The human visual cortex responds to gene therapy–mediated recovery of retinal function - Ashtari, Manzar; Cyckowski, Laura L.; Monroe, Justin F.; Marshall, Kathleen A.; Chung, Daniel C.; Auricchio, Alberto; Simonelli, Francesca; Leroy, Bart P.; Maguire, Albert M.; Shindler, Kenneth S.; Bennett, Jean (The Journal of clinical investigation, 2011)
Keywords: Adult; Biomedical research; Carrier Proteins - genetics; Carrier Proteins - physiology; Child; cis-trans-Isomerases; Dependovirus - genetics; DNA, Complementary - administration & dosage; DNA, Complementary - genetics; DNA, Complementary - therapeutic use; Eye Proteins - genetics; Eye Proteins - physiology; Gene therapy; Genes; Genetic Therapy; Genetic Vectors - therapeutic use; Humans; Leber Congenital Amaurosis - genetics; Leber Congenital Amaurosis - physiopathology; Leber Congenital Amaurosis - therapy; Magnetic Resonance Imaging; Photic Stimulation; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - physiology; Recovery of Function; Reflex, Pupillary - radiation effects; Sensory Deprivation; Sensory Thresholds; Technical Advance; Visual Cortex - physiopathology; Pennsylvania