Oral frailty and neurodegeneration in Alzheimer's disease

• Published in: Neural regeneration research Vol. 16; no. 11; pp. 2149 - 2153
• Main Authors: Dibello, Vittorio, Lozupone, Madia, Manfredini, Daniele, Dibello, Antonio, Zupo, Roberta, Sardone, Rodolfo, Daniele, Antonio, Lobbezoo, Frank, Panza, Francesco
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.11.2021; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Institute of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands%Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy%School of Dentistry, Department of Biomedical Technologies, University of Siena, Siena, Italy%Azienda Sanitaria Locale (ASL) Bari, Bari, Italy%Frailty Phenotypes Research Unit, "Salus in Apulia Study", National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, Bari, Italy%Institute of Neurology, Catholic University of Sacred Heart, Rome, Italy; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Alzheimer's disease; biomarkers; cognitive frailty; dementia; diet; mild cognitive impairment; nutritional frailty; oral health; oral microbiota; periodontal disease; tooth loss; Complications and side effects; Frail elderly; Frailty; Health aspects; Microbiota; Neurodegeneration; Oral health; Review; Italy; oral microbiota; biomarkers; dementia; oral health; mild cognitive impairment; diet; nutritional frailty; cognitive frailty; tooth loss; periodontal disease

Frailty is a critical intermediate status of the aging process with a multidimensional and multisystem nature and at higher risk for adverse health-related outcomes, including falls, disability, hospitalizations, institutionalization, mortality, dementia, and Alzheimer's disease. Among differen...