Obesity as a clinical predictor for severe manifestation of dengue: a systematic review and meta-analysis

• Published in: BMC infectious diseases Vol. 23; no. 1; pp. 502 - 13
• Main Authors: Chen, Chao-Ying, Chiu, Yu-Yao, Chen, Yu-Cheng, Huang, Chung-Hao, Wang, Wen-Hung, Chen, Yen-Hsu, Lin, Chun-Yu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 31.07.2023; BioMed Central; BMC
• Subjects: Adult; Asymptomatic; Bias; Body mass index; Body weight; Case studies; Case-Control Studies; Child; Children; Coronaviruses; COVID-19; Cross-Sectional Studies; Dengue; Dengue fever; Dengue hemorrhagic fever; Development and progression; Diseases; Health aspects; Humans; Immune response; Infections; Infectious diseases; Influence; Medical research; Medicine, Experimental; Meta-analysis; Methods; Mortality; Nutritional status; Obesity; Obesity - complications; Odds Ratio; Overweight; Patients; Pediatrics; Prognosis; Severe Dengue - complications; Severe Dengue - diagnosis; Statistical analysis; Systematic review; Vector-borne diseases; Viral infections; Viruses; Taiwan; Obesity; Dengue; Prognosis

Severe dengue often leads to poor clinical outcomes and high mortality; as a result, it is of vital importance to find prognostic factors associated with the severe form of dengue. Obesity is known to deteriorate many infectious diseases due to impaired immune responses. Several studies have suggest...