Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes - Kraakman, Michael J.; Lee, Man K.S.; Al-Sharea, Annas; Dragoljevic, Dragana; Barrett, Tessa J.; Montenont, Emilie; Basu, Debapriya; Heywood, Sarah; Kammoun, Helene L.; Flynn, Michelle; Whillas, Alexandra; Hanssen, Nordin M.J.; et al. (The Journal of clinical investigation, 2017)
Keywords: Advanced glycosylation end products; Animals; Antiplatelet therapy; Atherogenesis; Atherosclerosis; Atherosclerosis - immunology; Atherosclerosis - metabolism; Biomedical research; Blood platelets; Blood Platelets - physiology; Bone marrow; Calcium; Calcium binding proteins; Calgranulin A - physiology; Calgranulin B - physiology; Cardiovascular disease; Cardiovascular diseases; Cell proliferation; Chemokines; Complications and side effects; Cytokines; Development and progression; Diabetes; Diabetes mellitus; Diabetes Mellitus, Experimental - complications; Diabetes Mellitus, Experimental - immunology; Diabetes Mellitus, Experimental - metabolism; Glucose; Glycosylation; Health aspects; Hemoglobin; Hepatocytes; Humans; Hyperglycemia; Inflammation; Interleukin 6; Ischemia; Kupffer cells; Leukocytes (neutrophilic); Lupus; Male; Megakaryocytes; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mortality; Myocardial ischemia; Na+/glucose cotransporter; Neutrophils; Neutrophils - metabolism; Osteoprogenitor cells; Platelets; Proteins; Rodents; Sodium; Stem cells; Thrombocytosis; Thrombocytosis - immunology; Thrombocytosis - metabolism; Thrombosis