophys Res Commun. 2009 May 8;382(3):514-8
18807011 - Intensive Care Med. 2008 Dec;34(12):2176-84
12075356 - Nature. 2002 Jun 20;417(6891):867-71
24944898 - Mol Metab. 2014 Mar 22;3(4):384-93
12189386 - Nat Rev Cancer. 2002 Jun;2(6):442-54
23728342 - Oncogene. 2014 May 1;33(18):2295-306
18522865 - Cancer Lett. 2008 Nov 8;270(2):181-90
23900428 - Oncol Rep. 2013 Oct;30(4):1860-8
27462610 - Biomed Res Int. 2016;2016:7310694
24899149 - Expert Opin Ther Targets. 2014 Aug;18(8):883-95
20627072 - Dev Cell. 2010 Jun 15;18(6):884-901
12377945 - J Leukoc Biol. 2002 Oct;72(4):752-61
24451146 - Breast Cancer Res. 2014 Jan 22;16(1):R8
18555776 - Cell. 2008 Jun 13;133(6):994-1005
27478856 - J Immunol Res. 2016;2016:9345495
11940202 - Pathol Int. 2002 Jan;52(1):19-24
11741994 - J Biol Chem. 2002 Mar 15;277(11):9175-82
22007306 - J Skin Cancer. 2011;2011:858425
17960616 - Int J Cancer. 2008 Feb 15;122(4):889-97
21151389 - Int J Clin Exp Pathol. 2010 Oct 08;3(8):763-7
21801960 - Surgery. 2011 Aug;150(2):224-30
27187277 - Biomaterials. 2016 Aug;98:131-42
25591760 - Cell Physiol Biochem. 2015;35(1):175-83
15051510 - Cell Immunol. 2004 Jan;227(1):1-11
14592838 - Blood. 2004 Feb 15;103(4):1376-82
8959677 - Lung Cancer. 1996 Nov;15(3):311-23
23589674 - Blood. 2013 Jun 13;121(24):4821-31
19417209 - Blood. 2009 Jul 2;114(1):49-59
27739925 - Leuk Lymphoma. 2017 Jun;58(6):1494-1497
22750751 - Biochim Biophys Acta. 2012 Dec;1826(2):400-6
1465456 - Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12160-4
18459127 - Mol Carcinog. 2009 Jan;48(1):14-23
8921969 - Eur J Immunol. 1996 Nov;26(11):2781-9
17226777 - J Cell Biochem. 2007 Jul 1;101(4):805-15
11920639 - Int J Cancer. 2002 Apr 10;98(5):707-12
21136203 - Immunol Res. 2011 Apr;49(1-3):160-72
12640658 - Prostate. 2003 Apr 1;55(1):30-8
9761120 - Int J Cancer. 1998 Oct 23;79(5):502-8
15679049 - Clin Exp Metastasis. 2004;21(6):515-23
7528752 - J Cell Biochem. 1994 Sep;56(1):48-51
21167650 - Pathol Res Pract. 2011 Feb 15;207(2):104-10
23934016 - Oncol Rep. 2013 Oct;30(4):1575-80
17952379 - Cell Mol Biol Lett. 2008;13(1):11-9
15855273 - Blood. 2005 Aug 1;106(3):946-55
18506372 - Int J Mol Med. 2008 Jun;21(6):777-84
21953299 - Hepatology. 2012 Feb;55(2):483-90
16880743 - Cell Cycle. 2006 Aug;5(15):1597-601
22561306 - J Burn Care Res. 2012 May-Jun;33(3):311-8
21965655 - J Biol Chem. 2011 Nov 18;286(46):40376-85
22340562 - Chin Med J (Engl). 2012 Jan;125(2):293-9
20378012 - Int J Immunopathol Pharmacol. 2010 Jan-Mar;23(1):263-9
21376230 - Cell. 2011 Mar 4;144(5):646-74
21826648 - Int J Cancer. 2012 Jul 15;131(2):322-33
23251004 - Clin Cancer Res. 2013 Feb 15;19(4):785-97
11786413 - Am J Pathol. 2002 Jan;160(1):195-204
25192720 - Tumour Biol. 2014 Dec;35(12):11799-808
19279573 - Nat Rev Cancer. 2009 Apr;9(4):239-52
9012788 - J Cell Physiol. 1997 Jan;170(1):88-100
20595097 - Haematologica. 2010 Nov;95(11):1897-904
17680800 - Immunology. 2007 Dec;122(4):466-75
20511184 - Neuro Oncol. 2010 Aug;12(8):765-75
18072945 - Biochem J. 2008 Apr 1;411(1):53-61
16848813 - Am J Gastroenterol. 2006 Sep;101(9):2051-9
24657887 - Matrix Biol. 2014 Jul;37:131-41
12697265 - Life Sci. 2003 May 9;72(25):2803-24
11469452 - J Rheumatol. 2001 Jul;28(7):1492-5
20823889 - Br J Cancer. 2010 Sep 7;103(6):861-9
17452979 - Oncogene. 2007 Sep 27;26(44):6361-71
27063991 - Life Sci. 2016 May 1;152:190-8
27409830 - Oncotarget. 2016 Aug 9;7(32):52003-52016
19213594 - Oral Oncol. 2009 Sep;45(9):798-802
14517343 - Mol Cancer Res. 2003 Sep;1(11):810-9
25798267 - Mol Clin Oncol. 2015 Mar;3(2):357-362
25545242 - PLoS One. 2014 Dec 29;9(12):e116210
23192608 - J Cell Biochem. 2013 May;114(5):1194-202
23891329 - Immunobiology. 2013 Nov;218(11):1402-10
18985031 - Mol Ther. 2009 Jan;17(1):153-61
11513858 - FEBS Lett. 2001 Aug 10;503(1):75-9
25731159 - Nature. 2015 Mar 5;519(7541):57-62
21383745 - Nat Med. 2011 Mar;17(3):320-9
20597997 - J Cell Mol Med. 2010 Aug;14(8):2037-44
20722758 - Immunology. 2011 Jan;132(1):39-48
11037970 - J Leukoc Biol. 2000 Oct;68(4):495-502
21516514 - J Cell Commun Signal. 2011 Jun;5(2):111-22
19885563 - Int J Oncol. 2009 Dec;35(6):1409-16
11676837 - J Invest Dermatol. 2001 Oct;117(4):949-57
26234583 - Sci Rep. 2015 Aug 03;5:12713
22439926 - Cancer Cell. 2012 Mar 20;21(3):309-22
15516973 - Oncogene. 2005 Jan 13;24(3):489-501
17964217 - Trends Immunol. 2007 Nov;28(11):491-6
16249175 - J Biol Chem. 2006 Jan 6;281(1):543-8
11929952 - J Natl Cancer Inst. 2002 Apr 3;94(7):513-21
24607327 - Clin Chim Acta. 2014 Jun 10;433:44-8
27888617 - Oncotarget. 2016 Dec 27;7(52):87219-87231
28254527 - Biochim Biophys Acta. 2017 Feb 28;1868(1):93-108
24363402 - Blood. 2014 Feb 20;123(8):1178-86
25858805 - Cancer Cell. 2015 Apr 13;27(4):462-72
16406521 - Trends Cell Biol. 2006 Feb;16(2):79-87
12606946 - Oncogene. 2003 Feb 27;22(8):1198-205
24917428 - Arch Immunol Ther Exp (Warsz). 2014 Dec;62(6):475-82
16849558 - Cancer Res. 2006 Jul 15;66(14):7119-27
19688069 - Cancer Res Treat. 2009 Mar;41(1):29-35
25035397 - Cancer Res. 2014 Sep 1;74(17):4706-19
7998923 - Biochem J. 1994 Nov 15;304 ( Pt 1):13-6
12024021 - Mol Cell Biol. 2002 Jun;22(12):4073-85
18535152 - Stem Cells. 2008 Aug;26(8):2114-23
8686754 - Am J Pathol. 1996 Jul;149(1):293-305
15696579 - J Cell Biochem. 2005 Apr 15;94(6):1218-33
15692970 - Arthritis Rheum. 2005 Feb;52(2):539-47
25099519 - J Mol Med (Berl). 2014 Dec;92(12):1271-81
25713073 - J Biol Chem. 2015 Apr 17;290(16):9959-73
19945376 - Cell. 2009 Nov 25;139(5):871-90
16740705 - Cancer Res. 2006 Jun 1;66(11):5676-85
19934330 - Cancer Res. 2009 Dec 15;69(24):9498-506
19798593 - J Cell Commun Signal. 2009 Dec;3(3-4):311-22
18353193 - Expert Rev Mol Med. 2008 Mar 19;10:e8
21263033 - Mol Cancer Res. 2011 Mar;9(3):280-93
11373684 - Nature. 2001 May 24;411(6836):494-8
9930702 - Nature. 1999 Jan 21;397(6716):263-6
23773801 - Curr Opin Pharmacol. 2013 Aug;13(4):595-601
15638386 - Rocz Akad Med Bialymst. 2004;49 Suppl 1:91-3
27489587 - Int J Hematol Oncol Stem Cell Res. 2016 Jul 1;10(3):120-9
2764941 - Biochem Biophys Res Commun. 1989 Aug 15;162(3):1453-9
17005603 - Am J Physiol Cell Physiol. 2007 Feb;292(2):C919-26
15885319 - J Neuroimmunol. 2005 Jun;163(1-2):172-8
10657301 - Science. 2000 Feb 4;287(5454):860-4
27294357 - J Neurooncol. 2016 Aug;129(1):165-71
7992848 - Am J Pathol. 1994 Dec;145(6):1450-62
18266970 - J Cell Mol Med. 2008 Dec;12(6A):2305-18
11593017 - Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12072-7
23079960 - Hepatology. 2013 Mar;57(3):1024-34
12847283 - J Immunol. 2003 Jul 15;171(2):1085-93
22179617 - J Biol Chem. 2012 Feb 3;287(6):3788-97
14737219 - PLoS Biol. 2004 Feb;2(2):E7
28097158 - J Immunol Res. 2016;2016:7675437
19573532 - J Mol Cell Cardiol. 2010 Mar;48(3):538-43
10473115 - Clin Cancer Res. 1999 Aug;5(8):2271-7
17316167 - Curr Alzheimer Res. 2007 Feb;4(1):67-72
21963599 - Exp Mol Pathol. 2012 Feb;92(1):13-9
17334344 - Mod Pathol. 2007 Apr;20(4):405-15
10508818 - Am J Respir Crit Care Med. 1999 Oct;160(4):1269-73
25531323 - Oncogene. 2015 Sep 10;34(37):4821-33
15869464 - Biochem J. 2005 Aug 15;390(Pt 1):285-92
20541679 - Clin Dermatol. 2010 May-Jun;28(3):275-80
8756718 - Cell. 1996 Aug 9;86(3):353-64
10825241 - J Cell Physiol. 2000 Jul;184(1):118-30
27160311 - Acta Haematol. 2016;136(1):52-61
12067984 - Cancer Res. 2002 Jun 15;62(12):3417-27
28386258 - Front Immunol. 2017 Mar 23;8:321
15596299 - Cancer Lett. 2005 Jan 10;217(1):87-95
19192668 - Anticancer Res. 2008 Nov-Dec;28(6B):4105-10
27050077 - Oncotarget. 2016 May 31;7(22):32156-71
21499294 - Nat Rev Genet. 2011 May;12(5):329-40
21321126 - J Biol Chem. 2011 Apr 1;286(13):11170-8
27601131 - Eur J Immunol. 2016 Nov;46(11):2669-2678
25398438 - Cancer Res. 2015 Jan 1;75(1):86-97
21258793 - Ann Hematol. 2011 May;90(5):493-508
18184868 - Blood. 2008 Mar 15;111(6):3200-10
20548025 - J Immunol. 2010 Jul 15;185(2):967-73
15479859 - Physiol Genomics. 2004 Dec 15;20(1):87-96
17910028 - J Cell Biochem. 2007 Nov 1;10
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97
99
(159) 1998; 58
(93) 2017; 7, article 43718
(245) 2001; 28
(13) 2000; 68
(202) 2006; 281
(180) 2015; 34
(102) 2016; 12
(145) 2012; 1826
(64) 2008; 28
(178) 2006; 5
(107) 2010; 28
(227) 2012; 125
(71) 2016; 7
(219) 2002; 62
(113) 2011; 31
200
201
(92) 2005; 24
203
204
205
206
207
(106) 2014; 35
208
209
210
211
212
213
214
217
(153) 2006; 2
(114) 2009; 9
220
100
221
222
223
103
(195) 2008; 21
224
104
225
226
(101) 2015; 5, article 12713
108
229
109
(216) 2010; 3
References_xml – volume: 3
  start-page: 763
  year: 2010
  ident: 216
  publication-title: International Journal of Clinical and Experimental Pathology
– ident: 51
  doi: 10.1159/000366331
– ident: 8
  doi: 10.1007/s00134-008-1268-4
– ident: 125
  doi: 10.1111/j.1582-4934.2010.01115.x
– ident: 50
  doi: 10.1159/000369685
– ident: 46
  doi: 10.1182/blood-2013-07-518167
– ident: 11
  doi: 10.1016/j.cellimm.2008.06.012
– ident: 36
  doi: 10.1016/j.critrevonc.2013.08.013
– volume: 149
  start-page: 293
  year: 1996
  ident: 176
  publication-title: The American Journal of Pathology
– ident: 103
  doi: 10.1016/j.cca.2014.02.024
– volume: 9, article e116210
  year: 2014
  ident: 86
  publication-title: PloS One
– ident: 132
  doi: 10.1074/jbc.M109028200
– ident: 89
  doi: 10.1182/blood-2009-01-197988
– ident: 121
  doi: 10.1016/j.ccr.2012.02.022
– volume: 28
  start-page: 4105
  year: 2008
  ident: 64
  publication-title: Anticancer Research
– ident: 243
  doi: 10.1016/j.bcp.2010.06.029
– ident: 189
  doi: 10.1016/j.coph.2013.05.017
– ident: 149
  doi: 10.1146/annurev.immunol.021908.132532
– ident: 2
  doi: 10.1016/j.imbio.2013.06.003
– ident: 244
  doi: 10.3389/fimmu.2017.00321
– ident: 82
  doi: 10.1038/16717
– volume: 7, article 43718
  year: 2017
  ident: 93
  publication-title: Scientific Reports
– ident: 26
  doi: 10.1073/pnas.1423011112
– ident: 16
  doi: 10.1080/15216540500159424
– ident: 158
  doi: 10.1002/jcb.240560109
– ident: 230
  doi: 10.1186/1476-4598-9-101
– ident: 246
  doi: 10.3892/or.2014.3367
– ident: 140
  doi: 10.1016/j.matbio.2014.03.001
– ident: 214
  doi: 10.18632/oncotarget.8537
– volume: 35
  start-page: 11799
  year: 2014
  ident: 106
  publication-title: Tumour Biology
  doi: 10.1007/s13277-014-2314-1
– ident: 1
  doi: 10.1038/nature14228
– ident: 152
  doi: 10.1158/0008-5472.CAN-09-1868
– ident: 97
  doi: 10.1016/S0304-3835(01)00607-3
– volume: 22
  start-page: 619
  year: 2008
  ident: 168
  publication-title: International Journal of Molecular Medicine
– ident: 58
  doi: 10.1007/s00005-014-0294-x
– ident: 111
  doi: 10.1158/1078-0432.CCR-09-1631
– ident: 191
  doi: 10.1242/jcs.089466
– ident: 28
  doi: 10.1517/14728222.2014.925447
– ident: 239
  doi: 10.1016/j.surg.2011.05.015
– ident: 211
  doi: 10.2217/bmm-2016-0308
– ident: 55
  doi: 10.1016/j.humimm.2013.09.014
– ident: 90
  doi: 10.1155/2016/9345495
– ident: 234
  doi: 10.1016/j.canlet.2008.04.030
– volume: 2016
  year: 2016
  ident: 9
  publication-title: Journal of Immunology Research
– ident: 169
  doi: 10.1016/S0092-8674(00)80108-7
– ident: 174
  doi: 10.1038/onc.2009.189
– ident: 52
  doi: 10.1159/000350133
– volume: 21
  start-page: 777
  year: 2008
  ident: 195
  publication-title: International Journal of Molecular Medicine
– ident: 128
  doi: 10.1002/jcb.21558
– volume: 72
  start-page: 752
  year: 2002
  ident: 15
  publication-title: Journal of Leukocyte Biology
– ident: 65
  doi: 10.1007/s12079-011-0130-6
– ident: 3
  doi: 10.1016/j.ccell.2015.02.015
– volume: 281
  start-page: 543
  year: 2006
  ident: 202
  publication-title: The Journal of Biological Chemistry
  doi: 10.1074/jbc.M507582200
– volume: 24
  start-page: 489
  year: 2005
  ident: 92
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1208209
– ident: 25
  doi: 10.1634/stemcells.2008-0370
– ident: 122
  doi: 10.1007/s10555-010-9221-8
– ident: 200
  doi: 10.1074/jbc.M109.051490
– ident: 40
  doi: 10.1002/art.20808
– volume: 1826
  start-page: 400
  year: 2012
  ident: 145
  publication-title: Biochimica et Biophysica Acta (BBA)-Reviews on Cancer
  doi: 10.1016/j.bbcan.2012.06.005
– volume: 58
  start-page: 5206
  year: 1998
  ident: 159
  publication-title: Cancer Research
– volume: 9
  start-page: 239
  year: 2009
  ident: 114
  publication-title: Nature Reviews. Cancer
  doi: 10.1038/nrc2618
– ident: 117
  doi: 10.1158/0008-5472.CAN-13-3334
– ident: 242
  doi: 10.1074/jbc.M110.189258
– ident: 85
  doi: 10.1016/S0014-5793(01)02690-4
– volume: 2, article e7
  year: 2004
  ident: 6
  publication-title: PLoS Biology
– ident: 23
  doi: 10.1186/s13054-015-0782-3
– ident: 33
  doi: 10.1046/j.1440-1827.2002.01316.x
– ident: 123
  doi: 10.1016/j.tig.2008.10.012
– ident: 129
  doi: 10.1002/jcb.20379
– ident: 146
  doi: 10.1016/j.cell.2008.04.045
– ident: 39
  doi: 10.1182/blood-2003-05-1748
– ident: 154
  doi: 10.1126/science.287.5454.860
– volume: 16
  start-page: R8
  year: 2014
  ident: 98
  publication-title: Breast Cancer Research
  doi: 10.1186/bcr3600
– ident: 135
  doi: 10.1002/(SICI)1097-0215(19981023)79:5<502::AID-IJC10>3.0.CO;2-3
– ident: 182
  doi: 10.1038/nrc822
– volume: 10
  start-page: 120
  year: 2016
  ident: 218
  publication-title: International Journal of Hematology-Oncology and Stem Cell Research
– ident: 151
  doi: 10.3390/cancers3043740
– ident: 43
  doi: 10.1177/039463201002300124
– volume: 7
  start-page: 52003
  year: 2016
  ident: 71
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.10468
– ident: 84
  doi: 10.1016/j.matbio.2005.05.005
– volume: 2
  start-page: 101
  year: 2006
  ident: 153
  publication-title: Journal of Cancer Molecules
– ident: 222
  doi: 10.1016/j.canlet.2004.05.021
– ident: 181
  doi: 10.1074/jbc.M114.616888
– ident: 205
  doi: 10.1002/ijc.26359
– ident: 115
  doi: 10.1172/JCI18141
– ident: 24
  doi: 10.4049/jimmunol.0903245
– ident: 204
  doi: 10.1016/j.leukres.2007.03.034
– ident: 185
  doi: 10.1016/j.cell.2009.11.007
– ident: 5
  doi: 10.1016/j.cell.2010.01.025
– volume: 1863
  start-page: 483
  year: 2016
  ident: 215
  publication-title: Biochimica et Biophysica Acta
  doi: 10.1016/j.bbamcr.2015.09.018
– ident: 83
  doi: 10.1038/ni.3050
– ident: 104
  doi: 10.3892/mco.2014.480
– ident: 17
  doi: 10.1084/jem.194.9.1219
– ident: 72
  doi: 10.1093/neuonc/noq006
– ident: 144
  doi: 10.1074/jbc.M111.250035
– ident: 220
  doi: 10.1007/s00432-008-0415-1
– ident: 194
  doi: 10.1002/pros.10204
– ident: 175
  doi: 10.4049/jimmunol.171.2.1085
– ident: 198
  doi: 10.1128/MCB.22.12.4073-4085.2002
– ident: 109
  doi: 10.7150/jca.2.538
– volume: 1
  start-page: 810
  year: 2003
  ident: 142
  publication-title: Molecular Cancer Research
– ident: 157
  doi: 10.1007/BF00118184
– ident: 54
  doi: 10.3892/or.2013.2632
– ident: 209
  doi: 10.1007/s11060-016-2162-5
– ident: 22
  doi: 10.1111/j.1365-2567.2010.03335.x
– volume: 12
  start-page: 277
  year: 2016
  ident: 102
  publication-title: Journal of Cancer Research and Therapeutics
– ident: 156
  doi: 10.1016/j.surg.2006.02.005
– ident: 126
  doi: 10.1038/sj.bjc.6605834
– volume: 68
  start-page: 495
  year: 2000
  ident: 13
  publication-title: Journal of Leukocyte Biology
– ident: 119
  doi: 10.18632/oncotarget.13529
– ident: 201
  doi: 10.1038/onc.2013.549
– ident: 207
  doi: 10.1002/eji.201646391
– ident: 66
  doi: 10.1016/j.yexmp.2011.09.014
– ident: 96
  doi: 10.1016/j.prp.2010.11.004
– ident: 91
  doi: 10.1038/sj.onc.1210463
– ident: 88
  doi: 10.1074/jbc.M111.277996
– ident: 53
  doi: 10.1002/hep.26103
– volume: 33
  start-page: 311
  year: 2012
  ident: 95
  publication-title: Journal of Burn Care & Research
  doi: 10.1097/BCR.0b013e318240541e
– volume: 105
  start-page: 15884
  year: 2008
  ident: 160
  publication-title: Proceedings of the National Academy of Sciences of the United States of America
  doi: 10.1073/pnas.0806089105
– ident: 197
  doi: 10.1158/0008-5472.CAN-08-2970
– ident: 241
  doi: 10.1016/j.febslet.2007.05.018
– ident: 30
  doi: 10.1111/j.0022-202X.2005.23680.x
– ident: 208
  doi: 10.1182/blood-2007-10-119099
– ident: 179
  doi: 10.1158/0008-5472.CAN-14-1990
– ident: 124
  doi: 10.1002/jcb.21159
– ident: 60
  doi: 10.1042/BJ20050341
– ident: 192
  doi: 10.1016/S1357-2725(02)00053-5
– volume: 145
  start-page: 610
  year: 1994
  ident: 133
  publication-title: The American Journal of Pathology
– ident: 29
  doi: 10.1007/s10585-004-2873-4
– ident: 150
  doi: 10.1016/j.cell.2010.03.014
– ident: 226
  doi: 10.1111/j.1582-4934.2008.00263.x
– ident: 229
  doi: 10.1093/carcin/bgi352
– ident: 81
  doi: 10.1002/1521-4141(2000012)30:12<3463::AID-IMMU3463>3.0.CO;2-5
– ident: 184
  doi: 10.1152/ajpcell.00477.2006
– ident: 49
  doi: 10.1016/j.oraloncology.2010.01.018
– ident: 141
  doi: 10.1038/sj.onc.1206209
– volume: 125
  start-page: 293
  year: 2012
  ident: 227
  publication-title: Chinese Medical Journal
– volume: 145
  start-page: 1450
  year: 1994
  ident: 34
  publication-title: The American Journal of Pathology
– volume: 33
  start-page: 2295
  year: 2014
  ident: 118
  publication-title: Oncogene
  doi: 10.1038/onc.2013.184
– ident: 47
  doi: 10.1016/j.autrev.2011.08.011
– ident: 237
  doi: 10.1038/nrd.2016.199
– ident: 170
  doi: 10.1158/0008-5472.CAN-07-2126
– ident: 167
  doi: 10.1158/0008-5472.CAN-06-3700
– ident: 116
  doi: 10.1038/aps.2012.47
– ident: 137
  doi: 10.1038/nm843
– ident: 172
  doi: 10.1164/ajrccm.160.4.9807094
– ident: 14
  doi: 10.1007/s12079-009-0068-0
– ident: 231
  doi: 10.1007/s00109-014-1183-9
– ident: 63
  doi: 10.1002/ijc.23204
– volume: 5
  start-page: 2271
  year: 1999
  ident: 32
  publication-title: Clinical Cancer Research
– volume: 89
  start-page: 12160
  year: 1992
  ident: 232
  publication-title: Proceedings of the National Academy of Sciences of the United States of America
  doi: 10.1073/pnas.89.24.12160
– ident: 212
  doi: 10.1016/j.lfs.2016.04.003
– ident: 177
  doi: 10.1016/S0002-9440(10)64363-5
– ident: 112
  doi: 10.3892/or.2013.2666
– ident: 61
  doi: 10.1042/bj3040013
– ident: 77
  doi: 10.2174/156720507779939869
– ident: 68
  doi: 10.1007/s00432-010-0968-7
– ident: 247
  doi: 10.1017/S1462399408000641
– volume: 36
  start-page: 7841
  year: 2015
  ident: 110
  publication-title: Tumour Biology
  doi: 10.1007/s13277-015-3495-y
– ident: 139
  doi: 10.1016/j.tcb.2005.12.005
– ident: 224
  doi: 10.1038/35078107
– ident: 38
  doi: 10.1016/j.bbcan.2017.02.005
– volume: 7, article e2564
  year: 2016
  ident: 147
  publication-title: Cell Death & Disease
– volume: 2016
  year: 2016
  ident: 105
  publication-title: BioMed Research International
– ident: 59
  doi: 10.1042/BJ20071021
– ident: 199
  doi: 10.1074/jbc.M207876200
– ident: 210
  doi: 10.1159/000444624
– volume: 11
  start-page: 135
  year: 2000
  ident: 171
  publication-title: Critical Reviews in Oncogenesis
– ident: 223
  doi: 10.1038/35888
– ident: 162
  doi: 10.1016/j.it.2007.05.008
– ident: 7
  doi: 10.1016/j.ccr.2009.12.041
– ident: 37
  doi: 10.1155/2012/212893
– ident: 166
  doi: 10.1016/j.cardiores.2007.06.031
– ident: 238
  doi: 10.1038/mt.2008.235
– ident: 76
  doi: 10.1002/jcp.10394
– ident: 148
  doi: 10.1038/nri2356
– ident: 164
  doi: 10.1126/science.1175202
– ident: 248
  doi: 10.1016/j.biomaterials.2016.05.007
– volume: 28
  start-page: 1492
  year: 2001
  ident: 245
  publication-title: The Journal of Rheumatology
– volume: 103
  start-page: 16472
  year: 2006
  ident: 196
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.0605752103
– ident: 187
  doi: 10.1016/j.devcel.2010.05.012
– ident: 108
  doi: 10.1155/2011/858425
– ident: 42
  doi: 10.1182/blood-2006-02-001412
– ident: 225
  doi: 10.1038/nrg2968
– ident: 31
  doi: 10.1016/0169-5002(95)00595-1
– ident: 79
  doi: 10.1158/0008-5472.CAN-14-0615
– ident: 87
  doi: 10.1074/jbc.M109.075010
– ident: 161
  doi: 10.4049/jimmunol.177.1.268
– ident: 62
  doi: 10.1038/bjc.2014.664
– ident: 56
  doi: 10.1002/mc.20452
– ident: 69
  doi: 10.1016/j.bbrc.2009.03.042
– ident: 203
  doi: 10.1038/nature00848
– ident: 206
  doi: 10.1016/j.cellimm.2004.01.001
– ident: 19
  doi: 10.1182/blood-2004-08-3228
– ident: 67
  doi: 10.1158/1541-7786.MCR-10-0463
– ident: 163
  doi: 10.1038/modpathol.3800768
– ident: 10
  doi: 10.1016/j.molmet.2014.03.004
– ident: 186
  doi: 10.1038/nm.2328
– volume: 31
  start-page: 345
  year: 2011
  ident: 113
  publication-title: Anticancer Research
– ident: 4
  doi: 10.1172/JCI80007
– ident: 183
  doi: 10.1002/(SICI)1097-4652(199701)170:1<88::AID-JCP10>3.0.CO;2-K
– ident: 134
  doi: 10.1158/1078-0432.CCR-1405-2
– ident: 143
  doi: 10.1007/s10585-006-9007-0
– ident: 57
  doi: 10.1152/physiolgenomics.00138.2004
– ident: 35
  doi: 10.1007/s00795-009-0459-6
– ident: 213
  doi: 10.1080/10428194.2016.1243682
– ident: 78
  doi: 10.1002/(SICI)1097-4652(200007)184:1<118::AID-JCP13>3.0.CO;2-Y
– volume: 28
  start-page: 275
  year: 2010
  ident: 107
  publication-title: Clinics in Dermatology
  doi: 10.1016/j.clindermatol.2009.06.012
– ident: 80
  doi: 10.1002/eji.1830261134
– ident: 45
  doi: 10.1016/j.humimm.2011.06.009
– ident: 131
  doi: 10.1111/j.1572-0241.2006.00679.x
– volume: 34
  start-page: 4821
  year: 2015
  ident: 180
  publication-title: Oncogene
  doi: 10.1038/onc.2014.410
– volume: 98
  start-page: 12072
  year: 2001
  ident: 193
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.211053698
– ident: 221
  doi: 10.2478/s11658-007-0031-0
– ident: 20
  doi: 10.4049/jimmunol.0802325
– ident: 173
  doi: 10.1002/ijc.10261
– volume: 62
  start-page: 3417
  year: 2002
  ident: 219
  publication-title: Cancer Research
– ident: 236
  doi: 10.1046/j.0022-202x.2001.01467.x
– volume: 105
  start-page: 7235
  year: 2008
  ident: 73
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.0802301105
– ident: 127
  doi: 10.1002/ijc.29454
– ident: 44
  doi: 10.3324/haematol.2010.023085
– ident: 155
  doi: 10.1158/0008-5472.CAN-05-3781
– ident: 217
  doi: 10.1182/blood-2012-12-475483
– ident: 21
  doi: 10.1111/j.1365-2567.2007.02682.x
– ident: 100
  doi: 10.1002/hep.24703
– ident: 48
  doi: 10.1016/S0024-3205(03)00196-6
– ident: 41
  doi: 10.1016/j.jneuroim.2005.02.020
– ident: 120
  doi: 10.1158/0008-5472.CAN-06-1002
– volume: 94
  start-page: 513
  year: 2002
  ident: 136
  publication-title: Journal of the National Cancer Institute
  doi: 10.1093/jnci/94.7.513
– ident: 75
  doi: 10.1038/ni1327
– ident: 74
  doi: 10.1007/s12026-010-8179-5
– ident: 188
  doi: 10.1016/j.cell.2011.02.013
– volume: 35
  start-page: 1409
  year: 2009
  ident: 70
  publication-title: International Journal of Oncology
– volume: 5, article 12713
  year: 2015
  ident: 101
  publication-title: Scientific Reports
– volume: 5
  start-page: 373
  year: 2011
  ident: 228
  publication-title: Molecular Medicine Reports
– volume: 5
  start-page: 1597
  year: 2006
  ident: 178
  publication-title: Cell Cycle
  doi: 10.4161/cc.5.15.3112
– ident: 18
  doi: 10.1128/CDLI.12.1.206-212.2005
– ident: 190
  doi: 10.1158/1078-0432.CCR-12-2788
– ident: 130
  doi: 10.1016/0006-291X(89)90837-1
– ident: 233
  doi: 10.1007/s00277-011-1161-z
– ident: 94
  doi: 10.1016/j.yjmcc.2009.06.015
– ident: 27
  doi: 10.1002/mc.20105
– ident: 99
  doi: 10.4143/crt.2009.41.1.29
– volume: 109
  start-page: 2491
  year: 2012
  ident: 165
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.1113744109
– ident: 240
  doi: 10.1007/s10549-007-9865-4
– volume: 114
  start-page: 1194
  year: 2013
  ident: 12
  publication-title: Journal of Cellular Biochemistry
  doi: 10.1002/jcb.24462
– ident: 138
  doi: 10.1016/j.oraloncology.2008.12.006
– volume: 49
  start-page: 91
  year: 2004
  ident: 235
  publication-title: Roczniki Akademii Medycznej w Białymstoku
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Snippet Complex interactions between tumor and host cells regulate systemic tumor dissemination, a process that begins early at the primary tumor site and goes on...
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SubjectTerms Angiogenesis
Animals
Apoptosis
Cancer therapies
Cell adhesion & migration
Colleges & universities
Cytokines
Development and progression
Disease Progression
Extracellular matrix
Fibroblasts
Health aspects
Health sciences
Humans
Inflammation
Inflammation - genetics
Inflammation - metabolism
Kinases
Neoplasm Metastasis
Osteopontin - genetics
Osteopontin - metabolism
Phosphorylation
Physiology
Proteins
Review
Transcription factors
Tumors
Wound healing
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Title Osteopontin at the Crossroads of Inflammation and Tumor Progression
URI https://search.emarefa.net/detail/BIM-1188315
https://dx.doi.org/10.1155/2017/4049098
https://www.ncbi.nlm.nih.gov/pubmed/28769537
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Volume 2017
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