Epidemiological Realities of Alcoholic Liver Disease: Global Burden, Research Trends, and Therapeutic Promise

• Published in: Gene Expression Vol. 20; no. 2; pp. 105 - 118
• Main Authors: Xiao, Jia, Wang, Fei, Wong, Nai-Kei, Lv, Yi, Liu, Yingxia, Zhong, Jiajun, Chen, Shuaiyin, Li, Wei, Koike, Kazuo, Liu, Xiaowei, Wang, Hua
• Format: Journal Article
• Language: English
• Published: Elmsford, NY Cognizant Communication Corporation 11.11.2020; Xia & He Publishing
• Subjects: Active control; Affluence; Alcohol Abuse; Alcohol use; Alcoholic Liver Disease (ald); Alcoholism; Alcohols; Clinical trials; Correlation analysis; Developing countries; Disease Mechanisms; Empirical analysis; Epidemiology; Fatty liver; Females; Global Burden of Disease; Global Disease Burden; Global health; GNI; Gross National Income; Growth factors; Hepatitis; Humans; Income distribution; Inflammation; Intervention; LDCs; Liver; Liver cancer; Liver cirrhosis; Liver diseases; Liver Diseases, Alcoholic; Marketing; Molecular modelling; Monoclonal antibodies; Pathophysiology; Per capita; Probiotics; Public health; Public Health Policy; Review; Socioeconomic Factors; Trends; Tumor necrosis factor-TNF; Brunei; South Korea; United States > US; Qatar; China; Nigeria; Russia; Indonesia; India

Globally, alcohol consumption contributes to more than 3 million deaths each year. While much of its ramifications is preventable, a coherent public health discourse on how to limit alcohol-related harm has been overdue. By synthesizing information from national and global databases, we show in this...